4,577 research outputs found
The Impact of Employer-Provided Health Insurance on Dynamic Employment Transitions
We estimate the impact of employer-provided health insurance (EPHI) on the job mobility of males over time using a dynamic empirical model that accounts for unobserved heterogeneity. Previous studies of job-lock reach different conclusions about possible distortions in labor mobility stemming from an employment-based health insurance system: a few authors find no evidence of job-lock, while most find reductions in the mobility of insured workers of between 20 and 40%. WE use data from the National Longitudinal Survey of Youth which describes the health insurance an individual holds, as well as whether he is offered insurance by his employer. This additional information allows us to model the latent individual characteristics that are correlated with the offer of EPHI, the acceptance of EPHI, and employment transitions. Our results provide an estimate of job-lock unbiased through correlation with positive job characteristics and individual specific turnover propensity. We find no evidence of job-lock among married males, and produce small estimates of job-lock among unmarried males of between 10 and 15%.
Flow field computations for blunt bodies in planetary environments
Numerical analysis on flow distribution around hypersonic blunt body in planetary atmospher
Shape-dependence of particle rotation in isotropic turbulence
We consider the rotation of neutrally buoyant axisymmetric particles
suspended in isotropic turbulence. Using laboratory experiments as well as
numerical and analytical calculations, we explore how particle rotation depends
upon particle shape. We find that shape strongly affects orientational
trajectories, but that it has negligible effect on the variance of the particle
angular velocity. Previous work has shown that shape significantly affects the
variance of the tumbling rate of axisymmetric particles. It follows that shape
affects the spinning rate in a way that is, on average, complementary to the
shape-dependence of the tumbling rate. We confirm this relationship using
direct numerical simulations, showing how tumbling rate and spinning rate
variances show complementary trends for rod-shaped and disk-shaped particles.
We also consider a random but non-turbulent flow. This allows us to explore
which of the features observed for rotation in turbulent flow are due to the
effects of particle alignment in vortex tubes
Is Foreign Direct Investment Good for Growth? Evidence from Sectoral Analysis of China and Vietnam
We estimate the impact of FDI on growth using sectoral data for FDI inflows to China and Vietnam. Previous empirical studies, using either cross-country growth regressions or firm-level micro-econometric analysis, fail to reach a consensus. Our paper is the first to use sectoral FDI inflow data to evaluate the sector-specific impact of FDI on growth. Our results show that, for the two developing-transition economies we examine, FDI has a statistically-significant positive effect on economic growth operating directly and through its interaction with labor. Intriguingly, we find the effects seem to be very different across economic sectors, with almost all the beneficial impact limited to industrial sector. Other sectors appear to gain very little growth benefit from sector-specific FDI.Foreign direct investment, growth, China, Vietnam
Neuregulin 1-Beta cytoprotective role in AML 12 mouse hepatocytes exposed to pentachlorophenol.
Neuregulins are a family of growth factor domain proteins that are structurally related to the epidermal growth factor. Accumulating evidence has shown that neuregulins have cyto- and neuroprotective properties in various cell types. In particular, the neuregulin-1 Beta (NRG1-Beta) isoform is well documented for its antiinflammatory properties in rat brain after acute stroke episodes. Pentachlorophenol (PCP) is an organochlorine compound that has been widely used as a biocide in several industrial, agricultural, and domestic applications. Previous investigations from our laboratory have demonstrated that PCP exerts both cytotoxic and mitogenic effects in human liver carcinoma (HepG2) cells, primary catfish hepatocytes and AML 12 mouse hepatocytes. We have also shown that in HepG2 cells, PCP has the ability to induce stress genes that may play a role in the molecular events leading to toxicity and tumorigenesis. In the present study, we hypothesize that NRG1-Beta will exert its cytoprotective effects in PCP-treated AML 12 mouse hepatocytes by its ability to suppress the toxic effects of PCP. To test this hypothesis, we performed the MTT-cell respiration assay to assess cell viability, and Western-blot analysis to assess stress-related proteins as a consequence of PCP exposure. Data obtained from 48 h-viability studies demonstrated a biphasic response; showing a dose-dependent increase in cell viability within the range of 0 to 3.87 microg/mL, and a gradual decrease within the concentration range of 7.75 to 31.0 microg/mL in concomitant treatments of NRG1-Beta+PCP and PCP. Cell viability percentages indicated that NRG1-Beta+PCPtreated cells were not significantly impaired, while PCP-treated cells were appreciably affected; suggesting that NRG1-Beta has the ability to suppress the toxic effects of PCP. Western Blot analysis demonstrated the potential of PCP to induce oxidative stress and inflammatory response (c-fos), growth arrest and DNA damage (GADD153), proteotoxic effects (HSP70), cell cycle arrest as consequence of DNA damage (p53), mitogenic response (cyclin- D1), and apoptosis (caspase-3). NRG1-Beta exposure attenuated stress-related protein expression in PCP-treated AML 12 mouse hepatocytes. Here we provide clear evidence that NRG1-Beta exerts cytoprotective effects in AML 12 mouse hepatocytes exposed to PCP
Context-Bounded Analysis For Concurrent Programs With Dynamic Creation of Threads
Context-bounded analysis has been shown to be both efficient and effective at
finding bugs in concurrent programs. According to its original definition,
context-bounded analysis explores all behaviors of a concurrent program up to
some fixed number of context switches between threads. This definition is
inadequate for programs that create threads dynamically because bounding the
number of context switches in a computation also bounds the number of threads
involved in the computation. In this paper, we propose a more general
definition of context-bounded analysis useful for programs with dynamic thread
creation. The idea is to bound the number of context switches for each thread
instead of bounding the number of switches of all threads. We consider several
variants based on this new definition, and we establish decidability and
complexity results for the analysis induced by them
The effect of photobleaching on bee (Hymenoptera: Apoidea) setae color and its implications for studying aging and behavior
Historically, bee age has been estimated using measurements of wing wear and integument color change. These measurements have been useful in studies of foraging ecology and plant-pollinator interactions. Wing wear is speculated to be affected by the behaviors associated with foraging, nesting, and mating activities. Setal color change may be an additional parameter used to measure bee age if it is affected by sun exposure during these same activities. The objectives of this study were to experimentally assess the effect of direct sun exposure on setal color, unicellular hair-like processes of the integument, and determine whether wing wear and integument photobleaching are correlated. To quantify photobleaching of setae, we measured changes in hue of lab-reared Bombus huntii Greene (Apidae) exposed to natural sunlight. We found that sun exposure was a significant variable in determining setal bleaching. To assess the relationship between wing wear and setal photobleaching, we scored wing wear and measured setal hue of B. huntii, Melecta pacifica fulvida Cresson (Apidae), and Osmia integra Cresson (Megachilidae) from museum specimens. Wing wear and setal hue values were positively correlated for all three species; however, the strength of the relationship varies across bee species as indicated by correlation coefficient estimates. Our results suggest that setal color change is affected by sun exposure, and is likely an accurate estimate of bee age. We suggest that future investigations of bee aging consider a suite of morphometric characteristics due to differences in natural history and sociobiology that may be confounded by the use of a single characteristic
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Pro-tobacco marketing and anti-tobacco campaigns aimed at vulnerable populations: A review of the literature.
INTRODUCTION:We reviewed research literature on pro-tobacco marketing and anti-tobacco campaigns targeting eight vulnerable populations to determine key findings and research gaps. Results can inform tobacco policy and control efforts and the design of public education campaigns for these groups. METHODS:Five journal databases in medicine, communication, and science, were used to identify 8875 peer-reviewed, original articles in English, published in the period 2004-2018. There were 144 articles that met inclusion criteria on pro-tobacco marketing or anti-tobacco campaigns aimed at eight US groups: women of reproductive age, racial/ethnic minority groups (African American, Hispanic/Latino, Asian/Pacific Islander and American Indian/Alaska Native), Lesbian/Gay/Bisexual/Transgender (LGBT) populations, groups with low socioeconomic status, rural/inner city residents, military/veterans, and people with mental health or medical co-morbidities. We summarized the number of articles for each population, type of tobacco, and pro-tobacco or anti-tobacco focus. Narrative summaries were organized by population and by pro-tobacco or anti-tobacco focus, with key strategies and gaps by group. RESULTS:There were more studies on pro-tobacco marketing rather than anti-tobacco campaigns, and on cigarettes rather than other tobacco products. Major gaps included studies on Asian Americans, American Indian/Alaska Natives, pregnant women, LGBT populations, and those with mental health or medical co-morbidities. Gaps related to tobacco products were found for hookah, snus, and pipe/roll-your-own tobacco in the pro-tobacco studies, and for all products except cigarettes in anti-tobacco studies. Common tobacco industry methods used were tailoring of product and package design and messages that were used to reach and appeal to different sociodemographic groups. Studies varied by research design making it difficult to compare results. CONCLUSIONS:We found major research gaps for specific groups and tobacco products. Public education campaigns need a stronger foundation in empirical studies focused on these populations. Research and practice would benefit from studies that permit comparisons across studies
Dynamic models for longitudinal butterfly data
There has been recent interest in devising stochastic models for seasonal insects, which
respond rapidly to climate change. Fitted to count data, these models are used to construct
indices of abundance, which guide conservation and management. We build upon Dennis et
al. (2014, under review) to produce dynamic models, which provide succinct descriptions of
data from all years simultaneously. They produce estimates of key life-history parameters
such as annual productivity and survival.
Analyses for univoltine species, with only one generation each year, extend to bivoltine
species, with two annual broods. In the latter case we estimate the productivities of each
generation separately, and also devise extended indices which indicate the contributions
made from different generations.
We demonstrate the performance of the models using count data for UK butterfly species,
and compare with current procedures which use generalized additive models. We may incor-
orate relevant covariates within the model, and illustrate using northing and measures of
temperature. Consistent patterns are demonstrated for multiple species. This generates a
variety of hypotheses for further investigation, which have the potential to illuminate features
of butterfly phenology and demography which are at present poorly understood
A generalised abundance index for seasonal invertebrates
At a time of climate change and major loss of biodiversity, it is important to have efficient tools for monitoring populations. In this context, animal abundance indices play an important role. In producing indices for invertebrates, it is important to account for variation in counts within seasons. Two new methods for describing seasonal variation in invertebrate counts have recently been proposed; one is nonparametric, using generalized additive models, and the other is parametric, based on stopover models. We present a novel generalized abundance index which encompasses both parametric and nonparametric approaches. It is extremely efficient to compute this index due to the use of concentrated likelihood techniques. This has particular relevance for the analysis of data from long-term extensive monitoring schemes with records for many species and sites, for which existing modeling techniques can be prohibitively time consuming. Performance of the index is demonstrated by several applications to UK Butterfly Monitoring Scheme data. We demonstrate the potential for new insights into both phenology and spatial variation in seasonal patterns from parametric modeling and the incorporation of covariate dependence,
which is relevant for both monitoring and conservation. Associated R code is available on the journal website
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