552 research outputs found

    Corporate social responsibility and sustainable development

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    Corporate social responsibility (CSR) meaning the active and voluntary contribution of firms to enhance welfare, is achieving a greater importance in Business administration as an intangible asset which management generates competitive advantages and promotes sustainable development. This work indentifies similarities between CSR management and Intellectual Capital management, this one meant as those activities which help us to manage the knowledge of the firm. Our aim is that firms understand the importance of considering CSR as a corporate strategy that enhances the value of the organization, and that they become conscious about its efficiency and efficacy.peer-reviewe

    The Cretaceous-Tertiary boundary marine extinction and global primary productivity collapse

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    The extinction of marine phyto-and zoo-plankton across the K-T boundary has been well documented. Such an event may have resulted in decreased photosynthetic fixation of carbon in surface waters and a collapse of the food chain in the marine biosphere. Because the vertical and horizontal distribution of the carbon isotopic composition of total dissolved carton (TDC) in the modern ocean is controlled by the transfer of organic carbon from the surface to deep reservoirs, it follows that a major disruption of the marine biosphere would have had a major effect on the distribution of carbon isotopes in the ocean. Negative carbon isotope excursions have been identified at many marine K-T boundary sequences worldwide and are interpreted as a signal of decreased oceanic primary productivity. However, the magnitude, duration and consequences of this productivity crisis have been poorly constrained. On the basis of planktonic and benthic calcareous microfossil carbon isotope and other geochemical data from DSDP Site 577 located on the Shatsky Rise in the north-central Pacific, as well as other sites, researchers have been able to provide a reasonable estimate of the duration and magnitude of this event

    Le Kouri : race bovine du lac Tchad. I. Introduction générale à son étude zootechnique et biochimique : origines et écologie de la race

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    Les auteurs présentent de façon détaillée la race des taurins Kouris, bovins du lac Tchad. Cette première étude est l'introduction pour l'ensemble des travaux qui visent à éclairer les divers aspects zootechniques et biochimiques de cette race, connue depuis longtemps déjà et qui est étroitement liée au milieu aquatique du lac Tchad. Le but poursuivi est de ne pas laisser disparaître un maillon, sans doute essentiel, dans la phylogénie des races bovines et de tirer profit rapidement des propriétés les plus intéressantes de la race : production laitière, production de viande de qualité et propriétés des métis de 1re ou de 2e génération. Après l'étude écologique de l'aire géographique, le type caractéristique est décrit ainsi que ses propriétés économiques. Le mode d'élevage et la pathologie sont largement détaillés. De nombreuses raisons plaident actuellement pour le maintien et la sélection des bovins Kouris purs. (Résumé d'auteur

    Six simple guidelines for introducing new genera of fungi

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    We formulate five guidelines for introducing new genera, plus one recommendation how to publish the results of scientific research. We recommend that reviewers and editors adhere to these guidelines. We propose that the underlying research is solid, and that the results and the final solutions are properly discussed. The six criteria are: (1) all genera that are recognized should be monophyletic; (2) the coverage of the phylogenetic tree should be wide in number of species, geographic coverage, and type species of the genera under study; (3) the branching of the phylogenetic trees has to have sufficient statistical support; (4) different options for the translation of the phylogenetic tree into a formal classification should be discussed and the final decision justified; (5) the phylogenetic evidence should be based on more than one gene; and (6) all supporting evidence and background information should be included in the publication in which the new taxa are proposed, and this publication should be peer-reviewed

    Parental Perceptions of Child Neglect and Triggering Factors

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    Child neglect is the most widely reported and substantiated form of maltreatment in the United States. Although the federal government establishes the minimal definition, acts, and behaviors that comprise child neglect, there are discrepancies at the national, state, local, and organizational levels in how child neglect is defined. The purpose of this study was to increase the understanding of how parents perceive the definition of child neglect and the factors they believe trigger it. Using the social cognitive theory as the theoretical foundation, the generic qualitative research design was used to explore the perceptions of child neglect and beliefs of factors and triggers of child neglect of 15 parents. The data were collected through semi-structured interviews using open-ended questions. The data were subsequently analyzed using the thematic inductive data analysis process and was recorded, hand-coded, categorized, and compiled into themes. Four central themes emerged from the data in relation to the research questions: perceived definitions of child neglect, inconsistencies in defining child neglect, perceived factors of child neglect, and perceived triggers of child neglect. A total of 10 subthemes were also developed, exploring the perceptions of parents on the definition of child neglect and the factors parents believe trigger child neglect. The findings may contribute to positive social change by being useful for social service providers to gain a better understanding of the perceptions of parents regarding child neglect and what factors they believe contribute to and trigger child neglect so that more effective education, prevention, and intervention programs may be developed

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    Étude structurale de la fructoselysine 6-kinase d’Escherichia coli : reconnaissance de substrats et mécanisme enzymatique

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    Quelques enzymes sont connus pour déglyquer les kétoamines résultants de la réaction de Maillard entre des sucres et des amines primaires. Il a été démontré qu’Escherichia coli possède un opéron afin de métaboliser la fructoselysine. La fructoselysine 6-kinase, de la famille des PfkB, initie le processus de déglycation permettant l’utilisation ultérieure du glucose-6-P par la bactérie. La résolution de la structure de la FL6K par cristallographie et diffraction des rayons X a permis d’identifier son site actif en présence d’ATP, d’ADP et d’AMP-PNP. La modélisation de la fructoselysine au site actif de la kinase a permis d’identifier des résidus pouvant être importants pour sa liaison et son mécanisme enzymatique. De plus, les résultats de cinétique suggèrent que le mécanisme utilisé par la FL6K semble passer par un état ternaire de type SN2. Des modifications structurales à la FL6K pourraient permettre d’augmenter la taille des substrats afin de permettre ultimement la déglycation de protéines.Some enzymes have been found to deglycate the products of the Maillard reaction between sugars and primary amines: ketoamines. An operon is found in Escherichia coli that allows the growth on fructoselysine media. The deglycation process is done by a kinase and a “deglycase”. The fructoselysine 6-kinase, a member of the PfkB family, phosphorylates its substrate on the sixth carbon to initiate the metabolism of fructoselysine. Here are presented x-ray crystallography structures obtained for the fructoselysine 6-kinase in its native form and bound with ATP, ADP and AMP-PNP. The active site of the kinase has been determined, and modelisation of fructoselysine allowed identification of some residues that might be important for the specific binding of the substrate and the enzymatic mechanism. Kinetic results tend to suggest a SN2 mechanism for the phosphorylation catalyzed by the enzyme. Structural modifications of the FL6K could help to increase the size of the substrates recognized by the enzyme until it binds glycated proteins
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