The Need for Visits to Social and Vocational Programs for the Mentally Ill as Part of General Psychiatry Residency Training

Background. Comprehensive treatment planning for psychiatric illnesses should be based on a biopsychosocial model of treatment to address the acuity and chronicity of these disorders. To achieve this goal, knowledge about pharmacological, psychological, and social aspects of the treatment plan should be presented as an integral part of general psychiatry residency training. This survey study was conducted to examine how many programs provide training where residents have scheduled visits to social and vocational mental health service organizations in the community and to identify potential obstacles to including this rotation in general psychiatry residency training. Methods. A voluntary, anonymous survey was sent via SurveyMonkey® to the program directors of all general psychiatry residency programs in the United States. The survey consisted of five questions designed to assess if their programs had a rotation where residents visit social and vocational programs in the community designed for mentally ill patients to provide knowledge of the community mental health resources to their residents. Results. Of the 168 survey invitations issued, 73 (44%) responded. Fifty-six responders acknowledged that their residents were required to visit a community mental health organization, but their programs did not offer visits to community social and vocational programs. Seventeen program directors reported that their program did not provide this experience to their residents and indicated a desire to include such a rotation. Conclusions. Community mental health service organization visits should enhance knowledge of psychiatry residents about community mental health resources and indirectly promote better patient care. Information obtained from this survey should create discussion to work toward better psychiatric resident training

Vocal behaviour and feeding ecology of killer whales Orcinus orca around Shetland, UK

Killer whales Orcinus orca are sighted regularly off Shetland, UK, but little is known about their numbers, diet and population identity. We aimed to relate vocal behaviour to diet of killer whales around Shetland in order to investigate population structure and differences in feeding strategies. Fieldwork was conducted in the summers of 2008 and 2009. We located killer whales through a sightings network and shore-based scans and collected photo-ID data, behavioural information, feeding data and acoustic recordings from a small boat. The majority of encounters (n = 14) were of small groups (1 to 15 individuals) travelling close to shore and feeding on marine mammals. Two encounters were with large groups (20+ individuals) feeding on herring Clupea harengus farther offshore. Seal-hunting groups vocalised rarely, producing pulsed calls, echolocation clicks and whistles almost exclusively when surface-active or milling after a kill. Herring-eating groups were largely silent during one encounter, but very vocal during the other. Analysis of pulsed calls identified 6 stereotyped call types for seal-hunting groups and 7 for herring-eating groups. No call types were shared between both kinds of groups. The vocal behaviour of seal-hunting groups showed striking parallels to that of Pacific marine mammal specialists and presumably evolved to decrease detection by acoustically sensitive prey. One call type produced by Shetland herring-eating killer whales matched a vocalisation that a previous study had described from Iceland and identified as a possible herding call that may function to concentrate herring during feeding. These findings point to behavioural and dietary specialisation among Shetland killer whales, which should be taken into account when making management decisions affecting these animals

Ancient and modern stickleback genomes reveal the demographic constraints on adaptation

Adaptation is typically studied by comparing modern populations with contrasting environments. Individuals persisting in the ancestral habitat are typically used to represent the ancestral founding population; however, it has been questioned whether these individuals are good proxies for the actual ancestors.1 To address this, we applied a paleogenomics approach2 to directly access the ancestral genepool: partially sequencing the genomes of two 11- to 13,000-year-old stickleback recovered from the transitionary layer between marine and freshwater sediments of two Norwegian isolation lakes3 and comparing them with 30 modern stickleback genomes from the same lakes and adjacent marine fjord, in addition to a global dataset of 20 genomes.4 The ancient stickleback shared genome-wide ancestry with the modern fjord population, whereas modern lake populations have lost substantial ancestral variation following founder effects, and subsequent drift and selection. Freshwater-adaptive alleles found in one ancient stickleback genome have not risen to high frequency in the present-day population from the same lake. Comparison to the global dataset suggested incomplete adaptation to freshwater in our modern lake populations. Our findings reveal the impact of population bottlenecks in constraining adaptation due to reduced efficacy of selection on standing variation present in founder populations.acceptedVersion"© 2021. This is the authors’ accepted and refereed manuscript to the article. Locked until 10.3.2022 due to copyright restrictions. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Complete Mitochondrial Genomes Provide Evidence of a Killer Whale Refugium Off the Coast of Japan During the Last Glacial Maximum

Aim: During glacial periods, highly mobile species often shifted to warmer, ice-free regions known as refugia, which frequently maintained higher genetic diversity than newly colonised areas after glacial retreat. We analyse complete mitogenome sequences from 11 killer whale samples in Nemuro Strait to test the hypothesis that waters around Japan may have preserved a refugial population of killer whales that retained historical genetic diversity. Location: Western North Pacific. Taxon: Orcinus orca ater, Cetacea. Methods: Sequencing of complete mitochondrial genomes (16,387 bp) from 11 killer whale samples collected in the Nemuro Strait, southern Okhotsk Sea. Distribution of haplotypes in the social network was visualised using the data on social associations. The probability of individuals belonging to one or more possible reproductive groups was estimated based on 17 microsatellite loci. Results: Seven samples shared a haplotype common in the western North Pacific, one had a haplotype previously found only in the eastern North Pacific, and three exhibited novel haplotypes. Killer whales with different haplotypes were connected into a single social network, but some degree of social segregation is evident within the network. No significant genetic clustering based on microsatellite markers was detected between Nemuro Strait and areas near the Kamchatka Peninsula. Main Conclusions: With five distinct mitogenomes, Nemuro Strait now ranks second in mitogenomic diversity after the central Aleutian Islands. These findings support the hypothesis of a glacial refugium off Japan preserving a portion of pre-glacial genetic diversity. The lack of genetic clustering between Nemuro Strait and areas near the Kamchatka Peninsula indicates that all R-type killer whales in the western North Pacific belong to a single population. The low mitogenomic diversity north of Nemuro Strait likely reflects a founder effect, where a few groups colonised the region after the LGM, while most of the population with higher genetic diversity remained near Japan.</p

Fast and Accurate Retrieval of Methane Concentration From Imaging Spectrometer Data Using Sparsity Prior

The strong radiative forcing by atmospheric methane has stimulated interest in identifying natural and anthropogenic sources of this potent greenhouse gas. Point sources are important targets for quantification, and anthropogenic targets have the potential for emissions reduction. Methane point-source plume detection and concentration retrieval have been previously demonstrated using data from the Airborne Visible InfraRed Imaging Spectrometer-Next Generation (AVIRIS-NG). Current quantitative methods have tradeoffs between computational requirements and retrieval accuracy, creating obstacles for processing real-time data or large data sets from flight campaigns. We present a new computationally efficient algorithm that applies sparsity and an albedo correction to matched the filter retrieval of trace gas concentration path length. The new algorithm was tested using the AVIRIS-NG data acquired over several point-source plumes in Ahmedabad, India. The algorithm was validated using the simulated AVIRIS-NG data, including synthetic plumes of known methane concentration. Sparsity and albedo correction together reduced the root-mean-squared error of retrieved methane concentration-path length enhancement by 60.7% compared with a previous robust matched filter method. Background noise was reduced by a factor of 2.64. The new algorithm was able to process the entire 300 flight line 2016 AVIRIS-NG India campaign in just over 8 h on a desktop computer with GPU acceleration