337 research outputs found

    Fongs nous o poc citats a Catalunya, VI

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    Fongs nous o poc citats a Catalunya. VI. En aquesta nova aportació descrivim o comentem 11 espèc ies recol·lectades a Catalunya: 1 conioforàcia i 10 agaricals, que considerem rares o encara no citades al nostre territori. Es poden destacar les següents espècies: Cortinarius sanguineus, (Wulf) Fr., Inocybe bresadolae Gill. Lactarius tabidus Fr., Lactarius lygniotus Fr., Pholiota albocrenulata (Peck) Sacc., Pholiota astragalina (Fr.) Singer i Pluteus roseipes Hoehn.New or rarely recorded fungi from Catalonia. VI. This paper includes a description and iconography of 11 species collected in Catalonia (NE Spain): 1 Coniophoraceae and 10 Agaricales, considered to be very rare or not yet recorded in this region. We highlight the following: Cortinarius sanguineus, (Wulf) Fr., Inocybe bresadolae Gill., Lacta rius tabidus Fr., Lactarius lygniotus Fr., Pholiota albocrenulata (Peck) Sacc., Pholiota astragalina (Fr.) Singer and Pluteus roseipes Hoehn.Hongos nuevos o poco citados en Cataluña. VI. En esta nueva aportación describimos o comentamos 11 especies, recolectadas en Cataluña: 1 conioforácea y 10 agaricales, que consideramos raras o todav ia no citadas en nuestro territorio. Destacamos las siguientes especies: Cortinarius sanguineus, (Wulf) Fr., Inocybe bresadolae Gill. Lactarius tabidus Fr., Lactarius lygniotus Fr., Pholiota albocrenulata (Peck) Sacc., Pholiota astragalina (Fr.) Singer i Pluteus roseipes Hoehn

    Fongs nous o poc citats a Catalunya, VI

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    Fongs nous o poc citats a Catalunya. VI. En aquesta nova aportació descrivim o comentem 11 espèc ies recol·lectades a Catalunya: 1 conioforàcia i 10 agaricals, que considerem rares o encara no citades al nostre territori. Es poden destacar les següents espècies: Cortinarius sanguineus, (Wulf) Fr., Inocybe bresadolae Gill. Lactarius tabidus Fr., Lactarius lygniotus Fr., Pholiota albocrenulata (Peck) Sacc., Pholiota astragalina (Fr.) Singer i Pluteus roseipes Hoehn.Hongos nuevos o poco citados en Cataluña. VI. En esta nueva aportación describimos o comentamos 11 especies, recolectadas en Cataluña: 1 conioforácea y 10 agaricales, que consideramos raras o todav ia no citadas en nuestro territorio. Destacamos las siguientes especies: Cortinarius sanguineus, (Wulf) Fr., Inocybe bresadolae Gill. Lactarius tabidus Fr., Lactarius lygniotus Fr., Pholiota albocrenulata (Peck) Sacc., Pholiota astragalina (Fr.) Singer i Pluteus roseipes Hoehn.New or rarely recorded fungi from Catalonia. VI. This paper includes a description and iconography of 11 species collected in Catalonia (NE Spain): 1 Coniophoraceae and 10 Agaricales, considered to be very rare or not yet recorded in this region. We highlight the following: Cortinarius sanguineus, (Wulf) Fr., Inocybe bresadolae Gill., Lacta rius tabidus Fr., Lactarius lygniotus Fr., Pholiota albocrenulata (Peck) Sacc., Pholiota astragalina (Fr.) Singer and Pluteus roseipes Hoehn

    Algunos hongos hipogeos (ascomycotina y basidiomycotina) interesantes para la micoflora española

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    Some interesting hypogeous fungi (Ascomycotina and Basidiomycotina) of the Spanish flora.— In this paper 11 species of hypogeous fungi are described and illustrated after luminic microscopy. Some of them are new to Spain, namely: Elaphomyces anthracinus Vitt., Genabea fragilis L. & Ch. Tul., Genea lespiaultii Corda, Hydnocystis piligera L. & Ch. Tul., Tuber asa L. & Ch. Tul., T. maculatum Vitt., Alpova rubescens (Vitt.) Trappe and Melanogaster macrosporus Velen.Se describen e ilustran al microscopio óptico, 11 especies de hongos hipogeos recolectados en diversos puntos de la geografía española, de los cuales Elaphomyces anthracinus Vitt., Genabea L. & Ch. Tul., Genea lespiaultii Corda, Hydnocystis piligera L. & Ch. Tul., Tuber asa L. & Ch. Tul., T. Vitt., Alpova rubescens (Vitt.) Trappe y Melanogaster macrosporus VeIen., son nuevos para España

    Algunos hongos hipogeos (ascomycotina y basidiomycotina) interesantes para la micoflora española

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    Some interesting hypogeous fungi (Ascomycotina and Basidiomycotina) of the Spanish flora. In this paper 11 species of hypogeous fungi are described and illustrated after luminic microscopy. Some of them are new to Spain, namely: Elaphomyces anthracinus Vitt., Genabea fragilis L. & Ch. Tul., Genea lespiaultii Corda, Hydnocystis piligera L. & Ch. Tul., Tuber asa L. & Ch. Tul., T. maculatum Vitt., Alpova rubescens (Vitt.) Trappe and Melanogaster macrosporus Velen.Se describen e ilustran al microscopio óptico, 11 especies de hongos hipogeos recolectados en diversos puntos de la geografía española, de los cuales Elaphomyces anthracinus Vitt., Genabea L. & Ch. Tul., Genea lespiaultii Corda, Hydnocystis piligera L. & Ch. Tul., Tuber asa L. & Ch. Tul., T. Vitt., Alpova rubescens (Vitt.) Trappe y Melanogaster macrosporus VeIen., son nuevos para España

    High expression of ecto-nucleotidases CD39 and CD73 in human endometrial tumors

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    One of the strategies used by tumors to evade immunosurveillance is the accumulation of extracellular adenosine, which has immunosupressive and tumor promoting effects. The study of the mechanisms leading to adenosine formation at the tumor interstitium are therefore of great interest in oncology. The dominant pathway generating extracellular adenosine in tumors is the dephosphorylation of ATP by ecto-nucleotidases. Two of these enzymes acting sequentially, CD39 and CD73, efficiently hydrolyze extracellular ATP to adenosine. They have been found to play a crucial role in a variety of tumors, but there were no data concerning endometrial cancer, the most frequent of the invasive tumors of the female genital tract. The aim of the present work is to study the expression of CD39 and CD73 in human endometrial cancer. We have analyzed protein and gene expression, as well as enzyme activity, in type I endometrioid adenocarcinomas and type II serous adenocarcinomas and their nonpathological endometrial counterparts. High levels of both enzymes were found in tumor samples, with significantly increased expression of CD39 in type II serous tumors, which also coincided with the higher tumor grade. Our results reinforce the involvement of the adenosinergic system in cancer, emphasizing the relevance of ecto-nucleotidases as emerging therapeutic targets in oncology

    Alguns fongs interessants del Parc Nacional d'Aigüestortes i Estany de Sant Maurici

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    El treball recull les espècies més interessants identificades recentment en l 'àrea de la Plaça dels Arbre, vora el riu Escrita, aigües avall de l 'Estany de Sl. Maurici, en una densa avetosa Són les següents: Tilachlidiopsis ' racemosa Keissl., Chrysomphalina grossula (Pers.) Norvell, Redhead et Arnmirati Clitocybula lacerata (Scop.) Métrod, Entoloma kuehnerianum Noordel., Hypsizygus ulmarius (Bull. : Fr. ) Redhead, Lactarius luridus (Pers. : Fr.) Gray, L. trivialis (Fr. : Fr.) Fr., Nidularia deformis (Willd. : Pers.) Fr. i Russula rhodopoda ZV3ra ap. Melzer et Zvara.The study of the area of la Plaça dels Arbres, near the Escrita stream, between l' Estany de St. Maurici and Espot, in a dense fir (Abies alba) woodland, has yelded some collections, selected here, and rarely or never previously recorded in Catalonia: Tilachlidiopsis racemosa Keissl., Chrysomphalina grossula (Pers.) Norvell, Redhead et Arnmirati, Clitocybula facerata (Scop.) Métrod, Entofoma kuehnerianum Noordel., Hypsizygus ulmarius (Bull.: Fr.) Redhead, Lactarius luridus (Pers. : Fr. ) Gray, L. trivialis (Fr. : Fr.) Fr., Nidularia deformis (Willd.: Pers.) Fr. and Russula rhodopoda Zvara ap. Melzer et Zvara

    Fongs nous o poc citats de Catalunya i Andorra, II

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    New or rarely recorded fungi from Catalonia and Andorra, II. Account of 8 species of Ascomycetes and 48 species of Basidiomycetes selected from our recent collections, mainly made in SW Catalonia and in the Pyrenean range. Of special taxonomic and chorologic interest are: Rutstroemia luteovirescens (Rob. ex Desm.) White, Urnula craterium (Schw.) Fr., Amanita brunneoconulus Bas et Groger, Boletus junquilleus (Quél.) Boud., Coprinus idae Uljé, Hohenbuehelia cf. angustata (Berk.) Sing., Melanoleuca nauseosa (Boekhout) Bon, Mycena maurella Robich, Oudemansiella caussei (Maire) Moser ex Clémençon, Rugosomyces fallax (Peck ex Sacc.) Bon, Russula poichilochroa Sarnari f. eliochroma Samari and R. Werneri Maire.Selección de 8 especies de Ascomicetes y 48 de Basidiomicetes, de nuestras recolecciones recientes, principalmente hechas en el S y W de Cataluña y en los Pirineos. Un interés especial, taxonómico y coro lógico es el que muestran: Rutstroemia luteovirescens (Rob. ex Desm.) White, Urnula craterium (Schw.) Fr., Amanita brunneoconulus Bas et Groger, Boletus junquilleus (Quél.) Boud., Coprinus idae Uljé, Hohenbuehelia cf. angustata (Berk.) Sing., Melanoleuca nauseosa (Boekhout) Bon, Mycena maurella Robich, Oudemansiella caussei (Maire) Moser ex Clémençon, Rugosomyces fallax (Peck ex Sacc.) Bon, Russula poichilochroa Sarnari f. eliochroma Samari y R. Werneri Maire

    Fongs nous o poc citats de Catalunya i Andorra I

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    New or rarely recorded fungi from Catalonia and Andorra, I. Contribution to the study of fungal biodiversity in NE Iberian Peninsula, with a selection of species rarely found or overlooked, collected in different habitats, including dry lands of SW Catalonia and Pyreneean localities (some of them in Andorra). Let us bring out some species, as Fimaria canina Calonge, F. Hispànica Torre et Calonge, Kotlabaea deformis (P. Karst.) Svrcek and Xylaria mornandii Bertault, among the Ascomycetes, and Camarophyllopsis hymenocephala (Hesler et Smith) Arnolds, Entoloma pseudodysthales Noord., Tabarés et Rocabruna, Glabrocyphella brunneocrystallina W.B. Cooke, Lachnella mairei (Pilàt) W.B. Cooke, Lactarius mediterraneensis LlistoselIa et Bellú, Pleuroflammula ragazziana (Bres.) Horak and Suillus Clintonianus (Peck) Kuntze, among the Basidiomycetes.Esta contribución al estudio de la biodiversidad fúngica del NE de la Península Ibérica comprende una selección de especies poco citadas o nuevas, recogidas en ambientes diversos, entre los que figuran localidades de las comarcas secas del S y SW de Cataluña y diversas localidades pirenaicas (algunas de ellas situadas en Andorra). Entre los hongos citados, podemos destacar: Fimaria canina Calonge, F. Hispànica Torre et Calonge, Kotlabaea deformis (P. Karst.) Svrcek y Xylaria mornandii Bertault, entre los Ascomicetes, y Camarophyllopsis hymenocephala (Hesler et Smith) Arnolds, Entoloma pseudodysthales Noord., Tabarés et Rocabruna, Glabrocyphella brunneocrystallina W.B. Cooke, Lachnella mairei (Pilàt) W.B. Cooke, Lactarius mediterraneensis LlistoselIa et Bellú, Pleuroflammula ragazziana (Bres .) Horak y Suillus clintonianus (Peck) Kuntze, entre los Basidiomicetes

    Fongs nous o poc citats de Catalunya i Andorra, II

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    New or rarely recorded fungi from Catalonia and Andorra, II. Account of 8 species of Ascomycetes and 48 species of Basidiomycetes selected from our recent collections, mainly made in SW Catalonia and in the Pyrenean range. Of special taxonomic and chorologic interest are: Rutstroemia luteovirescens (Rob. ex Desm.) White, Urnula craterium (Schw.) Fr., Amanita brunneoconulus Bas et Groger, Boletus junquilleus (Quél.) Boud., Coprinus idae Uljé, Hohenbuehelia cf. angustata (Berk.) Sing., Melanoleuca nauseosa (Boekhout) Bon, Mycena maurella Robich, Oudemansiella caussei (Maire) Moser ex Clémençon, Rugosomyces fallax (Peck ex Sacc.) Bon, Russula poichilochroa Sarnari f. eliochroma Samari and R. Werneri Maire.Selección de 8 especies de Ascomicetes y 48 de Basidiomicetes, de nuestras recolecciones recientes, principalmente hechas en el S y W de Cataluña y en los Pirineos. Un interés especial, taxonómico y coro lógico es el que muestran: Rutstroemia luteovirescens (Rob. ex Desm.) White, Urnula craterium (Schw.) Fr., Amanita brunneoconulus Bas et Groger, Boletus junquilleus (Quél.) Boud., Coprinus idae Uljé, Hohenbuehelia cf. angustata (Berk.) Sing., Melanoleuca nauseosa (Boekhout) Bon, Mycena maurella Robich, Oudemansiella caussei (Maire) Moser ex Clémençon, Rugosomyces fallax (Peck ex Sacc.) Bon, Russula poichilochroa Sarnari f. eliochroma Samari y R. Werneri Maire

    Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA

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    Background: Array-CGH represents a comprehensive tool to discover genomic disease alterations that could potentially be applied to body fluids. In this report, we aimed at applying array-CGH to urinary samples to characterize bladder cancer. Methods: Urinary DNA from bladder cancer patients and controls were hybridized on 44K oligonucleotide arrays. Validation analyses of identified regions and candidates included fluorescent in situ hybridization (FISH) and immunohistochemistry in an independent set of bladder tumors spotted on custom-made tissue arrays (n = 181). Results: Quality control of array-CGH provided high reproducibility in dilution experiments and when comparing reference pools. The most frequent genomic alterations (minimal recurrent regions) among bladder cancer urinary specimens included gains at 1q and 5p, and losses at 10p and 11p. Supervised hierarchical clustering identified the gain at 1q23.3-q24.1 significantly correlated to stage (p = 0.011), and grade (p = 0.002). The amplification and overexpression of Prefoldin (PFND2), a selected candidate mapping to 1q23.3-q24.1, correlated to increasing stage and tumor grade by means of custom-designed and optimized FISH (p = 0.013 and p = 0.023, respectively), and immunohistochemistry (p ≤0.0005 and p = 0.011, respectively), in an independent set of bladder tumors included in tissue arrays. Moreover, PFND2 overexpression was significantly associated with poor disease-specific survival (p ≤0.0005). PFND2 was amplified and overexpressed in bladder tumors belonging to patients providing urinary specimens where 1q23.3q24.1 amplification was detected by array-CGH. Conclusions: Genomic profiles of urinary DNA mirrowed bladder tumors. Molecular profiling of urinary DNA using array-CGH contributed to further characterize genomic alterations involved in bladder cancer progression. PFND2 was identified as a tumor stratification and clinical outcome prognostic biomarker for bladder cancer patients
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