A global action agenda for turning the tide on fatty liver disease

Background and Aims: Fatty liver disease is a major public health threat due to its very high prevalence and related morbidity and mortality. Focused and dedicated interventions are urgently needed to target disease prevention, treatment, and care. Approach and Results: We developed an aligned, prioritized action agenda for the global fatty liver disease community of practice. Following a Delphi methodology over 2 rounds, a large panel (R1 n = 344, R2 n = 288) reviewed the action priorities using Qualtrics XM, indicating agreement using a 4-point Likert-scale and providing written feedback. Priorities were revised between rounds, and in R2, panelists also ranked the priorities within 6 domains: epidemiology, treatment and care, models of care, education and awareness, patient and community perspectives, and leadership and public health policy. The consensus fatty liver disease action agenda encompasses 29 priorities. In R2, the mean percentage of “agree” responses was 82.4%, with all individual priorities having at least a super-majority of agreement (> 66.7% “agree”). The highest-ranked action priorities included collaboration between liver specialists and primary care doctors on early diagnosis, action to address the needs of people living with multiple morbidities, and the incorporation of fatty liver disease into relevant non-communicable disease strategies and guidance. Conclusions: This consensus-driven multidisciplinary fatty liver disease action agenda developed by care providers, clinical researchers, and public health and policy experts provides a path to reduce the prevalence of fatty liver disease and improve health outcomes. To implement this agenda, concerted efforts will be needed at the global, regional, and national levels.publishedVersio

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

BackgroundArtificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain. We assessed awareness, use, perceived value, barriers, and policy priorities among hepatology clinicians in the region.MethodsA cross-sectional online survey targeted hepatologists and gastroenterologists across 17 MENA countries. The survey assessed clinical and research applications of AI, perceived benefits, clinical and research use, barriers, ethical considerations, and institutional readiness. Descriptive statistics and thematic analysis were performed.ResultsOf 285 invited professionals, 236 completed the survey (response rate: 82.8%). While 73.2% recognized the transformative potential of AI, only 14.4% used AI tools daily, primarily for imaging analysis and disease prediction. AI tools were used in research by 39.8% of respondents, mainly for data analysis, manuscript writing assistance, and predictive modeling. Major barriers included inadequate training (60.6%), limited AI tool access (53%), and insufficient infrastructure (53%). Ethical concerns focused on data privacy, diagnostic accuracy, and over-reliance on automation. Despite these challenges, 70.3% expressed strong interest in AI training., and 43.6% anticipating routine clinical integration within 1–3 years.ConclusionMENA hepatologists are optimistic about AI but report limited routine use and substantial readiness gaps. Priorities include scalable training, interoperable infrastructure and standards, clear governance with human-in-the-loop safeguards, and region-specific validation to enable safe, equitable implementation

The role of accounting and auditing in achieving industrial competitiveness and improving economic growth: دور المحاسبة والتدقيق في تحقيق القدرة التنافسية الصناعية وتحسين النمو الاقتصادي

يتزايد الاهتمام في الوقت الحاضر بأخلاقيات الأعمال، فبعد أن كانت الكفاءة هي مركز الاهتمام الوحيد والربح هو الهدف الأساسي والمسؤولية الوحيدة للأعمال، أصبحت الأخلاقيات تحظى بالاهتمام ويعاد صياغات الأهداف والسياسات بطريقة تبرز المسؤولية الأخلاقية لمؤسسات الأعمال، وتأتي هذه الورقة البحثية لإبراز أهمية المحاسبة كمدخل أخلاقي في تحقيق وخلق ميزة تنافسية للمؤسسات في وقت نجد الوصول والحفاظ على هذه الميزة من غاية الصعوبة، وقد توصلت الدراسة إلى أهمية المحاسبة كمدخل أخلاقي من خلال المسؤولية الاجتماعية وجودة المعلومات المحاسبية في خلق ميزة تنافسية من ناحية الجودة وتخفيض التكاليف.  At the present time, there is growing interest in business ethics. Since efficiency is the sole focus of attention and profit is the primary objective and sole responsibility of business, ethics has become an interest and redefined objectives and policies in a way that highlights the ethical responsibility of business. This paper highlights the importance of accounting as a moral input in achieving And the creation of a competitive advantage for institutions at the time of finding and maintaining this feature is very difficult, the study has reached the importance of accounting as a moral input through social responsibility and the quality of accounting information in creating a competitive advantage Quality and lower costs in terms

Hybrid sliding mode observer for uncertain linear switching system with actuator faults

This paper investigates the problem of designing a hybrid sliding mode observer for mode identification and actuator fault reconstruction, applicable for a class of linear switching systems. For each operating mode constituting the whole system, only one observer is doomed to accomplish the two aforementioned tasks in the presence of exogenous disturbances. The method uses [Formula: see text] concept in the design of the sliding motion so that the effect of uncertainties on the residuals generation for mode recognition and on the reconstruction of the actuator faults will be minimized. Simulation results highlight the efficiency and the effectiveness of the proposed method. </jats:p