737 research outputs found
Effects of Interface Roughness Scattering on Radio Frequency Performance of Silicon Nanowire Transistors
The effects of an atomistic interface roughness in n-type silicon nanowire
transistors (SiNWT) on the radio frequency performance are analyzed. Interface
roughness scattering (IRS) is statistically investigated through a three
dimensional full-band quantum transport simulation based on the sp3d5s?*
tight-binding model. As the diameter of the SiNWT is scaled down below 3 nm,
IRS causes a significant reduction of the cut-off frequency. The fluctuations
of the conduction band edge due to the rough surface lead to a reflection of
electrons through mode-mismatch. This effect reduces the velocity of electrons
and hence the transconductance considerably causing a cut-off frequency
reduction
Magnetic excitations of the Cu quantum spin chain in SrCuPtO
We report the magnetic excitation spectrum as measured by inelastic neutron
scattering for a polycrystalline sample of SrCuPtO. Modeling the data
by the 2+4 spinon contributions to the dynamical susceptibility within the
chains, and with interchain coupling treated in the random phase approximation,
accounts for the major features of the powder-averaged structure factor. The
magnetic excitations broaden considerably as temperature is raised, persisting
up to above 100 K and displaying a broad transition as previously seen in the
susceptibility data. No spin gap is observed in the dispersive spin excitations
at low momentum transfer, which is consistent with the gapless spinon continuum
expected from the coordinate Bethe ansatz. However, the temperature dependence
of the excitation spectrum gives evidence of some very weak interchain
coupling.Comment: 9 pages, 5 figure
Fiber-bundle illumination: realizing high-degree time-multiplexed multifocal multiphoton microscopy with simplicity
High-degree time-multiplexed multifocal multiphoton microscopy was expected to provide a facile path to scanningless optical-sectioning and the fast imaging of dynamic three-dimensional biological systems. However, physical constraints on typical time multiplexing devices, arising from diffraction in the free-space propagation of light waves, lead to significant manufacturing difficulties and have prevented the experimental realization of high-degree time multiplexing. To resolve this issue, we have developed a novel method using optical fiber bundles of various lengths to confine the diffraction of propagating light waves and to create a time multiplexing effect. Through this method, we experimentally demonstrate the highest degree of time multiplexing ever achieved in multifocal multiphoton microscopy (~50 times larger than conventional approaches), and hence the potential of using simply-manufactured devices for scanningless optical sectioning of biological systems
Scientific Productivity of Leading Countries
The main aim of this study is to analyze and compare the scientific productivity of major countries. The related data are collected from Scopus through the open-access portal www.scimagojr.com. Data has been collected on the number of documents and their rank for the top countries. Bibliometric indicators such as Compound Annual Growth Rate (CAGR) and Activity Index (AI) have been used along with a simple percentage. Further, Pearson correlation has been used to compare the rankings. Twenty-four countries have at least 1% of global scientific output in 2018, and all these top countries also ranked in Nature Index 2019 except Indonesia and Malaysia. The top two countries, the United States and China, produced more than 600,000 documents in 2018, with others following distantly. The majority of the top countries are grouped under upper-middle and high income. Fifty percent of the top countries are from Europe. Tremendous improvement in terms of global rank from 1998 to 2018 has been observed for Iran, Indonesia, and Malaysia. All the top countries focus on different disciplines.https://dorl.net/dor/20.1001.1.20088302.2022.20.2.8.
Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24)
MDA-7/IL-24 has noteworthy potential as an anticancer therapeutic because of its diversity of antitumor properties, its lack of toxicity toward normal cells and tissues, and its safety and efficacy as evidenced in a phase I clinical trial. In a recent study, we document that Ad.mda-7-induced ER stress and ceramide production leads to early autophagy that subsequently switches to apoptosis in human prostate cancer cells. During the apoptotic phase, the MDA-7/IL-24 protein physically interacts with Beclin 1 and this interaction might inhibit Beclin 1 function culminating in apoptosis. Conversely, Ad.mda-7 infection leads to calpain-mediated cleavage of the Atg5 protein that might also facilitate a biochemical switch from autophagy to apoptosis. Our recent paper reveals novel aspects of the interplay between autophagy and apoptosis that underlie the cytotoxic action of MDA-7/IL-24 in prostate cancer cells. These new insights into MDA-7/IL-24 action provide intriguing leads for developing innovative combinatorial approaches for prostate cancer therapy
Computational study of heterojunction graphene nanoribbon tunneling transistors with p-d orbital tight-binding method
The graphene nanoribbon (GNR) tunneling field effect transistor (TFET) has been a promising candidate for a future low power logic device due to its sub-60 mV/dec subthreshold characteristic and its superior gate control on the channel electrons due to its one-dimensional nature. Even though many theoretical studies have been carried out, it is not clear that GNR TFETs would outperform conventional silicon metal oxide semiconductor field effect transistors (MOSFETs). With rigorous atomistic simulations using the p/d orbital tight-binding model, this study focuses on the optimization of GNR TFETs by tuning the doping density and the size of GNRs. It is found that the optimized GNR TFET can operate at a half of the supply voltage of silicon nanowire MOSFETs in the ballistic limit. However, a study on the effects of edge roughness on the performance of the optimized GNR TFET structure reveals that experimentally feasible edge roughness can deteriorates the on-current performance if the off-current is normalized with the low power requirement specified in the international technology roadmap for semiconductors. (C) 2014 AIP Publishing LLC
Polyimide-matrix chemical-selective membranes
Preliminary work using polyimide (PI) as the polymer matrix for permselective membranes is reported in this paper. The excellent adhesion of polyimide may be helpful in extending solid-state chemical sensor lifetimes. Electrochemical performance and adhesion to Si3N4 of these membranes is compared to that of conventional PVC-based membranes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28861/1/0000696.pd
Spin wave spectra of single crystal CoPS
The spin waves in single crystals of the layered van der Waals
antiferromagnet CoPS have been measured using inelastic neutron scattering.
The data show four distinct spin wave branches with large ( meV)
energy gaps at the Brillouin zone center indicating significant anisotropy. The
data were modelled using linear spin wave theory derived from a Heisenberg
Hamiltonian. Exchange interactions up to the third nearest-neighbour in the
layered planes were required to fit the data with ferromagnetic
meV between first neighbours, antiferromagnetic meV between third
neighbours, and a very small meV between second neighbours. A
biaxial single-ion anisotropy was required, with a collinear term
meV for the axis parallel to the aligned moment direction and a coplanar term
meV for an axis approximately normal to the layered crystal planes.Comment: 11 pages, 6 figures, 3 table
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