Pennsylvania Folklife Vol. 25, Folk Festival Supplement

• Quilts, Quilts, Quilts • America\u27s Heritage is Endowed with Contributions of the Pennsylvania Dutch • The Hospitality Tent: H is for Help - That\u27s What it\u27s all About • Pottery: A Folk Art Expressing the Most in Simplest Terms • It Never Rains on our Parade - On the Fourth of July • Vegetable Dyeing at the Kutztown Folk Festival • Festival Focus • Folk Festival Program • Festival Foods: The Original Touch of the Dutch • Ursinus College Studies at the Festival • Behind the Scenes of We Like Our Country, But We Love Our God • Reverse Glass Tinsel Painting • Tin, Tole and Independencehttps://digitalcommons.ursinus.edu/pafolklifemag/1069/thumbnail.jp

Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities

Background Epidermal growth factor receptor inhibitors (EGFRI) produce various dermatologic side effects in the majority of patients, and guidelines are crucial for the prevention and treatment of these untoward events. The purpose of this panel was to develop evidence-based recommendations for EGFRI-associated dermatologic toxicities. Methods A multinational, interdisciplinary panel of experts in supportive care in cancer reviewed pertinent studies using established criteria in order to develop first-generation recommendations for EGFRI-associated dermatologic toxicities. Results Prophylactic and reactive recommendations for papulopustular (acneiform) rash, hair changes, radiation dermatitis, pruritus, mucositis, xerosis/fissures, and paronychia are presented, as well as general dermatologic recommendations when possible. Conclusion Prevention and management of EGFRI-related dermatologic toxicities is critical to maintain patients’ health-related quality of life and dose intensity of antineoplastic regimens. More rigorous investigation of these toxicities is warranted to improve preventive and treatment strategies

Petrology of Submarine Lavas from Kilauea\u27s Puna Ridge, Hawaii

We have studied 30 quenched tholeiitic lava flows recovered by 20 dredge hauls and one submersible dive along Puna Ridge, the submarine part of the East Rift Zone of Kilauea Volcano, Hawaii Glass grains from numerous additional flows were recovered in turbidite sands cored in the Hawaiian Trough. These quenched lavas document variable primary magma compositions; olivine and multiphase crystallization and fractionation; degassing; wall-rock stoping and assimilation; mixing in the crustal reservoir and the rift zone; entrainment of olivine xenocrysts from a hot, ductile, olivine cumulate body; and disruption of gabbro wallrocks in the rift zone. Glass grains in turbidite sands contain up to 15⋅0wt% MgO, in contrast to \u3c 7⋅0wt% MgO for the sampled glass rinds on lavas. The most forsteritic olivine phenocryst (F090·7) is in equilibrium with primary Kilauea liquid containing an average 16⋅5 wt% MgO, but ranging from 13⋅4 to 18⋅4%. Lavas and glass grains have more restricted P2O5/K2O and TiO2/K2O than glass inclusions in olivine, because more diverse liquids trapped as glass inclusions are mixed and homogenized before eruption. Variable trace element compositions in glass grains and whole rocks indicate that the primary liquids form by partial melting of mantle sources retaining clinopyroxene and garnet. Orthopyroxene xenocrysts formed at moderate pressures provide evidence for a sub-crustal staging zone. Chromite and olivine crystallize in the crustal magma reservoir as the liquid cools from an average 1346°C to ∼1170°C. Low viscosities of the primary liquids (0·4 Pas) facilitate olivine settling, and the crystallized olivine forms an olivine cumulate body at the base of the reservoir. Olivine is deformed as the hot ductile dunite body flows down and away from the summit. This flow drives instability of the Hilina landslide on Kilauea. Dikes intrude the dunite, and magma flowing through the dikes disaggregates and entrains olivine xenocrysts in Puna Ridge magmas. Primary liquids pond at or near the base of Kilauea\u27s crustal reservoir because they are denser than more fractionated liquids that occupy the upper parts of the reservoir. The sulfur and water contents of glass rinds indicate that fractionated liquids near the top of the reservoir degas at low pressure, a process that increases their density and causes them to sink to levels where they mix with resident undegassed, near-primary liquid. The fractionated liquids near the top of the magma reservoir acquire excess Cl, owing to assimilation of hydrothermally altered roofrocks. Magma flowing into the rift zone encounters and mixes with low-temperature, multiphase-fractionated melt. The mixed magmas typically contain rare orthopyroxene, plagioclase as sodic as andesine, olivine as fayalitic as F075 and Fe-rich augite derived from the fractionated magma. Magma flowing through dikes also dislodged fragments of gabbroic wallrocks that occur as xenoliths. The interrelations in the Kilauean submarine lavas between host glass and glass inclusion compositions, volatile contents and mineral chemistry reveal an extraordinarily complex sequence of petrogenetic processes and events that are difficult or impossible to determine in subaerial Kilauea lavas because of crystallization, reequilibration and degassing during or after their eruption

Understanding the concept of chemotherapy-related nausea: The patient experience

The aim of this study was to explore the experience of chemotherapy-related nausea in patients with cancer. A qualitative study was carried out with 17 patients who had experienced nausea during their chemotherapy in the UK and USA. Nausea was described as distressing and complex symptom. Patients attempted to construct an understanding of nausea using cognitive processes such as analysing their experience of nausea and related symptoms, attributing causation to nausea and comparing their experiences not only to their own expectations, but also to others' symptom experiences. A number of concurrent and associated symptoms linked with nausea were identified. Preliminary evidence emerged for nausea as part of a cluster of symptoms. Anti-emetic medication, provider-directed management strategies and self-management strategies were used by patients to minimize the effects of nausea. Self-management techniques, such as dietary strategies, were rooted in participants' understanding of nausea and their beliefs about what caused nausea, and there was little evidence of guidance from professionals beyond advice about medication management. This study reveals some of the complexities behind chemotherapy-induced nausea, including a potential symptom cluster, and contributes towards a clearer understanding of this symptom and its effects on patients' lives. © 2008 The Authors

Clinical practice guidelines for the prevention and treatment of acute and late radiation reactions from the MASCC Skin Toxicity Study Group

10.1007/s00520-013-1896-2Supportive Care in Cancer21102933-2948SCCA