9 research outputs found

    Search for massive resonances in dijet systems containing jets tagged as W or Z boson decays in pp collisions at √s=8 TeV

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    The Influence of Cerebrovascular Pathology on Cluster Analysis of Neuropsychological Scores in Patients With Mild Cognitive Impairment

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    Abstract Objectives The diagnostic entity of mild cognitive impairment (MCI) is heterogeneous, highlighting the need for data-driven classification approaches to identify patient subgroups. However, these approaches can be strongly determined by sample characteristics and selected measures. Here, we applied a cluster analysis to an MCI patient database from a neuropsychology clinic to determine whether the inclusion of patients with MCI with vascular pathology would result in a different classification of subgroups. Methods Participants diagnosed with MCI (n = 166), vascular cognitive impairment—no dementia (n = 26), and a group of older adults with subjective cognitive concerns but no objective impairment (n = 144) were assessed using a full neuropsychological battery and other clinical measures. Cognitive measures were analyzed using a hierarchical cluster analysis and then a k-means approach, with resulting clusters compared on a range of demographic and clinical variables. Results We found a 4-factor solution: a cognitively intact cluster, a globally impaired cluster, an amnestic/visuospatial impairment cluster, and a mild, mixed-domain cluster. Interestingly, group differences in self-reported multilingualism emerged in the derived clusters that were not observed when comparing diagnostic groups. Conclusions Our results were generally consistent with previous studies using cluster analysis in MCI. Including patients with primarily cerebrovascular disease resulted in subtle differences in the derived clusters and revealed new insights into shared cognitive profiles of patients beyond diagnostic categories. These profiles should be further explored to develop individualized assessment and treatment approaches. </jats:sec

    Search for top-squark pairs decaying into Higgs or Z bosons in pp collisions at s=8 TeV

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    AbstractA search for supersymmetry through the direct pair production of top squarks, with Higgs (H) or Z bosons in the decay chain, is performed using a data sample of proton–proton collisions at s=8 TeV collected in 2012 with the CMS detector at the LHC. The sample corresponds to an integrated luminosity of 19.5 fb−1. The search is performed using a selection of events containing leptons and bottom-quark jets. No evidence for a significant excess of events over the standard model background prediction is observed. The results are interpreted in the context of simplified supersymmetric models with pair production of a heavier top-squark mass eigenstate t˜2 decaying to a lighter top-squark mass eigenstate t˜1 via either t˜2→Ht˜1 or t˜2→Zt˜1, followed in both cases by t˜1→tχ˜10, where χ˜10 is an undetected, stable, lightest supersymmetric particle. The interpretation is performed in the region where the mass difference between the t˜1 and χ˜10 states is approximately equal to the top-quark mass (mt˜1−mχ˜10≃mt), which is not probed by searches for direct t˜1 squark pair production. The analysis excludes top squarks with masses mt˜2<575 GeV and mt˜1<400 GeV at a 95% confidence level

    Constraints on the Higgs boson width from off-shell production and decay to Z-boson pairs

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    AbstractConstraints are presented on the total width of the recently discovered Higgs boson, ΓH, using its relative on-shell and off-shell production and decay rates to a pair of Z bosons, where one Z boson decays to an electron or muon pair, and the other to an electron, muon, or neutrino pair. The analysis is based on the data collected by the CMS experiment at the LHC in 2011 and 2012, corresponding to integrated luminosities of 5.1 fb−1 at a center-of-mass energy s=7 TeV and 19.7 fb−1 at s=8 TeV. A simultaneous maximum likelihood fit to the measured kinematic distributions near the resonance peak and above the Z-boson pair production threshold leads to an upper limit on the Higgs boson width of ΓH<22 MeV at a 95% confidence level, which is 5.4 times the expected value in the standard model at the measured mass of mH=125.6 GeV

    Search for exotic decays of a Higgs boson into undetectable particles and one or more photons

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    AbstractA search is presented for exotic decays of a Higgs boson into undetectable particles and one or two isolated photons in pp collisions at a center-of-mass energy of 8 TeV. The data correspond to an integrated luminosity of up to 19.4 fb−1 collected with the CMS detector at the LHC. Higgs bosons produced in gluon–gluon fusion and in association with a Z boson are investigated, using models in which the Higgs boson decays into a gravitino and a neutralino or a pair of neutralinos, followed by the decay of the neutralino to a gravitino and a photon. The selected events are consistent with the background-only hypothesis, and limits are placed on the product of cross sections and branching fractions. Assuming a standard model Higgs boson production cross section, a 95% confidence level upper limit is set on the branching fraction of a 125 GeV Higgs boson decaying into undetectable particles and one or two isolated photons as a function of the neutralino mass. For this class of models and neutralino masses from 1 to 120 GeV an upper limit in the range of 7 to 13% is obtained. Further results are given as a function of the neutralino lifetime, and also for a range of Higgs boson masses

    Intrinsic connectivity reveals functionally distinct cortico-hippocampal networks in the human brain

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