A quantitative analysis of inter-island telephony traffic in the Pacific Basin Region (PBR)

As part of NASA's continuing assessment of future communication satellite requirements, a study was conducted to quantitatively scope current and future telecommunication traffic demand in the South Pacific Archipelagos. This demand was then converted to equivalent satellite transponder capacities. Only inter-island telephony traffic for the Pacific Basin Region was included. The results show that if all this traffic were carried by a satellite system, one-third of a satellite transponder would be needed to satisfy the base-year (1976-1977) requirement and about two-thirds of a satellite transponder would be needed to satisfy the forecasted 1985 requirement

Nature of the Coast Batholith, Southeastern Alaska: Are there Archean analogs

The comparison of Phanerozoic Andean margins and their possible Archean analogs was made. Geochemical and isotopic data was presented for the episodic intrusion of the elongate, continental margin Coast batholith of southeastern Alaska and British Columbia. The batholith was characterized as having been formed in direct response to subduction in accreted terranes of oceanic or slope origin. It was concluded that there were good analogs of the Coast batholith in Archean plutonic suites

Magnetic buoyancy in simulated galactic discs with a realistic circum galactic medium

We present simulations of isolated disc galaxies in a realistic environment performed with the Tree-SPMHD-Code Gadget-3. Our simulations include a spherical circum-galactic medium (CGM) surrounding the galactic disc, motivated by observations and the results of cosmological simulations. We present three galactic models with different halo masses between 10e10 Msol and 10e12 Msol, and for each we use two different approaches to seed the magnetic field, as well as a control simulation without a magnetic field. We find that the amplification of the magnetic field in the centre of the disc leads to a biconical magnetic outflow of gas that magnetizes the CGM. This biconical magnetic outflow reduces the star formation rate (SFR) of the galaxy by roughly 40 percent compared to the simulations without magnetic fields. As the key aspect of our simulations, we find that small scale turbulent motion of the gas in the disc leads to the amplification of the magnetic field up to tens of 10e-6 G, as long as the magnetic field strength is low. For stronger magnetic fields turbulent motion does not lead to significant amplification but is replaced by an alpha-omega dynamo. The occurance of a small scale turbulent dynamo becomes apparent through the magnetic power spectrum and analysis of the field lines' curvature. In accordance with recent observations we find an anti-correlation between the spiral structure in the gas density and in the magnetic field due to a diffusion term added to the induction equation.Comment: 22 pages, 16 figures, submitted to MNRA

Declining rotation curves at z=2z=2 in Λ\LambdaCDM galaxy formation simulations

Selecting disk galaxies from the cosmological, hydrodynamical simulation Magneticum Pathfinder we show that almost half of our poster child disk galaxies at $z=2$ show significantly declining rotation curves and low dark matter fractions, very similar to recently reported observations. These galaxies do not show any anomalous behavior, reside in standard dark matter halos and typically grow significantly in mass until $z = 0$, where they span all morphological classes, including disk galaxies matching present day rotation curves and observed dark matter fractions. Our findings demonstrate that declining rotation curves and low dark matter fractions in rotation dominated galaxies at $z=2$ appear naturally within the $\Lambda$CDM paradigm and reflect the complex baryonic physics, which plays a role at the peak epoch of star-formation. In addition, we find some dispersion dominated galaxies at $z=2$ which host a significant gas disk and exhibit similar shaped rotation curves as the disk galaxy population, rendering it difficult to differentiate between these two populations with currently available observation techniques.Comment: 6 pages, 4 figures, ApJ Letters in press, www.magneticum.or

An improved SPH scheme for cosmological simulations

We present an implementation of smoothed particle hydrodynamics (SPH) with improved accuracy for simulations of galaxies and the large-scale structure. In particular, we combine, implement, modify and test a vast majority of SPH improvement techniques in the latest instalment of the GADGET code. We use the Wendland kernel functions, a particle wake-up time-step limiting mechanism and a time-dependent scheme for artificial viscosity, which includes a high-order gradient computation and shear flow limiter. Additionally, we include a novel prescription for time-dependent artificial conduction, which corrects for gravitationally induced pressure gradients and largely improves the SPH performance in capturing the development of gas-dynamical instabilities. We extensively test our new implementation in a wide range of hydrodynamical standard tests including weak and strong shocks as well as shear flows, turbulent spectra, gas mixing, hydrostatic equilibria and self-gravitating gas clouds. We jointly employ all modifications; however, when necessary we study the performance of individual code modules. We approximate hydrodynamical states more accurately and with significantly less noise than standard SPH. Furthermore, the new implementation promotes the mixing of entropy between different fluid phases, also within cosmological simulations. Finally, we study the performance of the hydrodynamical solver in the context of radiative galaxy formation and non-radiative galaxy cluster formation. We find galactic disks to be colder, thinner and more extended and our results on galaxy clusters show entropy cores instead of steadily declining entropy profiles. In summary, we demonstrate that our improved SPH implementation overcomes most of the undesirable limitations of standard SPH, thus becoming the core of an efficient code for large cosmological simulations.Comment: 21 figures, 2 tables, accepted to MNRA

SYNTHESIS OF GADOLINIUM-DOXORUBICIN PRODRUG CARRYING FUNCTIONAL NANOCERIA FOR THE TARGETED DRUG DELIVERY AND CANCER TREATMENT

The main focus of this research was the development of a polymer-coated nanoceria (PNC) platform to be used as a drug delivery system. Water-dispersible PNC is synthesized using a water-based alkaline precipitation method. Cerium nitrate hexahydrate and poly (acrylic acid) are used for the preparation of PNC. The synthesized PNC was characterized using ZETA, and UV- Vis characterization techniques. Polyacrylic acid (PAA)-coated cerium oxide nanoparticles fabricated for the targeted combination therapy of TNBC (MDA-MB-231) and MCF-7. Using EDC/NHS chemistry, the surface carboxylic acid groups of nanoceria was designed and synthesized with ICAM-1 antibody to target ICAM-1 overexpressing TNBC. Next, doxorubicin with gadolinium as a Doxo-Gd prodrug was used as a therapeutic agent. The dialysis technique was used for the purification purpose of nanoparticles to remove unreacted particles. Doxo-Gd provided activable MR imaging and treatment of cancer. The cytotoxicity of the formulated PNC was evaluated using cell-based MTT assays. The cell viability and cell internalization assays were performed using TNBC & MCF-7 cells. The detailed synthetic protocols, characterization data, and experimental results are presented in this work