61 research outputs found

    Seismological evidence for crustal-scale thrusting in the Zagros mountain belt (Iran)

    Get PDF
    International audienceCrustal receiver functions computed from the records of 45 temporary seismological stations installed on a 620-km long profile across central Zagros provide the first direct evidence for crustal thickening in this mountain belt. Due to a rather short 14-km average station spacing, the migrated section computed from radial receiver functions displays the Moho depth variations across the belt with good spatial resolution. From the coast of the Persian Gulf to 25 km southwest of the Main Zagros Thrust (MZT), the Moho is almost horizontal with slight depth variations around 45 km. Crustal thickness then increases abruptly to a maximum of ~70 km beneath the Sanandaj-Sirjan metamorphic zone, between 50 and 90 km northeast of the surface exposure of the MZT. Further northeast, the Moho depth decreases to ~42 km beneath the Urumieh-Dokhtar magmatic assemblage and the southern part of the Central Iranian micro-continent. The region of thickest crust is located ~75 km to the northeast of the Bouguer anomaly low at –220 mgals. Gravity modelling shows that the measured Moho depth variations can be reconciled with gravity observations by assuming that the crust of Zagros underthrusts the crust of central Iran along the MZT considered as a crustal-scale structure. This hypothesis is compatible with shortening estimates by balanced cross-sections of the Zagros folded belt, as well as with structural and petrological studies of the metamorphic Sanandaj-Sirjan zone

    Analogue model of rift linkage and inversion with application to the Western Alps

    Get PDF
    Along-strike segmentation of orogens raises questions because its causes may predate orogeny in relation to structural inheritance. Here we focus on rift/margin linkage domains and their inversion by using analogue models with image analysis to extract the 3D strain field. Extensional models document, depending on the strike-perpendicular offset and the brittle-crust thickness, three types of rift linkage modes: (1) oblique linkage with early T-fault, (2) strongly-oblique linkage with R-fault network and, (3) transfer-linkage with late Y-strike-slip fault. Analogue model of inverted rift basins is used to analyse the misunderstood tectonic evolution of transition zones in the segmented Western Alpine belt

    Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>G protein-coupled receptors (GPCRs) are major players in cell communication, regulate a whole range of physiological functions during development and throughout adult life, are affected in numerous pathological situations, and constitute so far the largest class of drugable targets for human diseases. The corresponding genes are usually expressed at low levels, making accurate, genome-wide quantification of their expression levels a challenging task using microarrays.</p> <p>Results</p> <p>We first draw an inventory of all endo-GPCRs encoded in the murine genome. To profile GPCRs genome-wide accurately, sensitively, comprehensively, and cost-effectively, we designed and validated a collection of primers that we used in quantitative RT-PCR experiments. We experimentally validated a statistical approach to analyze genome-wide, real-time PCR data. To illustrate the usefulness of this approach, we determined the repertoire of GPCRs expressed in cerebellar granule neurons and neuroblasts during postnatal development.</p> <p>Conclusions</p> <p>We identified tens of GPCRs that were not detected previously in this cell type; these GPCRs represent novel candidate players in the development and survival of cerebellar granule neurons. The sequences of primers used in this study are freely available to those interested in quantifying GPCR expression comprehensively.</p

    Cocasseries

    No full text

    De Drake à Chatwin : rhétoriques de la découverte

    No full text
    ISBN : 278-2-84788-107-3Présentation des explorateurs étudiés : p. 217 à 222Book, Edited"Vers la fin du xvie siècle, lorsque la reine Élisabeth perçoit que la puissance de l'Angleterre devra nécessairement s'appuyer sur la maîtrise des mers, les Anglais prennent le large pour de nouveaux horizons. L'objectif principal de cet ouvrage collectif est d'étudier les modalités des premières rencontres dans les «?zones de contact?», lieux incertains où le même et l'autre sont jetés ensemble sur une scène à partager. Se dessine un espace intersubjectif non entièrement déterminé, où se mettent en place, s'inventent, s'ajustent, se négocient les modalités, linguistiques et pragmatiques, cognitives et herméneutiques, d'une expérience de l'Autre. On a voulu analyser en même temps dans quelle mesure l'identité anglaise, individuelle et collective, s'était nourrie de ces mises en contexte, tout en se construisant dans des récits particuliers. De la violence impérialiste au descriptif ethnographique, de la nostalgie de la transparence originelle à la revendication joyeuse de l'hybridation ou à la méditation métatextuelle, de Drake à Chatwin, combien d'utopies et de mirages, combien de scénarios fantasmatiques, combien de mises en scène de soi, pour satisfaire toujours à nouveau le désir de voir l'invu et de dire l'inouï ?

    Analogue model of rift linkage and inversion with application to the Western Alps

    Get PDF
    International audienceAlong-strike segmentation of orogens raises questions because its causes may predate orogeny in relation to structural inheritance. Here we focus on rift/margin linkage domains and their inversion by using analogue models with image analysis to extract the 3D strain field. Extensional models document, depending on the strike-perpendicular offset and the brittle-crust thickness, three types of rift linkage modes: (1) oblique linkage with early T-fault, (2) strongly-oblique linkage with R-fault network and, (3) transfer-linkage with late Y-strike-slip fault. Analogue model of inverted rift basins is used to analyse the misunderstood tectonic evolution of transition zones in the segmented Western Alpine belt
    corecore