New features of the thermal Casimir force at small separations

The difference of the thermal Casimir forces at different temperatures between real metals is shown to increase with a decrease of the separation distance. This opens new opportunities for the demonstration of the thermal dependence of the Casimir force. Both configurations of two parallel plates and a sphere above a plate are considered. Different approaches to the theoretical description of the thermal Casimir force are shown to lead to different measurable predictions.Comment: 5 pages, 3 figures, to appear in Phys. Rev. Let

Casmir-Lifshitz Forces and Entropy

It is shown that the violation of the positiveness of the entropy due to the Casimir-Lifshitz interaction claimed in several papers is an artifact related to an improper interpretation of the "Casimir entropy", which actually is a difference of two positive terms. It is explained that at definite condition this "Casimir entropy" must be negative. A direct derivation of the low temperature behavior of the surface entropy of a metallic surface in conditions of the anomalous skin effect is given and singular temperature dependency of this quantity is discussed. In conclusion a hydrodynamic example of the entropy of a liquid film is considered. It occurs that the entropy of a film of finite thickness and a liquid half-space behave differently at T tends to 0.Comment: 4 page

Den allvarliga lärarbristen i Sverige - hur kunde detta hända och vad kan vi göra?

I denna artikel redovisas troliga orsaker till den omfattande lärarbristen i Sverige och möjligheter att lösa den på längre sikt. Data är baserat på en omfattande litteraturöversikt och en webbundersökning. Den teoretiska förankringen återfinns i tre styrningsteorier och dess konsekvenser för det studerade området. Resultatet visar att lärarbristen kan spåras minst 50 år tillbaka i tiden och att orsakerna är många och komplexa, exempelvis många olika reformer, försämrade villkor, låg status för yrket och New Public Management som styrningsfilosofi. Möjligheterna att lösa problemen på lång sikt är flera: högre löner, bättre arbetsvillkor, stärkt professionsidentitet, högre status samt flexibla vägar att studera till lärare.

Intrahepatic Transcriptomics Differentiate Advanced Fibrosis and Clinical Outcomes in Adults With Fontan Circulation.

BACKGROUND: The molecular mechanisms underlying Fontan-associated liver disease (FALD) remain largely unknown. OBJECTIVES: This study aimed to assess intrahepatic transcriptomic differences among patients with FALD according to the degree of liver fibrosis and clinical outcomes. METHODS: This retrospective cohort study included adults with the Fontan circulation. Baseline clinical, laboratory, imaging, and hemodynamic data as well as a composite clinical outcome (CCO) were extracted from medical records. Patients were classified into early or advanced fibrosis. RNA was isolated from formalin-fixed paraffin-embedded liver biopsy samples; RNA libraries were constructed with the use of an rRNA depletion method and sequenced on an Illumina Novaseq 6000. Differential gene expression and gene ontology analyses were performed with the use of DESeq2 and Metascape. RESULTS: A total of 106 patients (48% male, median age 31 years [IQR: 11.3 years]) were included. Those with advanced fibrosis had higher B-type natriuretic peptide levels and Fontan, mean pulmonary artery, and capillary wedge pressures. The CCO was present in 23 patients (22%) and was not predicted by advanced liver fibrosis, right ventricular morphology, presence of aortopulmonary collaterals, or Fontan pressures on multivariable analysis. Samples with advanced fibrosis had 228 upregulated genes compared with early fibrosis. Samples with the CCO had 894 upregulated genes compared with those without the CCO. A total of 136 upregulated genes were identified in both comparisons and were enriched in cellular response to cytokine stimulus or oxidative stress, VEGFA-VEGFR2 signaling pathway, TGF-β signaling pathway, and vasculature development. CONCLUSIONS: Patients with FALD and advanced fibrosis or the CCO exhibited upregulated genes related to inflammation, congestion, and angiogenesis

A procedure to correct proxy-reported weight in the National Health Interview Survey, 1976–2002

<p>Abstract</p> <p>Background</p> <p>Data from the National Health Interview Survey (NHIS) show a larger-than-expected increase in mean BMI between 1996 and 1997. Proxy-reports of height and weight were discontinued as part of the 1997 NHIS redesign, suggesting that the sharp increase between 1996 and 1997 may be artifactual.</p> <p>Methods</p> <p>We merged NHIS data from 1976–2002 into a single database consisting of approximately 1.7 million adults aged 18 and over. The analysis consisted of two parts: First, we estimated the magnitude of BMI differences by reporting status (i.e., self-reported versus proxy-reported height and weight). Second, we developed a procedure to correct biases in BMI introduced by reporting status.</p> <p>Results</p> <p>Our analyses confirmed that proxy-reports of weight tended to be biased downward, with the degree of bias varying by race, sex, and other characteristics. We developed a correction procedure to minimize BMI underestimation associated with proxy-reporting, substantially reducing the larger-than-expected increase found in NHIS data between 1996 and 1997.</p> <p>Conclusion</p> <p>It is imperative that researchers who use reported estimates of height and weight think carefully about flaws in their data and how existing correction procedures might fail to account for them. The development of this particular correction procedure represents an important step toward improving the quality of BMI estimates in a widely used source of epidemiologic data.</p

The Accumulation of Organic Carbon in Mineral Soils by Afforestation of Abandoned Farmland

The afforestation of abandoned farmland significantly influences soil organic carbon (OC). However, the dynamics between OC inputs after afforestation and the original OC are not well understood. To learn more about soil OC dynamics after afforestation of farmland, we measured the soil OC content in paired forest and farmland plots in Shaanxi Province, China. The forest plots had been established on farmland 18, 24, 48, 100, and 200 yr previously. The natural 13C abundance of soil organic matter was also analyzed to distinguish between crop- and forest-derived C in the afforested soils. We observed a nonlinear accumulation of total OC in the 0–80 cm depth of the mineral soil across time. Total soil OC accumulated more rapidly under forest stands aged 18 to 48 yr than under forest stands aged 100 or 200 yrs. The rate of OC accumulation was also greater in the 0–10 cm depth than in the 10–80 cm depth. Forest-derived OC in afforested soils also accumulated nonlinearly across time, with the greatest increase in the 0–20 cm depth. Forest-derived OC in afforest soils accounted for 52–86% of the total OC in the 0–10 cm depth, 36–61% of the total OC in the 10–20 cm depth, and 11–50% of the total OC in the 20–80 cm depth. Crop-derived OC concentrations in the 0–20 cm depth decreased slightly after afforestation, but there was no change in crop-derived OC concentrations in the 20–80 cm depth. The results of our study support the claim that afforestation of farmland can sequester atmospheric CO2 by increasing soil OC stocks. Changes in the OC stocks of mineral soils after afforestation appear to be influenced mainly by the input of forest-derived C rather than by the loss of original OC

The first samples from Almahata Sitta showing contacts between ureilitic and chondritic lithologies: implications for the structure and composition of asteroid 2008 TC 3

Almahata Sitta (AhS), an anomalous polymict ureilite, is the first meteorite observed to originate from a spectrally classified asteroid (2008 TC3). However, correlating properties of the meteorite with those of the asteroid is not straightforward because the AhS stones are diverse types. Of those studied prior to this work, 70–80% are ureilites (achondrites) and 20–30% are various types of chondrites. Asteroid 2008 TC3 was a heterogeneous breccia that disintegrated in the atmosphere, with its clasts landing on Earth as individual stones and most of its mass lost. We describe AhS 91A and AhS 671, which are the first AhS stones to show contacts between ureilitic and chondritic materials and provide direct information about the structure and composition of asteroid 2008 TC3. AhS 91A and AhS 671 are friable breccias, consisting of a C1 lithology that encloses rounded to angular clasts (<10 μm to 3 mm) of olivine, pyroxenes, plagioclase, graphite, and metal‐sulfide, as well as chondrules (~130–600 μm) and chondrule fragments. The C1 material consists of fine‐grained phyllosilicates (serpentine and saponite) and amorphous material, magnetite, breunnerite, dolomite, fayalitic olivine (Fo 28‐42), an unidentified Ca‐rich silicate phase, Fe,Ni sulfides, and minor Ca‐phosphate and ilmenite. It has similarities to CI1 but shows evidence of heterogeneous thermal metamorphism. Its bulk oxygen isotope composition (δ18O = 13.53‰, δ17O = 8.93‰) is unlike that of any known chondrite, but similar to compositions of several CC‐like clasts in typical polymict ureilites. Its Cr isotope composition is unlike that of any known meteorite. The enclosed clasts and chondrules do not belong to the C1 lithology. The olivine (Fo 75‐88), pyroxenes (pigeonite of Wo ~10 and orthopyroxene of Wo ~4.6), plagioclase, graphite, and some metal‐sulfide are ureilitic, based on mineral compositions, textures, and oxygen isotope compositions, and represent at least six distinct ureilitic lithologies. The chondrules are probably derived from type 3 OC and/or CC, based on mineral and oxygen isotope compositions. Some of the metal‐sulfide clasts are derived from EC. AhS 91A and AhS 671 are plausible representatives of the bulk of the asteroid that was lost. Reflectance spectra of AhS 91A are dark (reflectance ~0.04–0.05) and relatively featureless in VNIR, and have an ~2.7 μm absorption band due to OH− in phyllosilicates. Spectral modeling, using mixtures of laboratory VNIR reflectance spectra of AhS stones to fit the F‐type spectrum of the asteroid, suggests that 2008 TC3 consisted mainly of ureilitic and AhS 91A‐like materials, with as much as 40–70% of the latter, and <10% of OC, EC, and other meteorite types. The bulk density of AhS 91A (2.35 ± 0.05 g cm−3) is lower than bulk densities of other AhS stones, and closer to estimates for the asteroid (~1.7–2.2 g cm−3). Its porosity (36%) is near the low end of estimates for the asteroid (33–50%), suggesting significant macroporosity. The textures of AhS 91A and AhS 671 (finely comminuted clasts of disparate materials intimately mixed) support formation of 2008 TC3 in a regolith environment. AhS 91A and AhS 671 could represent a volume of regolith formed when a CC‐like body impacted into already well‐gardened ureilitic + impactor‐derived debris. AhS 91A bulk samples do not show a solar wind component, so they represent subsurface layers. AhS 91A has a lower cosmic ray exposure (CRE) age (~5–9 Ma) than previously studied AhS stones (11–22 Ma). The spread in CRE ages argues for irradiation in a regolith environment. AhS 91A and AhS 671 show that ureilitic asteroids could have detectable ~2.7 μm absorption bands

Does sea level influence mid-ocean ridge magmatism on Milankovitch timescales?

Magma production at mid-ocean ridges is driven by seafloor spreading and decompression melting of the upper mantle. In the special case of Iceland, mantle melting may have been amplified by ice sheet retreat during the last deglaciation, yielding anomalously high rates of subaerial volcanism. For the remainder of the global mid-ocean ridge system, the ocean may play an analogous role, with lowering of sea level during glacial maxima producing greater magma flux to ridge crests. Here we show that the mantle decompression rate associated with changes in sea level is a substantial fraction of that from plate spreading. Modeled peaks in magma flux occur after sea level drops rapidly, including the Marine Isotope Stage (MIS) 5/4 and 3/2 transitions. The minimum in simulated flux occurs during the mid-Holocene, due to the rapid sea level rise at the MIS 2/1 boundary. The model results are highly sensitive to melt migration rate; rates of ~1 m/yr produce small signals, while those >5 m/yr yield substantial anomalies. In the latter case, sea level-driven magma flux varies by 15–100% relative to the long-term average, with the largest effect occurring at slow-spreading ridges. We suggest that sedimentary time series of hydrothermal particle flux, oceanic Os isotopic ratio, and oceanic radiocarbon may serve as proxies for magma-flux variations at mid-ocean ridges. Although well-dated records are rare, preliminary data from the Pacific and Atlantic suggest hydrothermal metal flux was elevated during MIS 2 and 4, broadly consistent with our modeling results