2,844 research outputs found
Temperature Profiles in Hamiltonian Heat Conduction
We study heat transport in the context of Hamiltonian and related stochastic
models with nearest-neighbor coupling, and derive a universal law for the
temperature profiles of a large class of such models. This law contains a
parameter , and is linear only when . The value of
depends on energy-exchange mechanisms, including the range of motion of tracer
particles and their times of flight.Comment: Revised text, same results Second revisio
The p-periodicity of the groups GL (n, Os(K)) and SL(n, Os(K))
In this paper we investigate the p-periodicity of the S-arithmetic groups G = GL(n, Os(K)) and G1 = SL(n, Os(K)) where Os(K) is the ring of S-integers of a number field K (cf. [12, 13]; S is a finite set of places in K including the infinite places). These groups are known to be virtually of finite (cohomological) dimension, and thus the concept of p-periodicity is defined; it refers to a rational prime p and to the p-primary component Ĥi(G, A, p) of the Farrell-Tate cohomology Ĥi(G, A) with respect to an arbitrary G-module A. We recall that Ĥi coincides with the usual cohomology Hi for all i above the virtual dimension of G, and that in the case of a finite group (i.e., a group of virtual dimension zero) the Ĥi, i , are the usual Tate cohomology groups. The group G is called p-periodic if Ĥi(G, A, p) is periodic in i, for all A, and the smallest corresponding period is then simply called the p-period of G. If G has no p-torsion, the p-primary component of all its Ĥi is 0, and thus G is trivially p-periodi
How to avoid potential pitfalls in recurrence plot based data analysis
Recurrence plots and recurrence quantification analysis have become popular
in the last two decades. Recurrence based methods have on the one hand a deep
foundation in the theory of dynamical systems and are on the other hand
powerful tools for the investigation of a variety of problems. The increasing
interest encompasses the growing risk of misuse and uncritical application of
these methods. Therefore, we point out potential problems and pitfalls related
to different aspects of the application of recurrence plots and recurrence
quantification analysis
Remarks on Bootstrap Percolation in Metric Networks
We examine bootstrap percolation in d-dimensional, directed metric graphs in
the context of recent measurements of firing dynamics in 2D neuronal cultures.
There are two regimes, depending on the graph size N. Large metric graphs are
ignited by the occurrence of critical nuclei, which initially occupy an
infinitesimal fraction, f_* -> 0, of the graph and then explode throughout a
finite fraction. Smaller metric graphs are effectively random in the sense that
their ignition requires the initial ignition of a finite, unlocalized fraction
of the graph, f_* >0. The crossover between the two regimes is at a size N_*
which scales exponentially with the connectivity range \lambda like_* \sim
\exp\lambda^d. The neuronal cultures are finite metric graphs of size N \simeq
10^5-10^6, which, for the parameters of the experiment, is effectively random
since N<< N_*. This explains the seeming contradiction in the observed finite
f_* in these cultures. Finally, we discuss the dynamics of the firing front
Recommended from our members
ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome.
Backgrounds and aims4-6 million people die of enteric infections each year. After invading intestinal epithelial cells, enteric bacteria encounter phagocytes. However, little is known about how phagocytes internalize the bacteria to generate host responses. Previously, we have shown that BAI1 (Brain Angiogenesis Inhibitor 1) binds and internalizes Gram-negative bacteria through an ELMO1 (Engulfment and cell Motility protein 1)/Rac1-dependent mechanism. Here we delineate the role of ELMO1 in host inflammatory responses following enteric infection.MethodsELMO1-depleted murine macrophage cell lines, intestinal macrophages and ELMO1 deficient mice (total or myeloid-cell specific) was infected with Salmonella enterica serovar Typhimurium. The bacterial load, inflammatory cytokines and histopathology was evaluated in the ileum, cecum and spleen. The ELMO1 dependent host cytokines were detected by a cytokine array. ELMO1 mediated Rac1 activity was measured by pulldown assay.ResultsThe cytokine array showed reduced release of pro-inflammatory cytokines, including TNF-α and MCP-1, by ELMO1-depleted macrophages. Inhibition of ELMO1 expression in macrophages decreased Rac1 activation (~6 fold) and reduced internalization of Salmonella. ELMO1-dependent internalization was indispensable for TNF-α and MCP-1. Simultaneous inhibition of ELMO1 and Rac function virtually abrogated TNF-α responses to infection. Further, activation of NF-κB, ERK1/2 and p38 MAP kinases were impaired in ELMO1-depleted cells. Strikingly, bacterial internalization by intestinal macrophages was completely dependent on ELMO1. Salmonella infection of ELMO1-deficient mice resulted in a 90% reduction in bacterial burden and attenuated inflammatory responses in the ileum, spleen and cecum.ConclusionThese findings suggest a novel role for ELMO1 in facilitating intracellular bacterial sensing and the induction of inflammatory responses following infection with Salmonella
On Turing dynamical systems and the Atiyah problem
Main theorems of the article concern the problem of M. Atiyah on possible
values of l^2-Betti numbers. It is shown that all non-negative real numbers are
l^2-Betti numbers, and that "many" (for example all non-negative algebraic)
real numbers are l^2-Betti numbers of simply connected manifolds with respect
to a free cocompact action. Also an explicit example is constructed which leads
to a simply connected manifold with a transcendental l^2-Betti number with
respect to an action of the threefold direct product of the lamplighter group
Z/2 wr Z. The main new idea is embedding Turing machines into integral group
rings. The main tool developed generalizes known techniques of spectral
computations for certain random walk operators to arbitrary operators in
groupoid rings of discrete measured groupoids.Comment: 35 pages; essentially identical to the published versio
Modularity and Optimality in Social Choice
Marengo and the second author have developed in the last years a geometric
model of social choice when this takes place among bundles of interdependent
elements, showing that by bundling and unbundling the same set of constituent
elements an authority has the power of determining the social outcome. In this
paper we will tie the model above to tournament theory, solving some of the
mathematical problems arising in their work and opening new questions which are
interesting not only from a mathematical and a social choice point of view, but
also from an economic and a genetic one. In particular, we will introduce the
notion of u-local optima and we will study it from both a theoretical and a
numerical/probabilistic point of view; we will also describe an algorithm that
computes the universal basin of attraction of a social outcome in O(M^3 logM)
time (where M is the number of social outcomes).Comment: 42 pages, 4 figures, 8 tables, 1 algorithm
Topological aggregation, the twin paradox and the No Show paradox
International audienceConsider the framework of topological aggregation introduced by Chichilnisky (1980). We prove that in this framework the Twin Paradox and the No Show Paradox cannot be avoided. Anonymity and unanimity are not needed to obtain these results
Lyapunov exponents and transport in the Zhang model of Self-Organized Criticality
We discuss the role played by the Lyapunov exponents in the dynamics of
Zhang's model of Self-Organized Criticality. We show that a large part of the
spectrum (slowest modes) is associated with the energy transpor in the lattice.
In particular, we give bounds on the first negative Lyapunov exponent in terms
of the energy flux dissipated at the boundaries per unit of time. We then
establish an explicit formula for the transport modes that appear as diffusion
modes in a landscape where the metric is given by the density of active sites.
We use a finite size scaling ansatz for the Lyapunov spectrum and relate the
scaling exponent to the scaling of quantities like avalanche size, duration,
density of active sites, etc ...Comment: 33 pages, 6 figures, 1 table (to appear
- …
