Dose reduction to normal tissues as compared to the gross tumor by using intensity modulated radiotherapy in thoracic malignancies

BACKGROUND AND PURPOSE: Intensity modulated radiotherapy (IMRT) is a powerful tool, which might go a long way in reducing radiation doses to critical structures and thereby reduce long term morbidities. The purpose of this paper is to evaluate the impact of IMRT in reducing the dose to the critical normal tissues while maintaining the desired dose to the volume of interest for thoracic malignancies. MATERIALS AND METHODS: During the period January 2002 to March 2004, 12 patients of various sites of malignancies in the thoracic region were treated using physical intensity modulator based IMRT. Plans of these patients treated with IMRT were analyzed using dose volume histograms. RESULTS: An average dose reduction of the mean values by 73% to the heart, 69% to the right lung and 74% to the left lung, with respect to the GTV could be achieved with IMRT. The 2 year disease free survival was 59% and 2 year overall survival was 59%. The average number of IMRT fields used was 6. CONCLUSION: IMRT with inverse planning enabled us to achieve desired dose distribution, due to its ability to provide sharp dose gradients at the junction of tumor and the adjacent critical organs

Operational management of the cane infield wagon: Analysis of the cost of repair and maintenance

ABSTRACT In the mechanical harvesting of sugarcane, a self-propelled harvester is used in conjunction with an agricultural implement named infield wagon, which has the function of storing and transporting the harvested product. Much of the cost of sugarcane production comes from this operation (30 to 60%). Among the operational costs of agricultural machinery, the cost of repair and maintenance (CRM) is relevant. Therefore, the objective of this study was to determine the parameters of the CRM mathematical model based on the life (hours of use) for the infield wagon, using the method of the American Society of Agricultural and Biological Engineers (ASABE). These CRM models were obtained for two sets of infield wagon from different manufacturers and their costs over up to 12 years. The model was adjusted and then validated using descriptive statistics methods. Fitted CRM equations were different for each analyzed set of infield wagon and, therefore, are a valuable tool in the management of mechanization in sugarcane mills as it provides elements that can support decision-making of managers in the acquisition and management of agricultural implements.</jats:p

Operational management of the cane infield wagon: Analysis of the cost of repair and maintenance

In the mechanical harvesting of sugarcane, a self-propelled harvester is used in conjunction with an agricultural implement named infield wagon, which has the function of storing and transporting the harvested product. Much of the cost of sugarcane production comes from this operation (30 to 60%). Among the operational costs of agricultural machinery, the cost of repair and maintenance (CRM) is relevant. Therefore, the objective of this study was to determine the parameters of the CRM mathematical model based on the life (hours of use) for the infield wagon, using the method of the American Society of Agricultural and Biological Engineers (ASABE). These CRM models were obtained for two sets of infield wagon from different manufacturers and their costs over up to 12 years. The model was adjusted and then validated using descriptive statistics methods. Fitted CRM equations were different for each analyzed set of infield wagon and, therefore, are a valuable tool in the management of mechanization in sugarcane mills as it provides elements that can support decision-making of managers in the acquisition and management of agricultural implements.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Univ Estadual Campinas, Fac Engn Agr, Campinas, SP, BrazilUniv Fed Ceara, Fortaleza, CE, BrazilUniv Estadual Paulista, Campus Expt Sorocaba, Sorocaba, SP, BrazilASSISTE Engn Softwares, Piracicaba, SP, BrazilUniv Estadual Paulista, Campus Expt Sorocaba, Sorocaba, SP, Brazi

Operational management of the cane infield wagon: Analysis of the cost of repair and maintenance

ABSTRACT In the mechanical harvesting of sugarcane, a self-propelled harvester is used in conjunction with an agricultural implement named infield wagon, which has the function of storing and transporting the harvested product. Much of the cost of sugarcane production comes from this operation (30 to 60%). Among the operational costs of agricultural machinery, the cost of repair and maintenance (CRM) is relevant. Therefore, the objective of this study was to determine the parameters of the CRM mathematical model based on the life (hours of use) for the infield wagon, using the method of the American Society of Agricultural and Biological Engineers (ASABE). These CRM models were obtained for two sets of infield wagon from different manufacturers and their costs over up to 12 years. The model was adjusted and then validated using descriptive statistics methods. Fitted CRM equations were different for each analyzed set of infield wagon and, therefore, are a valuable tool in the management of mechanization in sugarcane mills as it provides elements that can support decision-making of managers in the acquisition and management of agricultural implements

Operational management of the cane infield wagon: Analysis of the cost of repair and maintenance

<div><p>ABSTRACT In the mechanical harvesting of sugarcane, a self-propelled harvester is used in conjunction with an agricultural implement named infield wagon, which has the function of storing and transporting the harvested product. Much of the cost of sugarcane production comes from this operation (30 to 60%). Among the operational costs of agricultural machinery, the cost of repair and maintenance (CRM) is relevant. Therefore, the objective of this study was to determine the parameters of the CRM mathematical model based on the life (hours of use) for the infield wagon, using the method of the American Society of Agricultural and Biological Engineers (ASABE). These CRM models were obtained for two sets of infield wagon from different manufacturers and their costs over up to 12 years. The model was adjusted and then validated using descriptive statistics methods. Fitted CRM equations were different for each analyzed set of infield wagon and, therefore, are a valuable tool in the management of mechanization in sugarcane mills as it provides elements that can support decision-making of managers in the acquisition and management of agricultural implements.</p></div

Sars-Cov-2 Wastewater Surveillance for Public Health Action: Connecting Perspectives From Wastewater Researchers and Public Health Officials During a Global Pandemic

Wastewater surveillance for SARS-CoV-2 has garnered extensive public attention during the COVID-19 pandemic as a proposed complement to existing disease surveillance systems. Over the past year, environmental microbiology and engineering researchers have advanced methods for detection and quantification of SARS-CoV-2 viral RNA in untreated sewage and demonstrated that the trends in wastewater are correlated with trends in cases reported days to weeks later depending on the location. At the start of the pandemic, the virus was also detected in wastewater in locations prior to known cases. Despite the promise of wastewater surveillance, for these measurements to translate into useful public health tools, it is necessary to bridge the barriers between researchers and the public health responders who will ultimately use the data. Here we describe the key uses, barriers, and applicability of SARS-CoV-2 wastewater surveillance for supporting public health decisions and actions. This perspective was formed from a multidisciplinary group of environmental microbiology, engineering, wastewater, and public health experts, as well as from opinions shared during three focus group discussions with officials from ten state and local public health agencies. The key barriers to use of wastewater surveillance data identified were: (1) As a new data source, most public health agencies are not yet comfortable interpreting wastewater data; (2) Public health agencies want to see SARS-CoV-2 wastewater data in their own communities to gain confidence in its utility; (3) New institutional knowledge and increased capacity is likely needed to sustain wastewater surveillance systems; and (4) The ethics of wastewater surveillance data collection, sharing, and use are not yet established. Overall, while wastewater surveillance to assess community infections is not a new idea, by addressing these barriers, the COVID-19 pandemic may be the initiating event that turns this emerging public health tool into a sustainable nationwide surveillance system

SuN: Summing NaI(Tl) gamma-ray detector for capture reaction measurements

High demand for nuclear reaction cross-section measurements relevant for astrophysical processes requires the development of new experimental techniques that allow for investigation of, often very low, cross-sections. For this purpose, a new 4 pi Summing Nal(Tl) detector (SuN) has been constructed, which is an 8-fold segmented Nal(Tl) barrel read by 24 photomultipliers. The design of the detector will be presented and detailed results of the commissioning experiments utilizing standard calibration sources and known Al-27(p,gamma)Si-28 resonances will be discussed. (C) 2012 Elsevier B.V. All rights reserved

The Green Print: Advancement of Environmental Sustainability in Healthcare

Healthcare is a major emitter of environmental pollutants that adversely affect health. Within the healthcare community, awareness of these effects is low, and recognition of the duty to address them is only beginning to gain traction. Healthcare sustainability science explores dimensions of resource consumption and environmental emissions associated with healthcare activities. This emerging field provides tools and metrics to quantify the unintended consequences of healthcare delivery and evaluate effective approaches that improve patient safety while protecting public health. This narrative review describes the scope of healthcare sustainability research, identifies knowledge gaps, introduces a framework for applications of existing research methods and tools to the healthcare context, and establishes research priorities to improve the environmental performance of healthcare services. The framework was developed through review of the current state of healthcare sustainability science and expert consensus by the Working Group for Environmental Sustainability in Clinical Care. Key recommendations include: development of a comprehensive life cycle inventory database for medical devices and drugs; application of standardized sustainability performance metrics at the clinician, hospital/health system, and national levels; revision of infection control standards driving non-evidence-based uptake of single-use disposable devices; call for increased federal research funding; and formation of a Global Commission on the Advancement of Environmental Sustainability in Healthcare. There is an urgent need for research that informs policy and practice to address the public health crisis arising from healthcare pollution. A transformational vision is required to align research priorities to achieve a sustainable healthcare system that advances quality, safety and value