Navigation of a manned satellite supply vehicle back to earth

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 1959.Includes bibliographical references (leaves 128-132).by James E. McCormick, John H. Axley, Forrest R. Hanvey.M.S

A Study to Determine How Total Quality Management Was Being Implemented in the Virginia Beach City Public Schools

This study will determine: 1. To what extent Virginia Beach City Public Schools are following a system of Total Quality Management?; 2. What areas of education have improved due to the use of Total Quality Management

Exploring the Experiences of School Nurses Identifying and Initiating Migraine Treatment in School-Age Children

Migraines affect about one child in twenty worldwide and have important implications for attainment and quality of life. Whereas migraines among adolescents are common, little is known about school nurses’ experience caring for this population within the school setting. This phenomenological study explored the lived experiences of school nurses in managing and treating students with migraines. Using Imogene King’s goal attainment theory as the theoretical framework, interviews with eight school nurses were conducted to understand the emotional, communicative, and practical challenges they face in providing care (Gonzalo, 2023). Key themes identified include the emotional toll of care communication barriers with students and families, limited resource access, and insufficient migraine-specific training. The findings highlight the critical need for enhanced migraine education and collaborative care strategies within schools. Although the findings are consistent with the literature, the current study is restricted by geography and does not involve any contribution from students and parents. Further studies should be done to compare different regions and school types and to study particular interventions that might help improve the student\u27s performance. Additionally, implementing collaborative programs could foster partnerships between school nurses, parents, and medical professionals to develop tailored care plans. Overall, this research contributes to an understanding of the challenges faced by school nurses and informs strategies for improving migraine management and providing support within the educational setting

Irony and the self in the lyric poetry of James Merrill.

The paper also discusses Merrill's use of form and formal poetic convention in his early lyric poetry, as well as the function of form in his two novels. His use of form suggests that it is a distancing device so that the material he is dealing with (the pain of his childhood and of love relationships) may be made more manageable.With regard to irony, the paper deals with Merrill's great theme of the evolution of the self. This great theme is manifested through two important subjects found in all of his lyric poetry: childhood and love. Merrill chooses his own life as the subject matter of most of his lyric work so that he may, through writing, resolve many of the problems his childhood created. His later lyrics suggest that he has come to terms with his past and with the fundamental ironies of existence so that he is free to live in the present. Ultimately, it is vision, and the poet as visionary, which resolves the dilemmas of his history. This vision is the stance he takes in the three book-length poems which crown his poetic career and were published in 1976, 1978, and 1980 respectively.This study was concerned with the lyric poetry of James Merrill and how irony functions in his work. The paper focuses upon the lyric poetry found in six volumes published between 1951 and 1972. It examines the concept of irony, both superficial (rhetorical) and profound, and discusses how Merrill uses both types in his work

Control Share Statutes

This Article gives an overview of the different types of anti-takeover legislation, paying particular attention to control share statutes. The Article follows the development of control share statutes and the surrounding litigation in Missouri, Hawaii, Ohio and Indiana. The Article also points to questions that remain unanswered by the CTS decision, and operational problems with current control share statutes

Influencia de la ubicación de las aberturas en la eficiencia de la ventilación en viviendas

Building ventilation implies managing the “clean” air and extracting the contaminated air through the walls, distributing and circulating the incoming air and preventing the contamination of the indoor air. The Spanish Technical Building Code, in his section HS3 – IAQ, usually set up minimum ventilation flow rates according to its typology, surface, possible contamination sources or the number of occupants, without thinking over the path of the air from the inlet to the exhaust point. For that reason, even if such standards are met within the spaces of the home, there may still be areas in the interior that suffer an excess or deficit of ventilation. The present study aims to overcome the purely quantitative performance of DBHS3, to control qualitatively the air renewal throughout the living space; this allows even to reduce the volumetric flow rate with the consequent energetic saving.El proceso de ventilación incluye impulsar aire “limpio” y extraer el viciado a través de los cerramientos, distribuir y hacer circular el aire entrante y prevenir la contaminación interior. El Código Técnico de la Edificación, en su Sección HS3 – Calidad del Aire Interior, establece unos caudales mínimos de ventilación generalistas a cumplir en viviendas en función de su tipología, superficie, posibles fuentes contaminantes y número de ocupantes, sin considerar la trayectoria del aire desde su admisión hasta su extracción. Por dicha razón ocurre el hecho que, aunque se cumpla la Normativa en cuanto al recinto a ventilar, pueden existir zonas en el interior que presenten exceso o déficit de ventilación. El estudio que se presenta tiene como objetivo superar el cumplimiento meramente cuantitativo del DB-HS3, para controlar cualitativamente la renovación del aire en todo el espacio habitable, lo que permite incluso reducir el caudal con el consiguiente ahorro energético

Efficient CO2-Reducing Activity of NAD-Dependent Formate Dehydrogenase from Thiobacillus sp KNK65MA for Formate Production from CO2 Gas

NAD-dependent formate dehydrogenase (FDH) from Candida boidinii (CbFDH) has been widely used in various CO2 reduction systems but its practical applications are often impeded due to low CO2-reducing activity. In this study, we demonstrated superior CO2-reducing properties of FDH from Thiobacillus sp. KNK65MA (TsFDH) for production of formate from CO2 gas. To discover more efficient CO2-reducing FDHs than a reference enzyme e. CbFDH, five FDHs were selected with biochemical properties and then, their CO2-reducing activities were evaluated. All FDHs including CbFDH showed better CO2-reducing activities at acidic pHs than at neutral pHs and four FDHs were more active than CbFDH in the CO2 reduction reaction. In particular, the FDH from Thiobacillus sp. KNK65IVIA (TsFDH) exhibited the highest CO2-reducing activity and had a dramatic preference for the reduction reaction, i.e., a 84.2-fold higher ratio of CO2 reduction to formate oxidation in catalytic efficiency (k(cat)/K-B) compared to CbFDH. Formate was produced from CO2 gas using TsFDH and CbFDH, and TsFDH showed a 5.8-fold higher formate production rate than CbFDH. A sequence and structural comparison showed that FDHs with relatively high CO2-reducing activities had elongated N- and C-terminal loops. The experimental results demonstrate that TsFDH can be an alternative to CbFDH as a biocatalyst in CO2 reduction systemsope

Actividades lúdicas y su aporte en el estado físico y emocional del adulto mayor

El presente trabajo de intervención logra tocar temas de alta relevancia y que han sido desapercibidos ante la sociedad, como es, la desatención ante problemas físicos y psicológicos en personas de la tercera edad, para esto se tomó en cuenta las actividades lúdicas y su aporte en el estado físico-emocional. Las destrezas que podrían simbolizar un avance entre personas de la tercera edad suelen consistir en estimular diferentes factores como la creatividad y destrezas motoras según sus capacidades. Para cubrir estos campos se planteó como objetivo una recopilación bibliográfica que pretende contextualizar las necesidades de cada persona para aportar en el mejoramiento de la calidad de vida. Y su posterior análisis de la importancia que genera en el adulto mayor las actividades lúdicas para su bienestar. Las actividades con mayor beneficio se relacionan con el juego y la recreación saludable en el logro del bienestar activo y participativo, recalcando que pueden influir en el mejoramiento del estilo de vida en personas mayores, explorando el área física como fuerza muscular y movilidad, también el área emocional como disminución del estrés, bienestar psicológico y el estado de ánimo. Lo anteriormente citado sirvió de insumo para el diseño y la implementación de los talleres de desarrollo físico y emocional, dando una buena aceptación de los adultos mayores. Como conclusión la adaptación e implementación de los diferentes talleres, logro estimular su flexibilidad cerebral, concentración, memoria, atención, gestión emocional y movimiento corporal. Así también la recomendación está en implementar actividades lúdicas para el fortalecimiento cognitivo.The present intervention work manages to touch on issues of high relevance and which have been overlooked by society, such as the inattention to physical and psychological problems in elderly people, for this we took into account the playful activities and their contribution to the physical-emotional state. Skills that could symbolize advancement among older people often involve stimulating different factors such as creativity and motor skills according to their abilities. In order to cover these fields, the aim was to compile a bibliographic collection that aims to contextualize the needs of each person in order to contribute to the improvement of the quality of life. And their subsequent analysis of the importance that playful activities generate in older adults for their well-being. The most beneficial activities are related to play and healthy recreation to achieve active and participatory well-being, stressing that they can influence the improvement of lifestyle in older people, exploring the physical area such as muscle strength and mobility, as well as the emotional area such as stress reduction, psychological well-being and mood. The aforementioned information served as input for the design and implementation of the physical and emotional development workshops, which were well accepted by older adults. As a conclusion, the adaptation and implementation of the different workshops, I managed to stimulate their brain flexibility, concentration, memory, attention, emotional management and body movement. Thus, the recommendation is to implement recreational activities for cognitive strengthening

Quantitative Analysis of Dynamic Protein Interactions during Transcription Reveals a Role for Casein Kinase II in Polymerase-associated Factor (PAF) Complex Phosphorylation and Regulation of Histone H2B Monoubiquitylation

Using affinity purification MS approaches, we have identified a novel role for casein kinase II (CKII) in the modification of the polymerase associated factor complex (PAF-C). Our data indicate that the facilitates chromatin transcription complex (FACT) interacts with CKII and may facilitate PAF complex phosphorylation. Posttranslational modification analysis of affinity-isolated PAF-C shows extensive CKII phosphorylation of all five subunits of PAF-C, although CKII subunits were not detected as interacting partners. Consistent with this, recombinant CKII or FACT-associated CKII isolated from cells can phosphorylate PAF-C in vitro, whereas no intrinsic kinase activity was detected in PAF-C samples. Significantly, PAF-C purifications combined with stable isotope labeling in cells (SILAC) quantitation for PAF-C phosphorylation from wild-type and CKII temperature-sensitive strains (cka1Δ cka2–8) showed that PAF-C phosphorylation at consensus CKII sites is significantly reduced in cka1Δ cka2–8 strains. Consistent with a role of CKII in FACT and PAF-C function, we show that decreased CKII function in vivo results in decreased levels of histone H2B lysine 123 monoubiquitylation, a modification dependent on FACT and PAF-C. Taken together, our results define a coordinated role of CKII and FACT in the regulation of RNA polymerase II transcription through chromatin via phosphorylation of PAF-C

SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements

Selenoproteins are a diverse group of proteins usually misidentified and misannotated in sequence databases. The presence of an in-frame UGA (stop) codon in the coding sequence of selenoprotein genes precludes their identification and correct annotation. The in-frame UGA codons are recoded to cotranslationally incorporate selenocysteine, a rare selenium-containing amino acid. The development of ad hoc experimental and, more recently, computational approaches have allowed the efficient identification and characterization of the selenoproteomes of a growing number of species. Today, dozens of selenoprotein families have been described and more are being discovered in recently sequenced species, but the correct genomic annotation is not available for the majority of these genes. SelenoDB is a long-term project that aims to provide, through the collaborative effort of experimental and computational researchers, automatic and manually curated annotations of selenoprotein genes, proteins and SECIS elements. Version 1.0 of the database includes an initial set of eukaryotic genomic annotations, with special emphasis on the human selenoproteome, for immediate inspection by selenium researchers or incorporation into more general databases. SelenoDB is freely available at http://www.selenodb.org