1,043 research outputs found
Chronotherapy with 5-Fluorouracil (5-FU) and folinic acid (FA) in advanced colorectal carcinoma: Results of a chronopharmacologic phase I/II trial
Sequential epiretinal membrane removal with internal limiting membrane peeling in brilliant blue G-assisted macular surgery
Purpose
To assess the selectivity of brilliant blue G (BBG) staining by analysing the morphological components of unstained and stained tissue obtained during epiretinal membrane (ERM) removal with internal limiting membrane (ILM) peeling in BBG-assisted macular surgery.
Methods
Twenty-six surgical specimens were removed from 13 eyes with epiretinal gliosis during vitrectomy using BBG for ERM and ILM peeling. We included eyes with idiopathic macular pucker, idiopathic macular hole and vitreomacular traction syndrome. The dye was injected into the fluid-filled globe. Unstained and stained epiretinal tissue was harvested consecutively and placed into separate containers. All specimens were processed for conventional transmission electron microscopy.
Results
The first surgical specimen of all eyes showed no intraoperative staining with BBG and corresponded to masses of cells and collagen. The second surgical specimen demonstrated good staining characteristics and corresponded to the ILM in all patients included. In seven eyes, the ILM specimens were seen with minor cell proliferations such as single cells or a monolayer of cells. Myofibroblasts, fibroblasts and astrocytes were present. In five cases, native vitreous collagen fibrils were found at the ILM. In six of the eyes, ILM specimens were blank.
Conclusion
Our clinicopathological correlation underlines the selective staining properties of BBG. The residual ILM is selectively stained by BBG even when a small amount of cells and collagen adheres to its vitreal side. To reduce the retinal exposure to the dye, the surgeon might choose to remove the ERM without using the dye, followed by a BBG injection to identify residual ILM
Trobriander (Ost-Neuguinea, Trobriand Inseln, Kaile'una) Fadenspiele 'ninikula'
Sammelband 1, 1985-198
Trobriander (Ost-Neuguinea, Trobriand Inseln, Kaile'una) Fadenspiele 'ninikula'
Sammelband 1, 1985-198
Strong subadditivity inequality for quantum entropies and four-particle entanglement
Strong subadditivity inequality for a three-particle composite system is an
important inequality in quantum information theory which can be studied via a
four-particle entangled state. We use two three-level atoms in
configuration interacting with a two-mode cavity and the Raman adiabatic
passage technique for the production of the four-particle entangled state.
Using this four-particle entanglement, we study for the first time various
aspects of the strong subadditivity inequality.Comment: 5 pages, 3 figures, RevTeX4, submitted to PR
Mother-to-infant and father-to-infant initial emotional involvement
While infant attachment has been largely studied, parental attachment is still relatively unknown,
especially when referred to fathers. However, it is mainly recognised that parents’ emotional involvement
with the newborn contributes to the quality of the interaction and the care they provide. The
aim of this study was to study mother-to-infant and father-to-infant initial emotional involvement;
namely, differences between mothers and fathers and changes in mother’s emotions toward the
neonate within the first days after delivery. The Bonding Scale, an extended Portuguese version of
the ‘New Mother-to-Infant Bonding Scale’, was administered during the first two days after childbirth
to a sample of 315 mothers and 141 fathers (n = 456), at the Júlio Dinis Maternity Hospital
(Portugal). Most mothers and fathers show positive emotions and only a few of them showed
negative emotions toward the infant. Maternal and paternal emotional involvement toward the
newborn tend to be similar; nevertheless, fathers show less fear and better emotional involvement
with the neonate, while mothers are sadder and show more emotions not related to bonding. During
the first days following delivery, emotions not related to bonding, such as fear, seem to decrease in
mothers.Bial Foundation - Grant 58/02.Human Development and Health
Service of the Calouste Gulbenkian Foundation - Grant 48914
Testing foundations of quantum mechanics with photons
The foundational ideas of quantum mechanics continue to give rise to
counterintuitive theories and physical effects that are in conflict with a
classical description of Nature. Experiments with light at the single photon
level have historically been at the forefront of tests of fundamental quantum
theory and new developments in photonics engineering continue to enable new
experiments. Here we review recent photonic experiments to test two
foundational themes in quantum mechanics: wave-particle duality, central to
recent complementarity and delayed-choice experiments; and Bell nonlocality
where recent theoretical and technological advances have allowed all
controversial loopholes to be separately addressed in different photonics
experiments.Comment: 10 pages, 5 figures, published as a Nature Physics Insight review
articl
and Oxygen Stoichiometry: Structure, Resistivity, Fermi Surface Topology and Normal State Properties
(2212) single crystal samples
were studied using transmission electron microscopy (TEM), plane
() and axis () resistivity, and high resolution
angle-resolved ultraviolet photoemission spectroscopy (ARUPS). TEM reveals that
the modulation in the axis for doped 2212 is dominantly
of type that is not sensitive to the oxygen content of the system, and the
system clearly shows a structure of orthorhombic symmetry. Oxygen annealed
samples exhibit a much lower axis resistivity and a resistivity minimum at
K. He-annealed samples exhibit a much higher axis resistivity and
behavior below 300K. The Fermi surface (FS) of oxygen annealed
2212 mapped out by ARUPS has a pocket in the FS around the
point and exhibits orthorhombic symmetry. There are flat, parallel sections of
the FS, about 60\% of the maximum possible along , and about 30\%
along . The wavevectors connecting the flat sections are about
along , and about along , rather than . The symmetry of the near-Fermi-energy dispersing
states in the normal state changes between oxygen-annealed and He-annealed
samples.Comment: APS_REVTEX 3.0, 49 pages, including 11 figures, available upon
request. Submitted to Phys. Rev. B
Radiological anatomy of the ambient cistern in children
Ambient cistern (AC) is a thin extension of the subarachnoid space surrounding
the brainstem at the level of the mesencephalon and pons. Despite various
definitions, it constitutes an important landmark in clinical assessment of intracranial
volume reserve. Although it is indisputably useful, there exists no
defined standard for radiological examination for the dimensions and ranges
in specific age groups. This paper aims to describe the ambient cistern anatomically
and give the ranges of dimensions for proper radiological interpretation.
The study was performed on 160 axial computed tomography (CT) examinations
of Polish children of both sexes, aged 1-18 years, admitted to the
hospital because of mild brain concussion. Pictures were made using a Siemens
8-row CT scanner, without contrast administration. We estimated distances
at the level of the pons and midbrain, based on axial cross-sections,
according to standard radiological protocol. The parameters included the width
of the AC in its anterior and posterior part, the width of the tentorial notch,
and the distance from the pons and sella. All measurements were analyzed
statistically with StatSoft Statistica 8.0 software. The average width of the AC
differs between age groups. It is greatest at 1-3 years (2.8 ± 0.6 mm) and
lowest at 4-10 years (2.4 ± 0.6 mm). AC is more likely to be greater in its
anterior part in boys. The distance from the sella to the pons is greatest in 1-3-year-old girls (6.9 ± 1.3 mm), and the tentorial notch is widest in the 15-18-year-old group (24.6 ± 2.4 mm). Dimensions of the AC correlate with intracranial
reserve volume. This is particularly visible in the youngest children. Thin
and narrow AC is not always a sign of raised intracranial pressure. It may be
specific for the child’s age. (Folia Morphol 2010; 69, 2: 78-83
- …
