Awareness of HPV and HPV vaccination in undergraduate students in the North West region of Turkey: Near future outlook

Introduction: Cervical cancer is the second most common cancer affecting women in the world. Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. The aim of this study was to evaluate the awareness about HPV, risk perception, cervical cancer, and HPV vaccines. Methodology: The sample of this descriptive cross-sectional study consisted of 396 undergraduate university students from Turkey. Sociodemographic characteristics, reproductive health, knowledge about HPV, and HPV vaccination were questioned. Results: The percentage of university students with an active sexual life was 10.6%. The knowledge level of families about HPV, and HPV vaccination were not adequate. The awareness of the fact that HPV was a cause of cervical cancer in women and penile cancer in men tended to increase with the increase in the educational level of parents. Those who knew about HPV vaccines were predominantly females. Conclusions: The results of this study demonstrated that more active education is needed to decrease HPV infections among undergraduate students. Increasing awareness of HPV makes it easier to develop positive behaviors in fighting against it. In order to increase the contribution of young people to educational activities for the community, information about HPV and HPV vaccines should first be included in training programs at universities. To support the development of effective and high-quality public health interventions, young people should be educated so that obstacles to HPV vaccination in various cultural groups can be eliminated. Our findings suggest that awareness about HPV, cervical cancer, and HPV vaccines should be increased

The Relationship Between Lifestyle, Health Promotion Lifestyle Profile II And High Blood Pressure In University Students

BACKGROUND: Identifying and controlling systemic arterial blood pressure is important in young people, and it is possible to reduce the frequency of systemic arterial hypertension by improving the lifestyle. AIM: The aim of the study is to assess the relationship between healthy lifestyle behaviors and systemic blood pressure in university students. MATERIALS: The study sample consisted of 200 university students from a state university in Edirne. Lifestyles and habits were evaluated with Health Promotion Lifestyle Profile II. Students’ blood pressure was measured from both arms twice. RESULTS: The mean HPLP-II score of those who frequently feel good was significantly higher than those who rarely feel good. The mean score of those who frequently wake up between 06:00-09:00 in the morning was statistically significantly higher than those who wake up outside these hours. Those who perform social or artistic activities during their leisure times had a mean scale score higher than those who don’t perform. Although there wasn’t a statistically significant difference according to smoking status, the mean score of non-smokers was higher than smokers. The mean scale scores were higher in frequent salt users than non-frequent users; participants with low saturated fatty acid intake had higher scores than those with high intake, and rare fast food consumers had higher scores than frequent consumers. The statistically significant difference between blood pressure values of females and males was due to higher blood pressure in male students. Those working in a part-time job had higher blood pressure values than those who weren’t working. Among the students whose body mass indexes could be evaluated, there were differences in blood pressure values. CONCLUSION: It has been observed in our study that health-related responsibilities and lifestyle behaviours increase with better leisure time activities, improved eating habits and a positive outlook on life. Turning youngs’ tendencies towards healthy lifestyle behaviours to habits can make them healthier, more collective and more productive regarding physical, social and psychological well-being

Isolated hypoglossal nerve palsy in a child

We report an 11-year-old boy who had isolated hypoglossal nerve palsy one week after symptoms and signs of urticarial lesions. Neuroradiological examinations and other investigations for etiology of hypoglossal nerve palsy and urticaria were normal. We suggest that all patients with hypoglossal palsy must be carefully evaluated for atypical findings and etiologies

Investigation of NF-B1 and NF-BIA Gene Polymorphism in Non-Small Cell Lung Cancer

Lung cancer is a complex, multifactorial disease which is the leading cause of cancer death in both men and women. NF-B is a transcription factor which is known to affect the expression of more than 150 genes related to inflammation, lymphocyte activation, cell proliferation, differentiation, and apoptosis, as well as contributing to cell apoptosis and survival. However, NF-BIA (I B ) is the inhibitor of the transcription factor. The -94ins/delATTG polymorphism of the NF-B1 gene promoter region which causes a functional effect and NF-BIA 3 UTR A → G polymorphism has been shown to be related to various inflammatory diseases and cancer. Ninety-five NSCLC patients and 99 healthy controls were included in study. The NF-B1 -94ins/delATTG and NF-BIA 3 UTR A → G polymorphism have been studied by using PCR-RFLP method. It was found that the NF-B1 -94ins/delATTG DD genotype and D allele frequencies were higher in patients than healthy controls and the presence of the DD genotype has a 3.5-fold increased risk of the disease (P: 0.014). This study is the first to investigate the NF-B1 -94ins/delATTG and NF-BIA 3 UTR A → G polymorphism together in the Turkish population. According to the results, the NF-B1 -94ins/del ATTG promoter polymorphism may have a role in lung carcinogenesis and prognosis

Clinical, electrophysiological and neuropsychological findings of twenty-two children with mesial temporal sclerosis

Twenty-two patients, followed with the diagnosis of epilepsy between the ages of 8.5 and 19 years who were found to have mesial temporal sclerosis (MTS) on brain magnetic resonance imaging (MRI) were evaluated according to their clinical, electrophysiological and neuropsychological characteristics, and assessed for the significance of neuropsychological tests on lateralization. In both MTS groups, a remarkable number of patients had their intial seizure before one year of age (45.5% in the right MTS group, and 36.4% in the left MTS group). Half of the patients were seizure-free for a period of two months-9.5 years (average 3.9 years). The duration between the febrile seizure and first non-febrile seizure was 6.2 years. Eleven patients had MTS on the left temporal lobe. Interictal EEG was normal in five (22.5%) patients; 10 (45.5%) had temporal spike on the corresponding side with MTS. Six (27.3%) patients had paroxysmal activity and voltage asymmetry on cortical areas other than temporal region. The Wechsler Memory Scale (WMS), Visual Reproduction Subtest and Auditory Verbal Learning Test (AVLT) Delayed Recall and Retrieval Subtest performances were poor in the right MTS group

Bilateral femoral neck fractures due to transient osteoporosis of pregnancy: a case report

We describe a case of bilateral femoral neck fractures secondary to transient osteoporosis of pregnancy, which were diagnosed after delivery due to the desire to avoid ionising radiation. These fractures were presumed to be secondary to transient osteoporosis of pregnancy and were treated successfully with internal fixation despite delayed presentation. We discuss the role of MRI in the evaluation of hip pain in pregnancy

Evaluation of 36 patients from Turkey with neuronal ceroid lipofuscinosis: clinical, neurophysiological, neuroradiological and histopathologic studies

Neuronal ceroid lipofuscinosis (NCL) is one of the most common progressive neurodegenerative diseases seen in childhood. NCL is inherited as autosomal recessive trait, and is characterized by the accumulation of 'ceroid lipofuscin' in neuronal and extraneuronal cells. Clinical features include seizures, ataxia, myoclonus, loss of vision, and mental and motor deterioration. Although the disease is widely seen across the world, there seems to be an information gap in Asian countries. To date, no comprehensive and detailed studies on NCL have been carried out in Turkey. However, one could predict that the disease is rather frequent in Turkey due to high rates of consanguineous marriages. Thirty-six Turkish patients were evaluated in this study. Sixteen (44.5%) patients were girls, and 20 (55.5%) were boys. Parents were consanguineous in 25 families (80%). In five families (14%), the disease was seen in two sibs. The diagnosis was based on clinical evaluation, and neurophysiological, neuroradiologic, enzymatic, and histopathological studies. Electron microscopic study was the main diagnostic laboratory test. Three patients were classified as infantile NCL, 11 were late infantile NCL, 5 were juvenile type NCL and 17 patients were Turkish variant NCL. In juvenile type, major initial symptom was visual impairment, whereas in all other types seizures were predominantly the first symptom at the onset of the disease. The initial symptoms of Turkish variant NCL were similar to those of late infantile type. Similar age at clinical symptoms and the presence of visual symptoms were common features of Turkish variant and juvenile NCL. Compared to late infantile NCL, Turkish variant, showed a more severe course regarding seizures. Electroencephalogram (EEG) showed abnormal features predominantly in Turkish variant, and were remarkable for occipital spikes. In patients with Turkish variant magnetic resonance imaging of the brain showed brainstem involvement, especially pons, in all patients except one; cerebral and cerebellar atrophy were seen with a slower course compared to late infantile NCL. Clinical picture of NCL in advanced stages of the disease was similar regardless of the subtype

AMİNOMETİL)POLİSTİRENE TAKILI SCHIFF BAZI VE O'NUN Ni(II) KOMPLEKSİNİN SENTEZİ, KARAKTERİZASYONU VE b- GALAKTOSİDAZ ENZİMİNİN İMMOBİLİZASYON ÖZELLİKLERİNİN İNCELENMESİ

Bu çalışmada, 2-fenilindol-3-karboksaldehit (2-PIn-Ald) ile (aminometil)polistirenin (APS) kondenzasyonu sonucunda bir Schiff bazı (APS– 2PIn-Sch), ve bunun Ni(II) kompleksi (APS-2PIn-Sch-Ni) sentezlenmiştir. (APS–2PIn-Sch) ve (APS-2PIn-Sch-Ni) polimerleri elementel analiz ve spektral analizlerle karakterize edilmiştir. Ayrıca (APS–2PIn-Sch) ve (APS-2PIn-Sch- Ni)'in, Termal Gravimetrik Analiz (TGA) ile kararlılıkları, Taramalı Elektron Mikroskopi (SEM) ile morfolojik yapıları karakterize edilmiştir. Ek olarak, bu maddelerin elementel analiz sonuçlarına göre yapıları öngörülerek, ağırlıkca ortalama molekül kütleleri önerilmiştir (Mw). Sonrasında ise, (APS), (APS– 2PIn-Sch) ve (APS-2PIn-Sch-Ni) komplekslerine kovalent bağlama yöntemi ile β-Galaktosidaz immobilize edilmiştir. Serbest ve immobilize β-Galaktosidaz üzerine sıcaklık, pH, tekrar kullanım, depolama kararlılığı gibi parametrelerin etkisi araştırılmıştır. Serbest enzim ve kovalent bağlanma yöntemi ile (APS), (APS–2PIn-Sch) ve (APS-2PIn-Sch-Ni)'e immobilize edilen enzimler için Km ve Vmak değerleri sırasıyla 0,343mM 0,0259 mM.dak-1, 0,681 mM 0,0716 mM.dak-1, 0,0363 mM 0,0185 mM.dak-1, 0,380 mM 0,0718 mM.dak-1 olarak hesaplanmıştır. (APS-2PIn-Sch-Ni)'in depolama kararlılığı diğer polimerlere oranla daha yüksek çıkmıştır.Polymer-bound Schiff-base ligand (APS-2PIn-Sch) was prepared from (aminomethyl)polystyrene (APS) bound 2-phenlyindole-3-carboxaldehyde (2PIn-Ald) and its Ni(II)complex (APS-2PIn-Sch-Ni) was also synthesized. The (APS-2PIn-Sch) and its Ni(II)complex were characterized on the basis of elemental analyses and spectral analyses studies. (APS-2PIn-Sch) and (APS- 2PIn-Sch-Ni) were further characterized thermally, employing thermogravimetry (TGA) and morphologically employing scanning electron microscopy (SEM). In addition, main units have been suggested with elemental analysis for these substances, and than the weight average molecular weight (Mw) has been suggested. After that, β-Galactosidase were immobilized onto (APS), (APS–2PIn-Sch) and (APS-2PIn-Sch-Ni) complex with using the covalent binding. The influence of temperature, pH and reusability, storage capacity on the free and immobilized β-Galactosidase were investigated. Kinetic parameters were calculated as 0.343mM/0.0259 mM.min−1, 0.681 mM/0.0716 mM.min−1, 0.0363 mM/0.0185 mM.min−1 and 0.380 mM/0.0718 mM.min−1, for Km/Vmax respectively; free, (APS), (APS–2PIn-Sch) and (APS–2PIn-Sch–Ni) bound enzymes. Storage capacity of (APS–2PIn-Sch–Ni) was found higher than other polymers