Low power laser generated ultrasound : signal processing for time domain data acquisition

The use of low power modulated laser diode systems has previously been established as a suitable method for non-destructive laser generation of ultrasound. Using a quasi-continuous optical excitation amplified by an erbium-doped fibre amplifier (EDFA) allows flexible generation of ultrasonic waves, offering control of further parameters such as the frequency content or signal shape. In addition, pseudo-random binary sequences (PRBS) can be used to improve the detected impulse response. Here we compare two sequences, the m-sequence and the Golay code, and discuss the advantages and practical limits of their application with laser diode based optical excitation of ultrasound

The changes in chemical composition during development of the bovine nuchal ligament

Whole bovine nuchal ligaments, or portions thereof (in the case of commercially valuable animals), were obtained from 45 animals (28 fetal and 17 postnatal) ranging in age from 110 days of gestation to 10 yr. Insoluble elastin was quantitatively prepared from the fresh ligaments by extraction with hot alkali and by a combination of multiple extractions with alkaline buffer and then repeated autoclaving. When adult samples were examined, the yields of insoluble residue by these two methods were very similar, but with young fetal samples the second method gave significantly higher values, because of incomplete purification of the elastin residue. The changes in the concentration of collagen, alkali-insoluble elastin, and DNA have been examined. DNA concentration, and, thus, cell population density, fell progressively during the fetal period of development, to reach a steady value soon after birth. Collagen appeared in appreciable quantities before elastin, but its concentration was rapidly halved at about the time of birth. Insoluble elastin concentration was low until the end of the 7th fetal month, at which time it began to rise rapidly. The rate of increase in elastin concentration remained high throughout the next 10–12 wk, by which time the adult value had been reached. Quantitative studies, on the basis of the whole ligament, showed that the total cell content rises to a maximum at birth, but falls soon after to a level about half that at birth. Total collagen production and elastin deposition continue at a steady, maximal rate over the interval from 235 days of gestation to the end of the 1st postnatal month. It is concluded that the immediate postnatal period would be the most favorable phase in which to attempt the isolation of the soluble precursor elastin

Low power laser generated ultrasound : signal processing for time domain data acquisition

The use of low power modulated laser diode systems has previously been established as a suitable method for non-destructive laser generation of ultrasound. Using a quasi-continuous optical excitation amplified by an erbium-doped fibre amplifier (EDFA) allows flexible generation of ultrasonic waves, offering control of further parameters such as the frequency content or signal shape. In addition, pseudo-random binary sequences (PRBS) can be used to improve the detected impulse response. Here we compare two sequences, the m-sequence and the Golay code, and discuss the advantages and practical limits of their application with laser diode based optical excitation of ultrasound

Increasing serum calcium levels and recent return from transplantation as clues to the tuberculous nature of refractory peritoneal dialysis peritonitis

Peritoneal tuberculosis is an uncommon complication of peritoneal dialysis in Europe. It is more common in Asian immigrants. A delayed diagnosis is frequent and impairs patient outcomes. We present two cases of peritoneal tuberculosis with common features that may help suspect the disease early countries with a low incidence. Both patients were females (of Spanish origin) who had recently restarted peritoneal dialysis following kidney transplantation. Both developed bacterial peritonitis clinically that was refractory to conventional antibiotics, despite clearance of bacteria. Both stopped calcium-containing phosphate binders because of increasing serum calcium that in one case led to frank hypercalcemia that persisted despite low calcium dialysate. Peritoneal biopsy was the first positive test in both cases. This report emphasizes the recent return from transplantation and rising serum calcium levels as features that should alert the physician of a potential underlying tuberculous peritonitisGrant support: ISCII and FEDER funds FIS PS09/00447, PI13/00047, ISCIII-RETIC REDinREN/RD12/0021/0001, Comunidad de Madrid/CIFRA/ S2010/BMD-2378. Salary support: FIS Rio Hortega to BFF, CMC, LRO, Programa Intensificación Actividad Investigadora (ISCIII/Agencia Laín- Entralgo/CM) to A

A note on brain actuated spelling with the Berlin brain-computer interface

Brain-Computer Interfaces (BCIs) are systems capable of decoding neural activity in real time, thereby allowing a computer application to be directly controlled by the brain. Since the characteristics of such direct brain-tocomputer interaction are limited in several aspects, one major challenge in BCI research is intelligent front-end design. Here we present the mental text entry application ‘Hex-o-Spell’ which incorporates principles of Human-Computer Interaction research into BCI feedback design. The system utilises the high visual display bandwidth to help compensate for the extremely limited control bandwidth which operates with only two mental states, where the timing of the state changes encodes most of the information. The display is visually appealing, and control is robust. The effectiveness and robustness of the interface was demonstrated at the CeBIT 2006 (world’s largest IT fair) where two subjects operated the mental text entry system at a speed of up to 7.6 char/min

Mutual assessment in the social programmer ecosystem: an empirical investigation of developer profile aggregators

The multitude of social media channels that programmers can use to participate in software development has given rise to online developer profiles that aggregate activity across many services. Studying members of such developer profile aggregators, we found an ecosystem that revolves around the social programmer. Developers are assessing each other to evaluate whether other developers are interesting, worth following, or worth collaborating with. They are self-conscious about being assessed, and thus manage their public images. They value passion for software development, new technologies, and learning. Some recruiters participate in the ecosystem and use it to find candidates for hiring; other recruiters struggle with the interpretation of signals and issues of trust. This mutual assessment is changing how software engineers collaborate and how they advance their skills.Leif Singer, Fernando Figueira Filho, Brendan Cleary, Christoph Treude, Margaret-Anne Storey, Kurt Schneide

GHRS and ORFEUS-II Observations of the Highly Ionized Interstellar Medium Toward ESO141-055

We present Goddard High Resolution Spectrograph and ORFEUS-II measurements of Si IV, CIV, N V, and O VI absorption in the interstellar medium of the Galactic disk and halo toward the nucleus of the Seyfert galaxy ESO141-055. The high ionization absorption is strong, with line strengths consistent with the spectral signature expected for hot (log T = 5-6) collisionally ionized gas in either a ``Galactic fountain'' or an inhomogeneous medium containing a mixture of conductive interfaces and turbulent mixing layers. The total O VI column density of log N ~ 15 suggests that the scale height of O VI is large (>3 kpc) in this direction. Comparison of the high ion column densities with measurements for other sight lines indicates that the highly ionized gas distribution is patchy. The amount of O VI perpendicular to the Galactic plane varies by at least a factor of ~4 among the complete halo sight lines thus far studied. In addition to the high ion absorption, lines of low ionization species are also present in the spectra. With the possible exception of Ar I, which may have a lower than expected abundance resulting from partial photoionization of gas along the sight line, the absorption strengths are typical of those expected for the warm, neutral interstellar medium. The sight line intercepts a cold molecular cloud with log N(H2) ~ 19. The cloud has an identifiable counterpart in IRAS 100-micron emission maps of this region of the sky. We detect a Ly-alpha absorber associated with ESO141-055 at z = 0.03492. This study presents an enticing glimpse into the interstellar and intergalactic absorption patterns that will be observed at high spectral resolution by the Far Ultraviolet Spectroscopic Explorer.Comment: 24 pages + 8 figures, uses aaspp4.sty. Accepted for publication in Ap

Cryogenic microstripline-on-Kapton microwave interconnects

Simple broadband microwave interconnects are needed for increasing the size of focal plane heterodyne radiometer arrays. We have measured loss and cross-talk for arrays of microstrip transmission lines in flex circuit technology at 297 and 77 K, finding good performance to at least 20 GHz. The dielectric constant of Kapton substrates changes very little from 297 to 77 K, and the electrical loss drops. The small cross-sectional area of metal in a printed circuit structure yields overall thermal conductivities similar to stainless steel coaxial cable. Operationally, the main performance tradeoffs are between crosstalk and thermal conductivity. We tested a patterned ground plane to reduce heat flux.Comment: 3 pages, 3 figures, submitted to The Review of Scientific Instrument

Observations of total peroxy nitrates and aldehydes: measurement interpretation and inference of OH radical concentrations

We describe measurements of total peroxy nitrates (ΣPNs), NO₂, O₃ and several aldehydes at Granite Bay, California, during the Chemistry and Transport of the Sacramento Urban Plume-2001 (CATSUP 2001) campaign, from 19 July–16 September 2001. We observed a strong photochemically driven variation of ΣPNs during the day with the median of 1.2 ppb at noon. Acetaldehyde, pentanal, hexanal and methacrolein had median abundances in the daytime of 1.2 ppb, 0.093 ppb, 0.14 ppb, and 0.27 ppb, respectively. We compare steady state and time dependent calculations of the dependence of ΣPNs on aldehydes, OH, NO and NO₂ showing that the steady state calculations are accurate to ±30% between 10:00 and 18:00 h. We use the steady state calculation to investigate the composition of ΣPNs and the concentration of OH at Granite Bay. We find that PN molecules that have never been observed before make up an unreasonably large fraction of the ΣPNs unless we assume that there exists a PAN source that is much larger than the acetaldehyde source. We calculate that OH at the site varied between 2 and 7×10⁶ molecule cm^−3 at noon during the 8 weeks of the experiment