Age specific sex differences in BMI and skin fold thickness among children of Kazaure Emirate, Nigeria

An important phenomenon occurring in human population is the variation in their physical morphology. The physical dimensions of human body are influenced by geographical, racial, age and gender factors. Physical anthropometry provides the technique by which human body dimensions can be evaluated and measured. The aim of the study was to determine age specific sex differences in height, weight, BMI and skin fold thickness among children aged 5- 12 years from Kazaure emirate, Jigawa State, Nigeria. The objective of the study was to investigate sexual dimorphism in the measured variables. A total of 1212 primary school pupils aged 5-12 years (659 males and 553 females) were involved. All the anthropometric variables were taken using standard protocols. An independent t-test was used to determine gender differences using SPSS version 20.0and P ≤ 0.05 considered a level of significance. The results showed a significant gender difference in height and weight at age of 8 years (P = 0.009) and (P< 0.001), respectively. For bicep skin fold thickness (BSF), the gender difference was observed at 7 to 12years of age with (P< 0.001). Similar pattern in triceps TSF) and suprailiac (SISF), showed significant difference at age six (P< 0.001) and (P =0.01), respectively. All ages showed differences in subscapular skin fold thickness (SSF)(P< 0.001). In the SSF, female had higher mean value while for height and weight the reverse trend was the case. In conclusion, the gender differences in SSF may be linked with higher adipose tissue in female than in the male counterparts in childhood.Keywords: Anthropometry, BMI, Skin fold thickness, age, sex, Nigeri

Proximate composition and the mineral contents of soya beans (Glycine max) available in Kano State, Nigeria

Soya bean is an important source of high-quality protein and oil, as well as other nutritious substances. The higher the content of these nutritious substances in a given soya bean, the higher it’s quality. The mineral and proximate contents of the variety of soya beans available in Kano state, Nigeria, were determined using standard procedures. The percentage (%) proximate composition was found to be Moisture 8.13%, Crude Protein 39.24%, Crude Fibre 6.84%, Crude Lipid 30.31%, Ash 4.61%, and Carbohydrate 5.08%. While the average mineral contents (%) were found to be 0.003 (Na), 0.216 (K), 0.281 (Mg), 0.324 (Ca), 0.722 (P), 0.003 (Zn), 0.002 (Cu), 0.291 (Mn) and 0.018 (Fe). The result is an indication of the nutritional importance of soya beans, and thus its production and quality require to be improved.Keywords: Mineral content, Nutritional value, Proximate composition, Soya bean

MHD Flow and Heat Transfer in a Power-law Liquid Film at a Porous Surface in the Presence of Thermal Radiation

In this paper, the effects of variable thermal conductivity and thermal radiation on the MHD flow and heat transfer of a non-Newtonian power-law liquid film at a horizontal porous sheet in the presence of viscous dissipation is studied. The governing time dependent boundary layer equations are transformed to coupled, non-linear ordinary differential equations with power-law index, unsteady parameter, film thickness, magnetic parameter, injection parameter, variable thermal conductivity parameter, thermal radiation parameter, the Prandtl number and the Eckert number. These coupled non-linear equations are solved numerically by an implicit, finite difference scheme known as the Keller box method. The obtained numerical results for velocity and temperature profiles are presented graphically. Also, the obtained results of our study for some special cases are compared with the previously published results, and the results are found to be in very good agreement. The effects of unsteady parameter on the skin friction, wall-temperature gradient and the film thickness are explored for different values of the power-law index and the magnetic parameter. The results obtained reveal many interesting behaviors that warrant further study of the equations related to non-Newtonian fluid phenomena, especially the shear-thinning phenomena

PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae

About one-fifth of the genes in the budding yeast are essential for haploid viability and cannot be functionally assessed using standard genetic approaches such as gene deletion. To facilitate genetic analysis of essential genes, we and others have assembled collections of yeast strains expressing temperature-sensitive (ts) alleles of essential genes. To explore the phenotypes caused by essential gene mutation we used a panel of genetically engineered fluorescent markers to explore the morphology of cells in the ts strain collection using high-throughput microscopy. Here, we describe the design and implementation of an online database, PhenoM (Phenomics of yeast Mutants), for storing, retrieving, visualizing and data mining the quantitative single-cell measurements extracted from micrographs of the ts mutant cells. PhenoM allows users to rapidly search and retrieve raw images and their quantified morphological data for genes of interest. The database also provides several data-mining tools, including a PhenoBlast module for phenotypic comparison between mutant strains and a Gene Ontology module for functional enrichment analysis of gene sets showing similar morphological alterations. The current PhenoM version 1.0 contains 78 194 morphological images and 1 909 914 cells covering six subcellular compartments or structures for 775 ts alleles spanning 491 essential genes. PhenoM is freely available at http://phenom.ccbr.utoronto.ca/

African-American inflammatory bowel disease in a Southern U.S. health center

<p>Abstract</p> <p>Background</p> <p>Inflammatory Bowel Diseases (IBD) remain significant health problems in the US and worldwide. IBD is most often associated with eastern European ancestry, and is less frequently reported in other populations of African origin e.g. African Americans ('AAs'). Whether AAs represent an important population with IBD in the US remains unclear since few studies have investigated IBD in communities with a majority representation of AA patients. The Louisiana State University Health Sciences Center in Shreveport (LSUHSC-S) is a tertiary care medical center, with a patient base composed of 58% AA and 39% Caucasian (W), ideal for evaluating racial (AA vs. W) as well and gender (M vs. F) influences on IBD.</p> <p>Methods</p> <p>In this retrospective study, we evaluated 951 visits to LSUHSC-S for IBD (between 2000 to 2008) using non-identified patient information based on ICD-9 medical record coding (Crohn's disease 'CD'-555.0- 555.9 and ulcerative colitis 'UC'-556.0-556.9).</p> <p>Results</p> <p>Overall, there were more cases of CD seen than UC. UC and CD affected similar ratios of AA and Caucasian males (M) and females (F) with a rank order of WF > WM > AAF > AAM. Interestingly, in CD, we found that annual visits per person was the highest in AA M (10.7 ± 1.7); significantly higher (* -p < 0.05) than in WM (6.3 ± 1.0). Further, in CD, the female to male (F: M) ratio in AA was significantly higher (*- p < 0.05) (1.9 ± 0.2) than in Caucasians (F:M = 1.3 ± 0.1) suggesting a female dominance in AACD; no differences were seen in UC F: M ratios.</p> <p>Conclusion</p> <p>Although Caucasians still represent the greatest fraction of IBD (~64%), AAs with IBD made up >1/3 (36.4%) of annual IBD cases from 2000-2008 at LSUHSC-S. Further studies on genetic and environments risks for IBD risk in AAs are needed to understand differences in presentation and progression in AAs and other 'non-traditional' populations.</p

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries