Unstable Adams operations on p-local compact groups

A p-local compact group is an algebraic object modelled on the p-local homotopy theory of classifying spaces of compact Lie groups and p-compact groups. In the study of these objects unstable Adams operations, are of fundamental importance. In this paper we define unstable Adams operations within the theory of p-local compact groups, and show that such operations exist under rather mild conditions. More precisely, we prove that for a given p-local compact group G and a sufficiently large positive integer $m$, there exists an injective group homomorphism from the group of p-adic units which are congruent to 1 modulo p^m to the group of unstable Adams operations on

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway

We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of Sw J1644+57. Our main results are as follows. (1) The long-term X-ray light curve of Sw J2058+05 shows a remarkably similar trend to that of Sw J1644+57. After a prolonged power-law decay, the X-ray flux drops off rapidly by a factor of $\gtrsim 160$ within a span of $\Delta$$t$/$t$ $\le$ 0.95. Associating this sudden decline with the transition from super-Eddington to sub-Eddington accretion, we estimate the black hole mass to be in the range of $10^{4-6}$ M$_{\odot}$. (2) We detect rapid ($\lesssim 500$ s) X-ray variability before the dropoff, suggesting that, even at late times, the X-rays originate from close to the black hole (ruling out a forward-shock origin). (3) We confirm using HST and VLBA astrometry that the location of the source coincides with the galaxy's center to within $\lesssim 400$ pc (in projection). (4) We modeled Sw J2058+05's ultraviolet/optical/infrared spectral energy distribution with a single-temperature blackbody and find that while the radius remains more or less constant at a value of $63.4 \pm 4.5$ AU ($\sim 10^{15}$ cm) at all times during the outburst, the blackbody temperature drops significantly from $\sim$ 30,000 K at early times to a value of $\sim$ 15,000 K at late times (before the X-ray dropoff). Our results strengthen Sw J2058+05's interpretation as a tidal disruption event similar to Sw J1644+57.Comment: Replaced with the published version of the manuscrip

Hopf algebras and Markov chains: Two examples and a theory

The operation of squaring (coproduct followed by product) in a combinatorial Hopf algebra is shown to induce a Markov chain in natural bases. Chains constructed in this way include widely studied methods of card shuffling, a natural "rock-breaking" process, and Markov chains on simplicial complexes. Many of these chains can be explictly diagonalized using the primitive elements of the algebra and the combinatorics of the free Lie algebra. For card shuffling, this gives an explicit description of the eigenvectors. For rock-breaking, an explicit description of the quasi-stationary distribution and sharp rates to absorption follow.Comment: 51 pages, 17 figures. (Typographical errors corrected. Further fixes will only appear on the version on Amy Pang's website, the arXiv version will not be updated.

Strong Ultraviolet Pulse From a Newborn Type Ia Supernova

Type Ia supernovae are destructive explosions of carbon oxygen white dwarfs. Although they are used empirically to measure cosmological distances, the nature of their progenitors remains mysterious, One of the leading progenitor models, called the single degenerate channel, hypothesizes that a white dwarf accretes matter from a companion star and the resulting increase in its central pressure and temperature ignites thermonuclear explosion. Here we report observations of strong but declining ultraviolet emission from a Type Ia supernova within four days of its explosion. This emission is consistent with theoretical expectations of collision between material ejected by the supernova and a companion star, and therefore provides evidence that some Type Ia supernovae arise from the single degenerate channel.Comment: Accepted for publication on the 21 May 2015 issue of Natur

A methodology for setting practice criteria in healthcare

Practice criteria are an important part of health care and have taken a new prominence in the trend to address quality-of-care issues. Once an organisation makes a commitment to addressing its quality-of- care, it must define 'quality' in operational terms. Practice criteria do just that. The organisation ensures consistent, high-quality services through the correct application of practice criteria. This paper outlines a methodology that has been used in at least three countries to date. Early indications are that it is useful for helping an organisation begin its quality improvement 'journey'.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Performance of GEDI space-borne LiDAR for quantifying structural variation in the temperate forests of South-Eastern Australia

Monitoring forest structural properties is critical for a range of applications because structure is key to understanding and quantifying forest biophysical functioning, including stand dynamics, evapotranspiration, habitat, and recovery from disturbances. Monitoring of forest structural properties at desirable frequencies and cost globally is enabled by space-borne LiDAR missions such as the global ecosystem dynamics investigation (GEDI) mission. This study assessed the accuracy of GEDI estimates for canopy height, total plant area index (PAI), and vertical profile of plant area volume density (PAVD) and elevation over a gradient of canopy height and terrain slope, compared to estimates derived from airborne laser scanning (ALS) across two forest age-classes in the Central Highlands region of south-eastern Australia. ALS was used as a reference dataset for validation of GEDI (Version 2) dataset. Canopy height and total PAI analyses were carried out at the landscape level to understand the influence of beam-type, height of the canopy, and terrain slope. An assessment of GEDI’s terrain elevation accuracy was also carried out at the landscape level. The PAVD profile evaluation was carried out using footprints grouped into two forest age-classes, based on the areas of mountain ash (Eucalyptus regnans) forest burnt in the Central Highlands during the 1939 and 2009 wildfires. The results indicate that although GEDI is found to significantly under-estimate the total PAI and slightly over-estimate the canopy height, the GEDI estimates of canopy height and the vertical PAVD profile (above 25 m) show a good level of accuracy. Both beam-types had comparable accuracies, with increasing slope having a slightly detrimental effect on accuracy. The elevation accuracy of GEDI found the RMSE to be 10.58 m and bias to be 1.28 m, with an R2 of 1.00. The results showed GEDI is suitable for canopy densities and height in complex forests of south-eastern Australia

Modular supramolecular dimerization of optically tunable extended aryl viologens.

Cucurbit[8]uril (CB[8]) mediated assembly of extended aryl viologens (EVs) into optically tunable dimers is reported for the first time. We show that the modular design and synthesis of a new class of π-conjugated viologen derivatives with rigid aromatic or heteroaromatic bridging units as well as electron donating molecular recognition motifs enable their self-assembly into 2 : 2 complexes with CB[8]. The quantitative dimerization process involving these two molecular components in an aqueous solution enables excimer-like interactions between closely packed charged guests giving rise to distinct spectroscopic behavior. The nature of these dimers (CB[8]2·(EV[X]R)2) in the ground and excited states was characterized by NMR, isothermal titration calorimetry, and steady-state spectroscopic measurements

Building trust in rural communities: recruitment and retention strategies in developmental science

BackgroundStudying human development often requires intimate interpersonal queries and interactions with children and families. Such research necessitates moving beyond traditional lab settings to engage participants within their communities for an extended period of time. Building trust is essential for conducting ecologically valid, longitudinal research, particularly when working with diverse and historically underserved populations. Developing effective, practical strategies to foster trust and rapport enhances recruitment, retention, and the overall quality of developmental research. This manuscript examines the recruitment and retention strategies aimed to facilitate trust and engagement in a longitudinal study involving rural participants in Northeast Georgia.MethodologyThe continuum of community engagement model suggests that research recruitment efforts should involve more than direct participant outreach, toward a multifaceted, community-driven approach. The current study employs a mixed-methods framework to evaluate these strategies in fostering trust and participant engagement. Qualitative data was collected from study reflection notes, interviews with extension agents, and participant surveys, alongside quantitative measures tracking enrollment, contacts, referrals, and participant trust.ResultsOur findings suggest that trust-building efforts, including community engagement teams, reciprocal community relationships, family and family-centered environments, and tailored communication strategies, enhanced participant engagement. Referrals emerged as the most effective method for recruitment. Integrating community-driven recruitment methods led to increased referrals and fostered long-term relationships and trust with community partners, but this success was only achieved after establishing connections and building trust within the community.ConclusionAddressing historical mistrust and promoting research inclusivity requires iterative, community-centered approaches. Our study highlights the importance of transparent communication, adaptive recruitment strategies, and sustained community engagement. Findings provide a framework for future research aiming to enhance trust, recruitment, and retention in complex biomedical and behavioral developmental science, ensuring more representative and impactful studies

Species composition, larval habitats, seasonal occurrence and distribution of potential malaria vectors and associated species of Anopheles (Diptera: Culicidae) from the Republic of Korea

<p>Abstract</p> <p>Background</p> <p>Larval mosquito habitats of potential malaria vectors and related species of <it>Anopheles </it>from three provinces (Gyeonggi, Gyeongsangbuk, Chungcheongbuk Provinces) of the Republic of Korea were surveyed in 2007. This study aimed to determine the species composition, seasonal occurrence and distributions of <it>Anopheles </it>mosquitoes. Satellite derived normalized difference vegetation index data (NDVI) was also used to study the seasonal abundance patterns of <it>Anopheles </it>mosquitoes.</p> <p>Methods</p> <p>Mosquito larvae from various habitats were collected using a standard larval dipper or a white plastic larval tray, placed in plastic bags, and were preserved in 100% ethyl alcohol for species identification by PCR and DNA sequencing. The habitats in the monthly larval surveys included artificial containers, ground depressions, irrigation ditches, drainage ditches, ground pools, ponds, rice paddies, stream margins, inlets and pools, swamps, and uncultivated fields. All field-collected specimens were identified to species, and relationships among habitats and locations based on species composition were determined using cluster statistical analysis.</p> <p>Results</p> <p>In about 10,000 specimens collected, eight species of <it>Anopheles </it>belonging to three groups were identified: Hyrcanus Group - <it>Anopheles sinensis</it>, <it>Anopheles kleini</it>, <it>Anopheles belenrae</it>, <it>Anopheles pullus</it>, <it>Anopheles lesteri</it>, <it>Anopheles sineroides</it>; Barbirostris Group - <it>Anopheles koreicus</it>; and Lindesayi Group - <it>Anopheles lindesayi japonicus</it>. Only <it>An. sinensis </it>was collected from all habitats groups, while <it>An. kleini, An. pullus </it>and <it>An. sineroides </it>were sampled from all, except artificial containers. The highest number of <it>Anopheles </it>larvae was found in the rice paddies (34.8%), followed by irrigation ditches (23.4%), ponds (17.0%), and stream margins, inlets and pools (12.0%). <it>Anopheles sinensis </it>was the dominant species, followed by <it>An. kleini, An. pullus </it>and <it>An. sineroides</it>. The monthly abundance data of the <it>Anopheles </it>species from three locations (Munsan, Jinbo and Hayang) were compared against NDVI and NDVI anomalies.</p> <p>Conclusion</p> <p>The species composition of <it>Anopheles </it>larvae varied in different habitats at various locations. <it>Anopheles </it>populations fluctuated with the seasonal dynamics of vegetation for 2007. Multi-year data of mosquito collections are required to provide a better characterization of the abundance of these insects from year to year, which can potentially provide predictive capability of their population density based on remotely sensed ecological measurements.</p

The Essential Toxin: Impact of Zinc on Human Health

Compared to several other metal ions with similar chemical properties, zinc is relatively harmless. Only exposure to high doses has toxic effects, making acute zinc intoxication a rare event. In addition to acute intoxication, long-term, high-dose zinc supplementation interferes with the uptake of copper. Hence, many of its toxic effects are in fact due to copper deficiency. While systemic homeostasis and efficient regulatory mechanisms on the cellular level generally prevent the uptake of cytotoxic doses of exogenous zinc, endogenous zinc plays a significant role in cytotoxic events in single cells. Here, zinc influences apoptosis by acting on several molecular regulators of programmed cell death, including caspases and proteins from the Bcl and Bax families. One organ where zinc is prominently involved in cell death is the brain, and cytotoxicity in consequence of ischemia or trauma involves the accumulation of free zinc. Rather than being a toxic metal ion, zinc is an essential trace element. Whereas intoxication by excessive exposure is rare, zinc deficiency is widespread and has a detrimental impact on growth, neuronal development, and immunity, and in severe cases its consequences are lethal. Zinc deficiency caused by malnutrition and foods with low bioavailability, aging, certain diseases, or deregulated homeostasis is a far more common risk to human health than intoxication