EMAIL VERIFICATION SERVICE USING BLOCKCHAIN

Current email security solutions depend on various attributes to reduce the chances that a given email (mail) is likely to be a threat. However, current solutions make it relatively easy to target corporate organizations with a Business Email Compromise (BEC) attack. A BEC attack is a non-malicious mail which defrauds key people in organizations into performing, for example, wire transfers meant for the suppliers or partners abroad. The U.S. Federal Bureau of Investigation (FBI) has been tracking BEC, also known as email fraud and email account compromise (EAC), domestically and globally since October 2013. The recent trends related to fraudulent wire transfers and unauthorized disclosures of employee data are alarming: Total identified global exposed losses now exceed $12.5 billion (up from$5.3 billion in December 2016). More than 30,000 victim complaints were submitted between June 2016 and May 2018 via the recently launched Internet Crime Complaint Center (IC3) compliant form. BEC scams targeting the real estate sector rose more than 1,100% between 2015 and 2017. Wage and tax documentation BEC scams extend the threat beyond wire transfers and continue to grow. The US Internal Revenue Service (IRS) indicated it received approximately 900 reports of Form W-2 scams in 2017 (compared to just over 100 reports in 2016). The problem is that there is no absolute way to understand if a mail was sent from a particular sender to a group of recipients

Subject-variability effects on micron particle deposition in human nasal cavities

Validated computer simulations of the airflow and particle dynamics in human nasal cavities are important for local, segmental and total deposition predictions of both inhaled toxic and therapeutic particles. Considering three, quite different subject-specific nasal airway configurations, micron-particle transport and deposition for low-to-medium flow rates have been analyzed. Of special interest was the olfactory region from which deposited drugs could readily migrate to the central nervous system for effective treatment. A secondary objective was the development of a new dimensionless group with which total particle deposition efficiency curves are very similar for all airway models, i.e., greatly reducing the impact of intersubject variability. Assuming dilute particle suspensions with inhalation flow rates ranging from 7.5 to 20 L/min, the airflow and particle-trajectory equations were solved in parallel with the in-house, multi-purpose Alya program at the Barcelona Supercomputing Center. The geometrically complex nasal airways generated intriguing airflow fields where the three subject models exhibit among them both similar as well as diverse flow structures and wall shear stress distributions, all related to the coupled particle transport and deposition. Nevertheless, with the new Stokes-Reynolds-number group, , the total deposition-efficiency curves for all three subjects and flow rates almost collapsed to a single function. However, local particle deposition efficiencies differed significantly for the three subjects when using particle diameters = 2, 10, and . Only one of the three subject-specific olfactory regions received, at relatively high values of the inertial parameter , some inhaled microspheres. Clearly, for drug delivery to the brain via the olfactory region, a new method of directional inhalation of nanoparticles would have to be implemented.The authors acknowledge Dr. Rick Corley and colleagues at Pacific Northwest National Laboratory for providing the subject B nasal surface geometry and Dr. Edgar Matida and Dr. Matthew Johnson at Carleton University for providing the subject C nasal surface geometryPeer ReviewedPostprint (published version

A comparison of Mallampati scoring, upper lip bite test and sternomental distance in predicting difficult intubation

Background: Difficult or failed tracheal intubation has been identified as one of the most important causes of death or permanent brain damage during anaesthesia. The present study has aimed to compare modified Mallampati score, Upper lip bite test and sternomental distance for predicting difficult intubation in adult patients.Methods: In this study 199 patients aged 18-60 years were recruited who were undergoing elective surgeries requiring endotracheal intubation. All patients were evaluated using modified Mallampati score, upper lip bite test and sternomental distance. Laryngoscopy was assessed by an attending anaesthesiologist blinded to the measurements and graded according to Cormack and Lehane’s grading system. Specificity, sensitivity, predictive positive value (PPV), predictive negative value (PNV), accuracy and agreement with larygoscopic grading were calculated for each parameter.Results: Specificities for modified Mallampati, upper lip bite test and sternomental distance were 65.6, 98.9 and 94%, respectively. All the tests had a NPV more than 90%, indicating that, these tests can be good predictors of easy intubation. Sternomental distance showed greatest agreement with laryngoscopic grading (kappa = 0.536, P<0.001) as well as maximum area under the ROC curve (0.955).Conclusions: The high specificity, NPV, PPV and accuracy of sternomental distance compared to other tests makes it the single best test in predicting difficulty intubation. However, a combination of all three tests was found to be more sensitive and had higher discriminative power compared to any single test alone

Human health and water quality impact assessment

Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2002.Includes bibliographical references (p. 70-71).by Arun Varghese.M.Eng

A study to assess the self care ability and mental status among schizophrenic patients undergoing occupational therapy in a selected psychiatric nursing home, Kottayam, Kerala.

A study to assess the self care ability and mental status among schizophrenic patients undergoing occupational therapy in selected psychiatric nursing home, Kerala, is submitted as the partial fulfilment of the requirement for the degree of Master of Science in Nursing. It was done by 30093642 from Annai J.K.K. Sampoorani Ammal College under the Tamilnadu Dr.M.G.R. Medical University, Chennai, April 2011. The objectives of the study were to describe the self care ability and mental status of schizophrenic patients in relation to occupational therapy, to test the association between self care ability and mental status among schizophrenic patients in relation to occupational therapy and to test the association between self care ability, mental status and selected factors among schizophrenic patients in relation to occupational therapy. The Research Hypothesis includes H1-There will be a significant correlation between self care ability and mental status among schizophrenic patients , H2- There will be significant association between self care ability and mental status among schizophrenic patients in relation to occupational therapy, H3-There will be significant association between self care ability and selected factors among schizophrenic patients undergoing occupational therapy and H4-There will be significant association between Mental status and selected factors of schizophrenic patients in relation to occupational therapy. The review of literature was collected under the following heading: (1) Studies related to Occupational Therapy and Schizophrenic patients, (2) Studies related to Self care Ability of Schizophrenic patients and occupational therapy and Studies related to Mental Status of Schizophrenic patients and occupational therapy. The conceptual framework adopted for the study was Three Tier work related social skills [Hector Tsang,1996].The Research Design used for the study was Descriptive design. The Setting of the study was Nazareth Asram (a psychiatric nursing home, Vazhoor), Kottayam, Kerala. The sample size was 108 Schizophrenic patients undergoing Occupational therapy selected by Purposive Sampling . The tool were developed from Allen Cognitive Scale for Daily Living and Mini Mental Status Examination (Folstein,1975) was Modified and Validated. The Tool was Reliable and Feasible. The reliability of the tool was established by Inter rater Reliability, the Coefficient of Correlation was r=0.87, found to be highly reliable. The findings of the study revealed there was significant positive co-relation between self care ability and mental status of schizophrenic patients in relation to occupational therapy. There was significant association between self care ability, mental status and selected factors in terms of duration of Occupational therapy and type of Schizophrenia. The study concluded that as the duration of Occupational therapy increases majority of the Schizophrenic patients showed improvement in Self care ability and mental status. So that the Mental Health Nurses must be a part and parcel of promoting Social productivity of schizophrenic patients through Occupational skill training

Effectiveness of Hatha Yoga on Stress and Anxiety among Adolescents at Selected Colleges, Salem

A study was conducted to determine the effectiveness of Hatha Yoga on stress and anxiety among adolescents at selected colleges, Salem. The design adopted was True experimental pre test post test control group design. The settings of the study were Vinayaka Missions Kirupananda Variyar Engineering College, Salem and AVS Engineering College, Salem. 60 samples, (30 in experimental group and 30 in control group) were drawn through simple random sampling technique using lottery method. The level of stress and anxiety were assessed using Modified Perceived Stress Scale and Hamilton’s Anxiety Rating Scale respectively. The investigator demonstrated Hatha yoga and the samples practiced it for 30 minutes every day in the morning for 21 consecutive days. Post test was done on the 29th day of intervention. The data gathered was analyzed with the help of descriptive and inferential statistics. The findings revealed that in experimental group, the mean pre test level of stress decreased from 38.67 (SD=11.30) to 26.13 (SD=6.74) at post test with a mean difference of 12.54 whereas the mean pre test level of anxiety decreased from 17.43 (SD=7.20) to 11.17 (SD=4.20) at post test with a mean difference of 6.26. The paired ‘t’ value at p≤ 0.05 level for stress and anxiety were 8.06 and 7.24 respectively which is significantly higher than the table value 2.05. Hence H1 was retained. In experimental group, the mean post test level of stress was 26.13+6.74 and in control group, it was 36.37+11.01 with a mean difference of 10.24 whereas the mean post test level of anxiety was 11.17+ 4.20 and that for control group was 16.37 +7.50 with a mean difference of 5.20. There is significant difference between the scores of experimental and control group computed through independent ‘t’ test at p≤ 0.05 level (t=4.341 for stress and t=3.312 for anxiety). Hence H2 was retained. No significant association was found between level of stress and anxiety with their demographic variables in experimental group. However, there was a significant association between level of stress and the demographic variable family income in control group (χ2 =8.82 and table value = 7.82). Hence H3 was retained only for the above mentioned variable. This study concludes that Hatha Yoga is a cost effective, easy to practice non pharmacological method in reducing the level of stress and anxiety in adolescents

Optically processed Kannada script realization with Siamese neural network model

Optical character recognition (OCR) is a technology that allows computers to recognize and extract text from images or scanned documents. It is commonly used to convert printed or handwritten text into machine-readable format. This Study presents an OCR system on Kannada Characters based on siamese neural network (SNN). Here the SNN, a Deep neural network which comprises of two identical convolutional neural network (CNN) compare the script and ranks based on the dissimilarity. When lesser dissimilarity score is identified, prediction is done as character match. In this work the authors use 5 classes of Kannada characters which were initially preprocessed using grey scaling and convert it to pgm format. This is directly input into the Deep convolutional network which is learnt from matching and non-matching image between the CNN with contrastive loss function in Siamese architecture. The Proposed OCR system uses very less time and gives more accurate results as compared to the regular CNN. The model can become a powerful tool for identification, particularly in situations where there is a high degree of variation in writing styles or limited training data is available

N-[(E)-Quinoxalin-2-ylmethyl­idene]-1H-indazol-5-amine

In the title mol­ecule, C16H11N5, the mean planes of the quinoxaline and indazole fragments form a dihedral angle of 10.62 (5)°. In the crystal, weak inter­molecular N—H⋯N hydrogen bonds link the mol­ecules into zigzag chains extending in the [001] direction. The crystal packing also exhibits π–π inter­actions [centroid–centroid distances of 3.7080 (2) and 3.8220 (5) Å], which form stacks of the mol­ecules parallel to the a axis

(Z)-2-Amino-3-[(E)-benzyl­ideneamino]but-2-enedinitrile

The asymmetric unit of the title compound, C11H8N4, contains two independent mol­ecules. In the crystal structure, inter­molecular N—H⋯N hydrogen bonds link mol­ecules into ribbons extended in the [100] direction

"Keep it simple - a lesson from COVID-19" : highlighting the utility of chest X-rays in ARDS-associated illnesses through the Zonal Scoring System

Purpose: The post-pandemic era calls for appropriate literature on chest X-ray score cut-offs, enabling swift categorization and faster radiological reporting of patients with acute respiratory distress syndrome (ARDS)-like illnesses, hence prompting healthcare equity in low-resource centres where extortionate modalities of imaging such as computed tomography (CT) are unavailable. In this study, we aim to bridge the literature gap using the versatile zonal scoring system. Material and methods: This retrospective cohort study uses data from 751 COVID-19 RT-PCR+ patients. Concordantchest radiograph (CXR) scores were reported, and inter-rater reliability was measured using kappa indices. receiver operating characteristic curves were used to establish cut-off scores for the outcomes of interest: mild or severe disease, admission to an intensive care unit (ICU), and intubation. Categorical data were expressed using means and percentages, and c2 or t-tests were used for comparison at an a level of 0.05. Unadjusted odds ratios for each outcome of interest vs. CXR score and comorbidity were then calculated using binary logistic regression. Results: CXR findings included infiltrates (46.07%), pleural effusions (7.05%), consolidation and fibrosis (4.43%), pneumothoraces (2.71%), and cardiomegaly (2.26%). Most patients had an index CXR score of 0 (54.19%). The index cut-off score of ≤ 1 (82.95, 81.68) was established for mild disease, ≥ 4 for severe disease (85.71, 83.99), ≥ 3 for ICU admission (86.90, 71.91), and ≥ 4 for intubation (87.61, 72.90). Hypertension, type 2 diabetes mellitus, hypothyroidism, history of ischaemic heart disease, and history of tuberculosis were independent risk factors for a high CXR index score, intubation, and ICU admission. Conclusions: CXR scores can be effectively used in low-resource settings for triaging patients, maintaining records, and disease prognostication