Microlens Parallax Asymmetries Toward the LMC

If the microlensing events now being detected toward the Large Magellanic Cloud (LMC) are due to lenses in the Milky Way halo, then the events should typically have asymmetries of order 1% due to parallax from the reflex motion of the Earth. By contrast, if the lenses are in the LMC, the parallax effects should be negligible. A ground-based search for such parallax asymmetries would therefore clarify the location of the lenses. A modest effort (2 hours per night on a 1 m telescope) could measure 15 parallax asymmetries over 5 years and so marginally discriminate between the halo and the LMC as the source of the lenses. A dedicated 1 m telescope would approximately double the number of measurements and would therefore clearly distinguish between the alternatives. However, compared to satellite parallaxes, the information extracted from ground-based parallaxes is substantially less useful for understanding the nature of the halo lenses (if that is what they are). The backgrounds of asymmetries due to binary-source and binary-lens events are estimated to be approximately 7% and 12% respectively. These complicate the interpretation of detected parallax asymmetries, but not critically.Comment: Submitted to ApJ, 17 pages, including 2 embedded figure

MACHOs, White Dwarfs, and the Age of the Universe

(Abridged Abstract) A favored interpretation of recent microlensing measurements towards the Large Magellanic Cloud implies that a large fraction (i.e. 10--50%) of the mass of the galactic halo is composed of white dwarfs. We compare model white dwarf luminosity functions to the data from the observational surveys in order to determine a lower bound on the age of any substantial white dwarf halo population (and hence possibly on the age of the Universe). We compare various theoretical white dwarf luminosity functions, in which we vary hese three parameters, with the abovementioned survey results. From this comparison, we conclude that if white dwarfs do indeed constitute more than 10% of the local halo mass density, then the Universe must be at least 10 Gyr old for our most extreme allowed values of the parameters. When we use cooling curves that account for chemical fractionation and more likely values of the IMF and the bolometric correction, we find tighter limits: a white dwarf MACHO fraction of 10% (30%) requires a minimum age of 14 Gyr (15.5 Gyr). Our analysis also indicates that the halo white dwarfs almost certainly have helium-dominated atmospheres.Comment: Final version accepted for publication, straight TeX formate, 6 figs, 22 page

EEG Classification based on Image Configuration in Social Anxiety Disorder

The problem of detecting the presence of Social Anxiety Disorder (SAD) using Electroencephalography (EEG) for classification has seen limited study and is addressed with a new approach that seeks to exploit the knowledge of EEG sensor spatial configuration. Two classification models, one which ignores the configuration (model 1) and one that exploits it with different interpolation methods (model 2), are studied. Performance of these two models is examined for analyzing 34 EEG data channels each consisting of five frequency bands and further decomposed with a filter bank. The data are collected from 64 subjects consisting of healthy controls and patients with SAD. Validity of our hypothesis that model 2 will significantly outperform model 1 is borne out in the results, with accuracy $6$--$7\%$ higher for model 2 for each machine learning algorithm we investigated. Convolutional Neural Networks (CNN) were found to provide much better performance than SVM and kNNs

Microlens Parallaxes with SIRTF

The Space Infrared Telescope Facility (SIRTF) will drift away from the Earth at about 0.1 AU/yr. Microlensing events will therefore have different characteristics as seen from the satellite and the Earth. From the difference, it is possible in principle to measure v-tilde, the transverse velocity of the lens projected onto the observer plane. Since v-tilde has very different values for different populations (disk, halo, Large Magellanic Cloud), such measurements could help identify the location, and hence the nature, of the lenses. I show that the method previously developed by Gould for measuring such satellite parallaxes fails completely in the case of SIRTF: it is overwhelmed by degeneracies which arise from fact that the Earth and satellite observations are in different band passes. I develop a new method which allows for observations in different band passes and yet removes all degeneracies. The method combines a purely ground-based measurement of the "parallax asymmetry" with a measurement of the delay between the time the event peaks at the Earth and satellite. In effect, the parallax asymmetry determines the component of v-tilde in the Earth-Sun direction, while the delay time measures the component of v-tilde in the direction of the Earth's orbit.Comment: 21 pages plus 3 figure

Is alcohol consumption associated with poor academic achievement in university students?

BACKGROUND: We assessed associations between educational achievement and alcohol consumption. METHODS: We employed five alcohol consumption measures (length of time of and amount consumed during most recent drinking occasion, frequency of alcohol consumption, heavy episodic drinking, problem drinking); and three educational achievement indicators (students' subjective importance of achieving good grades, students' appraisal of their academic performance in comparison with peers, students' actual module mark). RESULTS: Males were positively associated with all five alcohol consumption measures. Age was negatively associated with three alcohol consumption measures. While students importance of good grades was negatively associated with three alcohol consumption measures, academic performance in comparison with peers was negatively associated with heavy episodic drinking. Actual module mark was not associated with any alcohol consumption measure. CONCLUSIONS: Alcohol consumption showed negative associations with motivation for and subjectively achieved academic performance. University alcohol prevention activities might have positive impact on students' academic success

Climate change and biodiversity; impacts, vulnerability and mitigation in Indian perspective : A review

As per the nature of law, changes are bound to be happening in the system if any component of the system gets altered by any means. Change of climate and subsequently loss of biodiversity threatens the existence of human being. The loss of biodiversity, which has been happening worldwide, poses a serious threat to the anthro-pological system. An investigation of the current trend and future scenario shows that this loss is likely to continue in the foreseeable times. India has a huge variety of biodiversity and in the last few decades, its biodiversity has come under threat from climate change which accelerated by the anthropogenic activities of various sources of pollution. The review shows that climate change is a serious environmental challenge that undermines the determination for sustainable development. Climate change has become the most crucial environmental concern of the decade. Much attention is rightly focused on reducing carbon emissions and greenhouse gases from industrial, energy and transport sector through reduction in fuel consumption and use of renewable/green energy. However, as countries are looking for mitigation and adaptation processes, protection of natural habitats is a key factor of climate change strategies. Strengthened support for protected areas and more sustainable resource management can contribute to strategies as well as for protection of the biological resources and ecosystem. Climate change is developing as one of the greatest threats to biodiversity, increasing pressures on genetic resources, species and populations. Biodiver-sity conservation and sustainable development are the possible ways to curtail the impact of climate change. Although, adequate efforts have been made worldwide to tackle the environmental challenges, the adverse effects of climate change are still accelerating and the rate of loss of biodiversity is continuing globally

Monovalent ions modulate the flux through multiple folding pathways of an RNA pseudoknot

The functions of RNA pseudoknots (PKs), which are minimal tertiary structural motifs and an integral part of several ribozymes and ribonucleoprotein complexes, are determined by their structure, stability and dynamics. Therefore, it is important to elucidate the general principles governing their thermodynamics/folding mechanisms. Here, we combine experiments and simulations to examine the folding/unfolding pathways of the VPK pseudoknot, a variant of the Mouse Mammary Tumor Virus (MMTV) PK involved in ribosomal frameshifting. Fluorescent nucleotide analogs (2-aminopurine and pyrrolocytidine) placed at different stem/loop positions in the PK, and laser temperature-jump approaches serve as local probes allowing us to monitor the order of assembly of VPK with two helices with different intrinsic stabilities. The experiments and molecular simulations show that at 50 mM KCl the dominant folding pathway populates only the more stable partially folded hairpin. As the salt concentration is increased a parallel folding pathway emerges, involving the less stable hairpin structure as an alternate intermediate. Notably, the flux between the pathways is modulated by the ionic strength. The findings support the principle that the order of PK structure formation is determined by the relative stabilities of the hairpins, which can be altered by sequence variations or salt concentrations. Our study not only unambiguously demonstrates that PK folds by parallel pathways, but also establishes that quantitative description of RNA self-assembly requires a synergistic combination of experiments and simulations.Comment: Supporting Information include