Potentials of cellulosic wastes in media formulation

Potential use of cellulosic wastes as carbon and energy sources in selective media formulations was investigated. Two agar media, Czapek-Dox and Sabouraud’s agar, were modified by substituting their carbon sources with cellulose, sawdust and sugarcane pulps. Then, two fungi; Aspergillus niger ANL301 and Penicillium chrysogenum PCL501, newly isolated from wood-wastes, were transferred to the unmodified and modified media and their growth was monitored for 120 h. Growth of the organisms on modified media containing sawdust and sugarcane pulp compared favorably with that obtained for the unmodified equivalents. Modified Czapek-Dox agar containing 2% (w/v) sawdust (Wood agar) and sugarcane pulps (Cane agar) gave 78.9 – 93.3% of the maximum growth obtained on Sabouraud’s agar. The modified Sabouraud’s agar containing sawdust (Wood-Pep agar) and sugarcane pulps (Cane-Pep agar) yielded 84.4 – 100% of the maximum growth on Sabouraud’s agar. Cellulose-containing media gave a lower level of growth (60.0 – 66.7%) of that obtained for the unmodified media

Corporate Social Responsibility as a Determinant of Sustainability of Small Medium Enterprises (SMEs)

In the pursuit of profit maximization as a major objective of business organizations, several firms forfeit their social and economic responsibility whilst focusing on activities that are deemed to solely profit the firm, without taking into cognizance the effect of their operations on the society in which they operate. Business analysts have however, realized the determinant role of social responsibility in corporate performance, such that firms that are able to imbibe corporate social responsibility in their core business operations may be able to take advantage of the social reputation gained across their several stakeholders. Small and medium enterprises operating in highly competitive markets are also advised to leverage on this reputation gained from being socially responsible, if they seek ways to remain relevant in the same markets dominated by multinational corporations. Adapting a case study approach, this study highlights the advantages (such as employee and customer loyalty) gained by House of Tara, a small business operating in the beauty and make-up industry in Nigeria, resulting from the firm‘s commitment to advancing the society in which it operates through several social responsibility activities. It is observed that although competing with major makeup brands such as MAC, Maybelline, Dior, Mary Kay and others, House of Tara has been able to not only thrive, but gain a sizeable market in the Nigerian makeup industry, because several consumers purchase their products not solely because of the quality or price of their product, but because they perceive themselves as buying into the firm‘s CSR vision. This study therefore recommends that small and medium enterprises that may lack adequate resources (manpower, technology, capital) needed to successfully compete with multinationals, can harness the potentials in the reputation and loyalty gained from adequate investment in corporate social responsibility

Effect of mastery learning approach on senior school students' academic performance and retention in Circle Geometry

This study examined the effect of mastery learning on senior secondary school students’ achievement and retention in circle geometry. The study was conducted in Ilorin, Kwara state, Nigeria. It adopted a quasi-experimental, non-randomized, pre-test, post-test control group design. A sample of 172 senior school II students was drawn from four co-educational schools using multi-stage sampling technique. Instrument for data collection was Circle Geometry Achievement Test (CGAT) which was validated by experts and reliability index of 0.82 was obtained using test-retest method. The result showed that senior school students’ achievement in Geometry improved significantly when taught circle geometry using mastery learning approach. There was no gender difference found as well as no difference in the achievement of low, medium and high scoring students when taught with mastery learning approach. There was also a significance difference in the post test mean score and retention score of students taught circle geometry using mastery learning approach. It was recommended among others that trainings should be given to mathematics teachers on how to effectively use mastery learning approach in mathematics classroom if better performance is desired

EVALUATION OF OPEN POLLINATED MAIZE VARIETIES FOR RESISTANCE/TOLERANCE TO Striga hermonthica Del. Benth AT MOKWA SOUTHERN GUINEA SAVANNAH OF NIGERIA

Three trials were conducted on the College of Agriculture experimental field which was highly anduniformly infested by Striga at Mokwa (latitude 09o 18'N and longitude 05o 04'E) in the SouthernGuinea Savanna agro- ecological zone of Nigeria during 2004, 2005 and 2006 wet seasons. The studywas conducted to evaluate fifteen maize genotypes consisting of eleven improved, open- pollinatedStriga tolerant varieties, a susceptible 8338-1 and tolerant hybrids 9022-13, an improved recommendedopen pollinated variety and a local selection (Mokwa Dzurugi) for their reaction to Striga hermonthica.The treatments were laid out in a randomized complete block design and replicated fourtimes. Among the varieties tested, TZL Comp.1Syn Y-1F2, Cam, 1 STR – 1 and hybrid 9022-13 consistentlyresulted in significantly lower Striga emergence and crop syndrome reaction to Striga parasitismcompared to all the other varieties including STR genotypes in 2004 and 2005 and of very lowvalues of the parameters in 2006. The varieties also gave higher grain yield comparable to most oftolerant varieties evaluated. Under Striga infestation, maize grain yields of var. TZL Comp. 1 Syn Y-1F2 were 2.94, 3.04 and 2.93 times than those of the recommended TZB- STR (1015kg/ha, 989kg/haand 993kg/ha) in 2004, 2005 and 2006, respectively. The corresponding values for the other promisingvariety, Cam- 1STR-1 were 2.93, 3.05 and 2.89 times higher than TZB STR in 2004, 2005 and 2006respectively. The local selection, Mokwa Dzurugi also exhibited good performance with respect toStriga and maize parameters and could therefore be used in the breeding programme for Striga resistance

Estimation of the Thermal Diffusivity of Beans Using a Simple Apparatus

A simple apparatus for the determination of the thermal diffusivity of black-eyed beans samples, using the transient heat conduction method is presented. This apparatus is a stainless steel cylindrical tube, containing the sample, placed into a constant temperature water bath. The variation of the temperature at the center of the tube with time is recorded. The thermal diffusivities were determined from the temperature-time relationship data of the sample, and the dimensions of the equipment.  The estimated thermal diffusivity values of the samples varied between 4.70 x 10-8 to 6.94 x 10-8 and 5.26 x 10-8 to 7.68 x 10-8 when the temperature in the water bath was 50oC and 60oC, respectively.  Also, the thermal diffusivity was higher when the water bath temperature was 60oC rather than 50oC for the sample range of particle sizes studied. As black-eyed beans are a staple food in many parts of West African, they are grown, harvested, and stored. The thermal diffusivity information is useful in determining the behaviour of this Argo-product when stored. Keywords: Beans, Thermal Diffusivity, Transient Heat Conduction Method

Hepatitis b, c and hiv serological markers in children with sickle cell anaemia in a tertiary hospital, Gusau, North-Western Nigeria

Sickle Cell Anaemia patients are considered to be among the high-risk groups for hepatitis B and C viral infections. These viruses and HIV share common routes of transmission and similar risk factors and their infections coexist. Objective: This study was aimed at determining the seroprevalence of hepatitis B, C and HIV viral markers of infections in children with SCA. Methodology: A cross sectional Hospital based study conducted on 89 confirmed SCA Children aged 6 months – 13 years in steady state attending Haematology Clinic in a Specialist Hospital Gusau from July 2017 to March 2018. Approval for the study was obtained from the Research and Ethics Committee of the Hospital. The age, gender, history of blood transfusion, traditional scarification, uvulectomy, circumcision and immunization of the subjects were recorded. Serological test was carried out to determine the prevalence of hepatitis B, C and HIV using the viral markers and HIV 1& 2 rapid test kits. Results: Eighty-nine subjects were recruited with 46(51.7%) males and 43(48.3%) females. The mean age was 5.06 ±3.4 years. The seroprevalence of HBsAg, HBsAb, HBcAb, HBeAg, HBeAb, AntiHCV and HIV 1& 2 were 3(3.4%), 3(3.4%), 5(5.7%), 1(1.1%), 6(6.9%) and 0% respectively. No co-infection among the studied subjects. There is no significant difference in the age or gender distribution and seroprevalence of the viruses among SCA children. p = > 0.05 Conclusion: Hepatitis C infection is found to be high as opposed to Hepatitis B which is lower among SCA Children in this community

Elucidating the Antimycobacterial Mechanism of Action of Decoquinate Derivative RMB041 Using Metabolomics

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), still remains one of the leading causes of death from a single infectious agent worldwide. The high prevalence of this disease is mostly ascribed to the rapid development of drug resistance to the current anti-TB drugs, exacerbated by lack of patient adherence due to drug toxicity. The aforementioned highlights the urgent need for new anti-TB compounds with different antimycobacterial mechanisms of action to those currently being used. An N-alkyl quinolone; decoquinate derivative RMB041, has recently shown promising antimicrobial activity against Mtb, while also exhibiting low cytotoxicity and excellent pharmacokinetic characteristics. Its exact mechanism of action, however, is still unknown. Considering this, we used GCxGC-TOFMS and well described metabolomic approaches to analyze and compare the metabolic alterations of Mtb treated with decoquinate derivative RMB041 by comparison to non-treated Mtb controls. The most significantly altered pathways in Mtb treated with this drug include fatty acid metabolism, amino acid metabolism, glycerol metabolism, and the urea cycle. These changes support previous findings suggesting this drug acts primarily on the cell wall and secondarily on the DNA metabolism of Mtb. Additionally, we identified metabolic changes suggesting inhibition of protein synthesis and a state of dormancy

ONLINE NEWSPAPER READERSHIP IN THE NORTH EASTERN NIGERIA

ABSTRACT The study investigate