A Proper Motion Study of the Haro 6-10 Outflow: Evidence for a Subarcsecond Binary

We present single-dish and VLBI observations of an outburst of water maser emission from the young binary system Haro 6-10. Haro 6-10 lies in the Taurus molecular cloud and contains a visible T Tauri star with an infrared companion 1.3" north. Using the Very Long Baseline Array, we obtained five observations spanning 3 months and derived absolute positions for 20 distinct maser spots. Three of the masers can be traced over 3 or more epochs, enabling us to extract absolute proper motions and tangential velocities. We deduce that the masers represent one side of a bipolar outflow that lies nearly in the plane of the sky with an opening angle of ~45\deg. They are located within 50 mas of the southern component of the binary, the visible T Tauri star Haro 6-10S. The mean position angle on the sky of the maser proper motions (~220\deg) suggests they are related to the previously observed giant Herbig-Haro (HH) flow which includes HH410, HH411, HH412, and HH184A-E. A previously observed HH jet and extended radio continuum emission (mean position angle of ~190\deg) must also originate in the vicinity of Haro6-10S and represent a second, distinct outflow in this region. We propose that a yet unobserved companion within 150 mas of Haro6-10S is responsible for the giant HH/maser outflow while the visible star is associated with the HH jet. Despite the presence of H_2 emission in the spectrum of the northern component of the binary, Haro6-10N, none of outflows/jets can be tied directly to this young stellar object

Reconstruction of a first-order phase transition from computer simulations of individual phases and subphases

We present a new method for investigating first-order phase transitions using Monte Carlo simulations. It relies on the multiple-histogram method and uses solely histograms of individual phases. In addition, we extend the method to include histograms of subphases. The free energy difference between phases, necessary for attributing the correct statistical weights to the histograms, is determined by a detour in control parameter space via auxiliary systems with short relaxation times. We apply this method to a recently introduced model for structure formation in polypeptides for which other methods fail.Comment: 13 pages in preprint mode, REVTeX, 2 Figures available from the authors ([email protected], [email protected]

Host plant pubescence: Effect on silverleaf whitefly, Bemisia argentifolii, fourth instar and pharate adult dimensions and ecdysteroid titer fluctuations

The ability to generate physiologically synchronous groups of insects is vital to the performance of investigations designed to test insect responses to intrinsic and extrinsic stimuli. During a given instar, the silverleaf whitefly, Bemisia argentifolii, increase in depth but not in length or width. A staging system to identify physiologically synchronous 4(th) instar and pharate adult silverleaf whiteflies based on increasing body depth and the development of the adult eye has been described previously. This study determined the effect of host plant identity on ecdysteroid fluctuations during the 4(th) instar and pharate adult stages, and on the depth, length and width dimensions of 4(th) instar/pharate adult whiteflies. When grown on the pubescent-leafed green bean, tomato and poinsettia plants, these stages were significantly shorter and narrower, but attained greater depth than when grown on the glabrous-leafed cotton, collard and sweet potato plants. Thus, leaf pubescence is associated with reduced length and width dimensions, but increased depth dimensions in 4(th) Abbreviation: / EIA: enzyme immunoassa

Climate Vulnerability and the Cost of Debt

We use indices from the Notre Dame Global Adaptation Initiative to investigate the impact of climate vulnerability on bond yields. Our methodology invokes panel ordinary least squares with robust standard errors and principal component analysis. The latter serves to address the multicollinearity between a set of vulnerability measures. We find that countries with higher exposure to climate vulnerability, such as the member countries of the V20 climate vulnerable forum, exhibit 1.174 percent higher cost of debt on average. This effect is significant after accounting for a set of macroeconomic controls. Specifically, we estimate the incremental debt cost due to higher climate vulnerability, for the V20 countries, to have exceeded USD 62 billion over the last ten years. In other words, for every ten dollars they pay in interest cost, they pay another dollar for being climate vulnerable. We also find that a measure of social readiness, which includes education and infrastructure, has a negative and significant effect on bond yields, implying that social and physical investments can mitigate climate risk related debt costs and help to stabilize the cost of debt for vulnerable countries

Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth

A role for Hedgehog (Hh) signalling in the development of colorectal cancer (CRC) has been proposed. In CRC and other solid tumours, Hh ligands are upregulated; however, a specific Hh antagonist provided no benefit in a clinical trial. Here we use Hh reporter mice to show that downstream Hh activity is unexpectedly diminished in a mouse model of colitis-associated colon cancer, and that downstream Hh signalling is restricted to the stroma. Functionally, stroma-specific Hh activation in mice markedly reduces the tumour load and blocks progression of advanced neoplasms, partly via the modulation of BMP signalling and restriction of the colonic stem cell signature. By contrast, attenuated Hh signalling accelerates colonic tumourigenesis. In human CRC, downstream Hh activity is similarly reduced and canonical Hh signalling remains predominantly paracrine. Our results suggest that diminished downstream Hh signalling enhances CRC development, and that stromal Hh activation can act as a colonic tumour suppressor

Novel Analytical Calculation Method for the Non-Linear Ψ -i- Characteristic of Switched-Reluctance-Machines in Arbitrary Rotor Positions

Abstract The non-linear Ψ -i-characteristic is crucial for the design of switched reluctance machines. Known analytical calculations are based on complex models of the magnetic circuit or on functions needing a fitting procedure (using measured or FEM-calculated data). In this paper, a method is presented that requires only very few input data, which can be deduced easily from the geometry of the machine. Comparisons with measured data show an acceptable correlation for arbitrary rotor positions, qualifying this method to be used in the design stage of new drives