Early time-locked gamma response and gender specificity

Cataloged from PDF version of article.The aim was to investigate whether gender is a causative factor in the gamma status according to which some individuals respond with time-locked, early gamma response, G+, while the others do not show this response, G-. The sample consisted of 42 volunteer participants (between 19 and 37 years of age with at least 9 years of education). There were 22 females and 20 males. Data were collected under the oddball paradigm. Auditory stimulation (10 ms r/f time, 50 ms duration, 65 dB SPL) consisted of target (2000 Hz; p = .20) stimuli that occurred randomly within a series of standard stimuli (1000 Hz; p = .80). Gamma responses were studied in the amplitude frequency characteristics, in the digitally filtered event-related potentials (f-ERPs) and in the distributions which were obtained using the recently developed time-frequency component analysis (TFCA) technique. Participants were classified into G+ and G- groups with a criterion of full agreement between the results of an automated gamma detection technique and expert opinion. The 2 × 2 × 2 ANOVA on f-ERPs and 2 × 2 × 2 multivariate ANOVA on TFCA distributions showed the main effect of gamma status and gender as significant, and the interaction between gamma status and gender as nonsignificant. Accordingly, individual difference in gamma status is a reliable phenomenon, but this does not depend on gender. There are conflicting findings in the literature concerning the effect of gender on ERP components (N100, P300). The present study showed that if the gamma status is not included in research designs, it may produce a confounding effect on ERP parameters. © 2005 Elsevier B.V. All rights reserved

Susceptibility testing of Haemophilus influenzae— an international collaborative study in quality assessment

In order to compare the prevalence of antibiotic resistance in different geographical areas, it is necessary to ensure that agreement is achieved between laboratories on the assignment of strains to ‘susceptible' and ‘resistant' categories. An international quality assessment study, involving 15 laboratories in eight countries, was performed to investigate the standard of performance of the susceptibility testing of Haemophilus influenzae. One hundred and fifty strains of H. influenzae were distributed from the London Hospital Medical College (LHMC) to all laboratories who were asked to test the susceptibility of the strains to ampicillin, chloramphenicol, tetracycline, trimethoprim, cephalosporins and ciprofloxacin. Laboratories were also asked to provide the details of methodology to test the susceptibility. Significant discrepancy between the LHMC and the participating laboratories appeared in the detection of resistance to ampicillin (especially β-lactamase-negative strains resistant to ampicillin) as well as the assignment of susceptibility and resistance to chloramphenicol, tetracycline and trimethoprim. Often these reflected the use of inappropriate breakpoints which led to erroneous assignment of susceptibility. Other variations including disc content, medium and supplement, inoculum as well as failure to measure zone sizes properly also led to some repeating anomalie

A Large Hadron Electron Collider at CERN

This document provides a brief overview of the recently published report on the design of the Large Hadron Electron Collider (LHeC), which comprises its physics programme, accelerator physics, technology and main detector concepts. The LHeC exploits and develops challenging, though principally existing, accelerator and detector technologies. This summary is complemented by brief illustrations of some of the highlights of the physics programme, which relies on a vastly extended kinematic range, luminosity and unprecedented precision in deep inelastic scattering. Illustrations are provided regarding high precision QCD, new physics (Higgs, SUSY) and electron-ion physics. The LHeC is designed to run synchronously with the LHC in the twenties and to achieve an integrated luminosity of O(100) fb$^{-1}$. It will become the cleanest high resolution microscope of mankind and will substantially extend as well as complement the investigation of the physics of the TeV energy scale, which has been enabled by the LHC

Compressive sensing-based robust off-the-grid stretch processing

Classical stretch processing (SP) obtains high range resolution by compressing large bandwidth signals with narrowband receivers using lower rate analogue-to-digital converters. SP achieves the resolution of the large bandwidth signal by focusing into a limited range window, and by deramping in the analogue domain. SP offers moderate data rate for signal processing for high bandwidth waveforms. Furthermore, if the scene in the examined window is sparse, compressive sensing (CS)-based techniques have the potential to further decrease the required number of measurements. However, CS-based reconstructions are highly affected by model mismatches such as targets that are off-the-grid. This study proposes a sparsity-based iterative parameter perturbation technique for SP that is robust to targets off-the-grid in range or Doppler. The error between reconstructed and actual scenes is measured using Earth mover's distance metric. Performance analyses of the proposed technique are compared with classical CS and SP techniques in terms of data rate, resolution and signal-to-noise ratio. It is shown through simulations that the proposed technique offers robust and high-resolution reconstructions for the same data rate compared with both classical SP- and CS-based techniques. © 2017, The Institution of Engineering and Technology

A novel STFT implementation for the analysis of non-stationary jammer interference

A novel adaptive short-time Fourier transform (STFT) implementation for the analysis of non-stationary multi-component jammer signals is introduced. The proposed time-frequency distribution is the fusion of optimum STFTs of individual signal components that are based on the recently introduced generalized time-bandwidth product (GTBP) definition. The GTBP optimal STFTs of the components are combined through thresholding and obtaining the individual component support images, which are related with the corresponding GTBP optimal STFTs

Generalization of time-frequency signal representations to joint fractional Fourier domains

The 2-D signal representations of variables rather than time and frequency have been proposed based on either Hermitian or unitary operators. As an alternative to the theoretical derivations based on operators, we propose a joint fractional domain signal representation (JFSR) based on an intuitive understanding from a time-frequency distribution constructing a 2-D function which designates the joint time and frequency content of signals. The JFSR of a signal is so designed that its projections on to the defining joint fractional Fourier domains give the modulus square of the fractional Fourier transform of the signal at the corresponding orders. We derive properties of the JFSR including its relations to quadratic time-frequency representations and fractional Fourier transformations. We present a fast algorithm to compute radial slices of the JFSR

Good outcome in patients with normal-pressure hydrocephalus and factors indicating poor prognosis

Object The authors set out to describe the outcome in a subgroup of patients with normal-pressure hydrocephalus (NPH) in whom prognostic factors were poor. This subgroup of patients who had received shunts was selected according to strict criteria. Methods From a cohort of 56 patients with NPH in whom shunts were placed, the authors selected a subgroup with four of the factors traditionally considered to indicate poor prognosis: idiopathic type, cortical atrophy, longstanding symptoms, and presence of dementia in addition to old age. Twelve patients met the inclusion criteria. After receiving shunts, 92% of the patients showed clinical improvement on the NPH scale; gait improved in 100% of patients, sphincter control in 90%, and dementia in 33%. Improvement was significant for gait and sphincter control, general NPH score, and most daily life activity scales. No significant differences regarding clinical, cognitive, or functional changes following surgery were found in comparison with the rest of patients (the good prognosis subgroup). Conclusions The clinical condition of patients with NPH who present with traditionally accepted markers of poor prognosis can improve after surgery, especially as regards gait and sphincter control. The authors assert that the presence of these markers should not be considered to be an absolute criterion for ruling out shunt surgery in cases of NPH syndrome

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

Open-system orchestration as a relational source of sensing capabilities: Evidence from a venture association

Research on innovation networks has highlighted the pivotal role that actors with more prominence and power, such as hub firms, may play in orchestrating the activities of other network members along a collective innovation effort. Our study examined the undertheorized, but no less important, type of orchestration that characterizes other organizations, such as business incubators and venture associations, who seek to support the dispersed entrepreneurial efforts of network members. We refer to this type as ‘open-system’ orchestration, as opposed to the commonly studied ‘closed-system’ type performed by hub firms. Our findings reveal how the processes of open-system orchestration differ markedly from those of closed-system orchestration, and detail how these processes influence the micro-foundations of network members’ sensing capabilities. By doing so, we also offer empirical substantiation and theoretical elaboration to the idea that dynamic capabilities might not reside exclusively inside firms, but could be co-created relationally with other parties in the business ecosystem