Cocaine use in Europe - a multi-centre study: patterns of use in different groups

AIM The study investigates patterns of cocaine powder and crack cocaine use of different groups in nine European cities. DESIGN, SETTING, PARTICIPANTS Multi-centre cross-sectional study conducted in Barcelona, Budapest, Dublin, Hamburg, London, Paris, Rome, Vienna, and Zurich. Data were collected by structured face-to-face interviews. The sample comprises 1,855 cocaine users out of three subgroups: 632 cocaine users in addiction treatment, mainly maintenance treatment; 615 socially marginalized cocaine users not in treatment, and 608 socially integrated cocaine users not in treatment. MEASUREMENTS Use of cocaine powder, crack cocaine and other substances in the last 30 days, routes of administration, and lifetime use of cocaine powder and crack cocaine. FINDINGS The marginalized group showed the highest intensity of cocaine use, the highest intensity of heroin use and of multiple substance use. 95% of the integrated group snorted cocaine powder, while in the two other groups, injecting was quite prevalent, but with huge differences between the cities. 96% of all participants had used at least one other substance in addition to cocaine in the last 30 days. CONCLUSIONS The use of cocaine powder and crack cocaine varies widely between different groups and between cities. Nonetheless, multiple substance use is the predominating pattern of cocaine use, and the different routes of administration have to be taken into account

Classifying finite monomial linear groups of prime degree in characteristic zero

Let [Formula: see text] be a prime and let [Formula: see text] be the complex field. We explicitly classify the finite solvable irreducible monomial subgroups of [Formula: see text] up to conjugacy. That is, we give a complete and irredundant list of [Formula: see text]-conjugacy class representatives as generating sets of monomial matrices. Copious structural information about non-solvable finite irreducible monomial subgroups of [Formula: see text] is also proved, enabling a classification of all such groups bar one family. We explain the obstacles in that exceptional case. For [Formula: see text], we classify all finite irreducible subgroups of [Formula: see text]. Our classifications are available publicly in MAGMA. </jats:p

Projections from the lateral vestibular nucleus to the spinal cord in the mouse

The present study investigated the projections from the lateral vestibular nucleus (LVe) to the spinal cord using retrograde and anterograde tracers. Retrogradely labeled neurons were found after fluoro-gold injections into both the cervical and lumbar cord, with a smaller number of labeled neurons seen after lumbar cord injections. Labeled neurons in the LVe were found in clusters at caudal levels of the nucleus, and a small gap separated these clusters from labeled neurons in the spinal vestibular nucleus (SpVe). In the anterograde study, BDA-labeled fiber tracts were found in both the ventral and ventrolateral funiculi on the ipsilateral side. These fibers terminated in laminae 6–9. Some fibers were continuous with boutons in contact with motor neurons in both the medial and lateral motor neuron columns. In the lumbar and sacral segments, some collaterals from the ipsilateral vestibulospinal tracts were found on the contralateral side, and these fibers mainly terminated in laminae 6–8. The present study reveals for the first time the fiber terminations of the lateral vestibular nucleus in the mouse spinal cord and therefore enhances future functional studies of the vestibulospinal system

Relationship Between Alexithymia and Aggression in a Sample of Men with Substance Dependence

Objective:The aim of this study Was to evaluate the relationship between alexithymia and aggression among men with substance dependence. In addition, we wanted to control the effect of variables such as depression and anxiety on this relationship