A Survey of Extragalactic Faraday Rotation at High Galactic Latitude: The Vertical Magnetic Field of the Milky Way towards the Galactic Poles

We present a study of the vertical magnetic field of the Milky Way towards the Galactic poles, determined from observations of Faraday rotation toward more than 1000 polarized extragalactic radio sources at Galactic latitudes |b| > 77 degs, using the Westerbork Radio Synthesis Telescope and the Australia Telescope Compact Array. We find median rotation measures (RMs) of 0.0 +/- 0.5 rad/m^2 and +6.3 +/- 0.7 rad/m^2 toward the north and south Galactic poles, respectively, demonstrating that there is no coherent vertical magnetic field in the Milky Way at the Sun's position. If this is a global property of the Milky Way's magnetism, then the lack of symmetry across the disk rules out pure dipole or quadrupole geometries for the Galactic magnetic field. The angular fluctuations in RM seen in our data show no preferred scale within the range ~ 0.1 to 25 degs. The observed standard deviation in RM of ~ 9 rad/m^2 then implies an upper limit of ~1microGauss on the strength of the random magnetic field in the warm ionized medium at high Galactic latitudes.Comment: 38 pages, 7 figures, 3 tables Accepted for publication in ApJ, Electronic versions of Tables 1 and 2 are available via email from the first autho

New Constraints on the Galactic Halo Magnetic Field using Rotation Measures of Extragalactic Sources Towards the Outer Galaxy

We present a study of the Milky Way disk and halo magnetic field, determined from observations of Faraday rotation measure (RM) towards 641 polarized extragalactic radio sources in the Galactic longitude range 100-117 degs, within 30 degs of the Galactic plane. For |b| < 15 degs, we observe a symmetric RM distribution about the Galactic plane. This is consistent with a disk field in the Perseus arm of even parity across the Galactic mid-plane. In the range 15<|b|<30 degs, we find median rotation measures of -15+/-4 rad/m^2 and -62+/-5 rad/m^2 in the northern and southern Galactic hemispheres, respectively. If the RM distribution is a signature of the large-scale field parallel to the Galactic plane, this suggests that the halo magnetic field toward the outer Galaxy does not reverse direction across the mid-plane. The variation of RM as a function of Galactic latitude in this longitude range is such that RMs become more negative at larger |b|. This is consistent with an azimuthal magnetic field of strength 2 microGauss (7 microGauss) at a height 0.8-2 kpc above (below) the Galactic plane between the local and the Perseus spiral arm. We propose that the Milky Way could possess spiral-like halo magnetic fields similar to those observed in M51.Comment: 23 pages, 9 figures, 2 tables. Accepted for publication in ApJ. Electronic version of Table 1 is available via email from the first autho

Two randomised and placebo-controlled studies of an oral prostacyclin analogue (Iloprost) in severe leg ischaemia [The Oral Iloprost in severe Leg Ischaemia Study Group]

Two separate studies are described using the same prostacyclin analogue in a similar group of patients. Objectives: to assess the tolerability and efficacy of two dose regimens of oral Iloprost compared with placebo in the treatment of patients with ischaemic ulcers, gangrene or rest pain due to severe arterial disease over a period of 4 weeks (Study A) and one year (Study B). Design: multicentre, placebo controlled, double-blind, randomized prospective studies. Subjects & Methods: 178 (study A) and 624 (study B) patients with trophic skin lesions (ulcers or gangrene) or ischaemic rest pain due to severe arterial disease. To confirm severe arterial disease patients were required to have a systolic ankle Doppler pressure of 70 mmHg or less or a toe systolic Doppler pressure of 50 mmHg or less in one leg.In both studies patients were randomly allocated to three treatment groups: placebo, low dose Iloprost (50\u2013100 g twice a day) or high dose (150\u2013200 g twice a day) In Study A the main outcome measures were tolerability of different doses of Iloprost and death, major amputation, healing of trophic lesions and relief of rest pain at the end of the follow up, which was 5 months after the end of the treatment. In Study B the primary end point was time to major amputation and stroke or death up to 12 months. Secondary pre-defined end points included the combined end point of patients alive without amputation, no trophic skin changes, no rest pain and not on regular analgesics. Results: the proportion of patients who completed the 4-week treatment period in Study A at the intended dose was 58%, 43%, 45% respectively in the placebo, low dose and high dose Iloprost groups. In an intention to treat analysis the proportion of patients who survived without major amputation, ulcers or gangrene and had no rest pain was 11% in the placebo group, 19% in the low dose iloprost group and 28% in the high dose Iloprost group. The pooled Iloprost groups showed a statistically significantly better result than the placebo group (p=0.04), as did the high dose Iloprost group compared to the placebo (p=0.014). In Study B there was no treatment benefit in terms of a primary end point of amputation and death. However the secondary combined end point of patients who survived without a major amputation, ulcers or gangrene and had no rest pain, nor a need for regular analgesia was favourable for Iloprost, with 18% of patients in the placebo group reaching this optimal secondary end point, compared to 23% in the low dose Iloprost group and 26% in the higher dose Iloprost group (p<0.05). Conclusions: oral Iloprost administered for a year showed no clear benefit in patients with advanced severe leg ischaemia (PAOD III and IV). The results obtained with 4 weeks\u2019 treatment in Study A and in previous trials of intravenous Iloprost could not be reproduce

Ecosystem services and hydroelectricity in Central America: modelling service flows with fuzzy logic and expert knowledge

Because ecosystem services are generally not produced and used in the same place, their assessment should consider the flows of services from ecosystems to users. These flows depend on the characteristics and spatial distribution of ecosystems and users, the spatial relationships between them, and the presence of filters or barriers between ecosystems and users. The objective of this paper is to map the ecosystem services provided to the Costa Rican and Nicaraguan hydroelectric sectors, which are crucial sectors for national sustainable development and depend directly on hydrological ecosystem services. The paper presents an approach for modelling the flows of multiple services from diverse ecosystems to diverse users through different kinds of filters in a landscape. The approach uses expert knowledge and fuzzy numbers to handle uncertainties. The analyses for Costa Rica and Nicaragua show how the approach helps identify priority areas for the conservation and restoration of forests for the services they provide to the hydroelectric sector. As such, it is a useful tool for defining spatially targeted policies for the conservation of ecosystem services and for involving the users of ecosystem services in ecosystem management. (Résumé d'auteur