2,420 research outputs found
Understanding the experiences of Latino/a non-academic employees at the University of Missouri
Dissertation supervisor: Dr. Casandra Harper.Includes vita.Using a narrative methodology of inquiry framed by an intersectionality theoretical framework, the purpose of this qualitative research study was to use testimonios to explore and describe the experiences of Latino/a non-academic employees (i.e., staff who work in service/maintenance jobs) at MU. This research study ultimately attempted to generate knowledge about the professional, educational, and personal journeys of traditionally marginalized workers. The central question of this study was: what are the life histories of Latino/a nonacademic employees at MU and do issues of identity, power, and hierarchy emerge within those testimonios? One secondary question is: What opportunities do Latino/a non-academic employees have to develop their professional and educational careers? Using an intersectionality framework of analysis, this study presented the lived experiences and personal narratives of Jose and Maria within the context of the study research questions. This empirical qualitative study described the importance of knowing and understanding the experiences of Latino/a non-academic employees at MU.Includes bibliographical references (pages 149-165)
INNOVACIÓN EN LOS SISTEMAS DE PAGOS: EL CASO DEL MERCADO DE TRANSFERENCIAS DE CRÉDITO EN EL PERU
El presente trabajo es una primera aproximación al análisis de los factores que explican el menor desarrollo del mercado de transferencias de crédito en el Perú, a pesar de las ventajas que tiene respecto al uso del efectivo y del cheque. Siguiendo la literatura sobre el tema de innovación, el análisis parte de la concepción de que los sistemas de pago son una industria de red y en ese contexto se busca identificar incentivos y limitantes que tienen los agentes para el desarrollo del mercado. Se concluye que entre los factores limitantes se tiene a: • La estructura de comisiones a nivel del servicio de compensación y de los clientes del sistema financiero. • El incentivo de los bancos por invertir en sus propias redes, en lugar de hacerlo en la red común. • La falta de cultura financiera. • Presencia de mecanismos de pago de obligaciones que limitan el desarrollo de los sistemas de pagos. De esta forma, existe una tarea de difusión y de coordinación para que el mercado de transferencias de crédito se desarrolle, beneficiándose los agentes económicos por el menor riesgo y mayor eficiencia para el pago de sus transacciones.
Regional geology subprogram: Geological interpretation of ERTS imagery of the occidental region of Bolivia
The author has identified the following significant results. Using ERTS-1 imagery, it is possible to delimit great lithological units, folds, lineaments, faults, and in lesser degree unconformities. In the morphological aspect, the images show clearly the relief necessary for geological interpretation. The ERTS-1 images are important for the preparation of the geological and tectonic map of Bolivia, on a 1:1 million scale, if conventional methods of work are used as a base
A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence
Although an effective interferon antagonist in human and avian cells, the novel H7N9 influenza virus NS1 protein is defective at inhibiting CPSF30. An I106M substitution in H7N9 NS1 can restore CPSF30 binding together with the ability to block host gene expression. Furthermore, a recombinant virus expressing H7N9 NS1-I106M replicates to higher titers in vivo, and is subtly more virulent, than parental. Natural polymorphisms in H7N9 NS1 that enhance CPSF30 binding may be cause for concern
Out of time: theorising family in social work practice
This paper draws on a British Academy (BA) funded study exploring social workers' conceptions of family using a vignette and focus groups. The policy context is discussed and the data from the BA study are then compared and contrasted with families' accounts of their own situations using the data from a separate qualitative study about child protection social work. The paper discusses the themes emerging and argues for a renewed focus on theorizing family in children's social work and the implications for practice
Questioning assent: how are children's views included as families make decisions about clinical trials?
BACKGROUND: Assent is used to take children's wishes into account when they are invited into clinical trials, but the concept has attracted considerable criticism. We investigated children's accounts of decision-making with the aim of informing practice in supporting children when invited to join a clinical trial. METHODS: We audio-recorded qualitative, semi-structured interviews with 22 children aged 8-16 years about being invited to take part in a clinical trial. Most children were interviewed with their parents. Analysis of the transcribed interviews examined the content of participants' accounts thematically, whilst also drawing on principles of discourse analysis, which examines how individuals use talk to achieve certain effects or social practices. RESULTS: It was not possible to separate children's knowledge of the clinical trial, or their decision-making processes from that of their parents, with parents taking a substantial mediating role in producing their children's decisions. Decision-making gradually unfolded across time and events and was interwoven within the family context, rather than happening in one moment or in the clinical setting. Whilst children valued their parents' role, a case study of child-parent disagreement indicated how children can struggle to be heard. CONCLUSIONS: Decisions happen within a process of family dynamics, in contrast to ideas of assent that isolate it from this context. Parents have a substantial role in children's decisions, and thus how families come to provide consent. Reflecting this we argue that assent practices need to focus on supporting parents to support their children in learning and deliberating about trials. However, this needs to be accompanied by practitioners being alert to the possibility of divergence in child and parent views and enabling children's perspectives to be heard
The role of heart rate on the associations between body composition and heart rate variability in children with overweight/obesity : the ActiveBrains project
Background: Heart rate variability (HRV) is negatively associated with body mass index and adiposity in several populations. However, less information is available about this association in children with overweight and obesity, especially severe/morbid obesity, taking into consideration the dependence of HRV on heart rate (HR).
Objectives: (1) to examine associations between body composition measures and HRV, (2) to study differences in HRV between children with overweight and severe/morbid obesity; and (3) to test whether relationships and differences tested in objectives 1 and 2, respectively are explained by the dependency of HRV on HR.
Methods: A total of 107 children with overweight/obesity (58% boys, 10.03 +/- 1.13 years) participated in this study. Body composition measures were evaluated by Dual-energy X-ray absorptiometry (DXA). HRV parameters were measured with Polar RS800CXR (R).
Results: Body composition measures were negatively associated with HRV indicators of parasympathetic activity (beta values ranging from -0.207 to -0.307, all p 0.05).
Conclusion: All associations between adiposity/obesity and HRV could be explained by HR, suggesting a key confounding role of HR in HRV studies in children with weight disturbances
Influencia de grelina y leptina sobre alteraciones psiquiátricas en sujetos con obesidad
La obesidad (índice de masa corporal [IMC] > 30 kg/m2) se define como el exceso en la proporción del tejido adiposo; consecuencia de un ingreso calórico superior al gasto energético del individuo. Es considerada un problema inflamatorio, sistémico, crónico y recurrente que causa diversas complicaciones. Esta enfermedad se ha relacionado con diversos problemas metabólicos y fisiológicos ampliamente estudiados; además de psicopatológicos.La obesidad es un problema de salud pública en diversos países, principalmente en Norteamérica. Se ha observado que sujetos que presentan obesidad manifiestan numerosas alteraciones psiquiátricas, entre ellas: depresión, ansiedad y trastorno por atracón. Por ello, diversos estudios han llegado a la conclusión de que las hormonas gastrointestinales fungen un papel crucial en el establecimiento de conductas, siendo la orexigénica grelina y la anorexigénica leptina 2 de las hormonas con mayor participación activa. Dicha intervención se debe a que ambas hormonas presentan receptores en sistema nervioso central, primordialmente en áreas del sistema límbico, regulador crucial de conductas hedónicas. Por lo tanto, en la presente revisión bibliográfica describiremos el papel de la grelina y la leptina sobre la expresión de conductas psicopatológicas comunes en sujetos que padecen obesidad
Inflammatory biomarkers and brain health indicators in children with overweight and obesity: The ActiveBrains project
INTRODUCTION: Chronic inflammation plays an important role on the pathogenesis of several cardiovascular and metabolic diseases, as well as on brain function and behaviour. The aim of the present study was to examine the associations between inflammatory biomarkers and a wide range of brain health indicators (i.e., academic performance, executive function, behavioural and emotional functioning, and brain volume) in children with overweight/obesity.
METHODS: A total of 107 children (10.0 ± 1.1 years, 41% girls) from the ActiveBrains project were included in the analysis. Five inflammatory biomarkers were analysed in plasma: white blood cell (WBC) count, interleukin-6 (IL-6), interleukin-1beta, tumor necrosis factor-alpha (TNF-alpha), and C-reactive protein (CRP). Academic performance was assessed by Woodcock-Munoz Tests of Achievement. Executive function was assessed through the Design Fluency Test for cognitive flexibility, the Stroop test for cognitive inhibition, and the Delayed Non-Match-to-Sample task for working memory. Behavioural and emotional functioning was evaluated through the Behavior Assessment System for Children (BASC) questionnaire. Total and regional brain volume was assessed by magnetic resonance imaging.
RESULTS: IL-6 was inversely associated with adaptive skills (beta = -0.228; p = 0.030), while TNF-alpha was related to mathematics (beta = -0.198; p = 0.034). In addition, CRP was positively associated with externalizing (beta = 0.246; p = 0.046) and internalizing problems (beta = 0.234; p = 0.039), as well as the behavioural symptoms index (beta = 0.236; p = 0.047). However, these significant associations disappeared after multiple comparisons correction. Inflammatory biomarkers were not associated with executive function and total brain volumes. Regarding regional brain analyses, WBC was positively associated with gray matter volume in the left middle temporal gyrus (beta = 0.387; p < 0.001, k = 44), and CRP was positively associated with gray matter volume in the right superior temporal gyrus (beta = 0.439; p < 0.001, k = 29). Additionally, when adjusting by total brain volume, CRP was positively associated with gray matter volume in the right supplementary motor cortex (beta = 0.453; p < 0.001, k = 51). Moreover, both, IL-6 (beta = 0.366; p < 0.001, k = 81) and TNF-alpha (beta = 0.368; p < 0.001, k = 62) were positively associated with white matter volume around the right inferior frontal gyrus pars opercularis, while CRP was inversely associated with white matter volume around the left superior frontal gyrus (beta = -0.482; p < 0.001, k = 82). After adjusting by total brain volume, CRP was also inversely associated with white matter volume in 3 additional clusters (beta ranging from -0.473 to -0.404; p < 0.001, k = 87).
CONCLUSIONS: Inflammation was slightly associated with brain health (i.e., academic performance, behavioural and emotional functioning and regional brain volume) in children with overweight or obesity. Further larger longitudinal and interventional studies are warranted to elucidate the short-term and long-term effect of systemic low-grade inflammation on children's brain health
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