Debris and micrometeorite impact measurements in the laboratory

A method was developed to simulate space debris in the laboratory. This method, which is an outgrowth of research in inertial confinement fusion (ICF), uses laser ablation to accelerate material. Using this method, single 60 micron aluminum spheres were accelerated to 15 km/sec and larger 500 micron aluminum spheres were accelerated to 2 km/sec. Also, many small (less than 10 micron diameter) irregularly shaped particles were accelerated to speeds of 100 km/sec

Measurement of air and nitrogen fluorescence light yields induced by electron beam for UHECR experiments

Most of the Ultra High Energy Cosmic Ray (UHECR) experiments and projects (HiRes, AUGER, TA, EUSO, TUS,...) use air fluorescence to detect and measure extensive air showers (EAS). The precise knowledge of the Fluorescence Light Yield (FLY) is of paramount importance for the reconstruction of UHECR. The MACFLY - Measurement of Air Cherenkov and Fluorescence Light Yield - experiment has been designed to perform such FLY measurements. In this paper we will present the results of FLY in the 290-440 nm wavelength range for dry air and pure nitrogen, both excited by electrons with energy of 1.5 MeV, 20 GeV and 50 GeV. The experiment uses a 90Sr radioactive source for low energy measurement and a CERN SPS electron beam for high energy. We find that the FLY is proportional to the deposited energy (E_d) in the gas and we show that the air fluorescence properties remain constant independently of the electron energy. At the reference point: atmospheric dry air at 1013 hPa and 23C, the ratio FLY/E_d=17.6 photon/MeV with a systematic error of 13.2%.Comment: 19 pages, 8 figures. Accepted for publication in Astroparticle Physic

Wolf-Rayet and LBV Nebulae as the Result of Variable and Non-Spherical Stellar Winds

The physical basis for interpreting observations of nebular morphology around massive stars in terms of the evolution of the central stars is reviewed, and examples are discussed, including NGC 6888, OMC-1, and eta Carinae.Comment: To be published in the Proceedings of IAU Colloquium 169 on Variable and Non-Spherical Stellar Winds in Luminous Hot Stars, ed. B. Wolf (Springer-Verlag, Berlin, Heidelberg). 7 pages, including 5 figures. A full-resolution version of fig 4 is available in the version at http://www.mpia-hd.mpg.de/theory/preprints.html#maclo

Free induction signal from biexcitons and bound excitons

A theory of the free induction signal from biexcitons and bound excitons is presented. The simultaneous existence of the exciton continuum and a bound state is shown to result in a new type of time dependence of the free induction. The optically detected signal increases in time and oscillates with increasing amplitude until damped by radiative or dephasing processes. Radiative decay is anomalously fast and can result in strong picosecond pulses. The expanding area of a coherent exciton polarization (inflating antenna), produced by the exciting pulse, is the underlying physical mechanism. The developed formalism can be applied to different biexciton transients.Comment: RevTeX, 20 p. + 2 ps fig. To appear in Phys. Rev. B1

Differentiating normal and problem gambling: a grounded theory approach.

A previous study (Ricketts &amp; Macaskill, 2003) delineated a theory of problem gambling based on the experiences of treatment seeking male gamblers and allowed predictions to be made regarding the processes that differentiate between normal and problem gamblers. These predictions are the focus of the present study, which also utilised a grounded theory approach, but with a sample of male high frequency normal gamblers. The findings suggest that there are common aspects of gambling associated with arousal and a sense of achievement. The use of gambling to manage negative emotional states differentiated normal and problem gambling. Perceived self-efficacy , emotion management skills and perceived likelihood of winning money back were intervening variables differentiating problem and normal gamblers.</p

Perspectives on Interstellar Dust Inside and Outside of the Heliosphere

Measurements by dust detectors on interplanetary spacecraft appear to indicate a substantial flux of interstellar particles with masses exceeding 10^{-12}gram. The reported abundance of these massive grains cannot be typical of interstellar gas: it is incompatible with both interstellar elemental abundances and the observed extinction properties of the interstellar dust population. We discuss the likelihood that the Solar System is by chance located near an unusual concentration of massive grains and conclude that this is unlikely, unless dynamical processes in the ISM are responsible for such concentrations. Radiation pressure might conceivably drive large grains into "magnetic valleys". If the influx direction of interstellar gas and dust is varying on a ~10 yr timescale, as suggested by some observations, this would have dramatic implications for the small-scale structure of the interstellar medium.Comment: 13 pages. To appear in Space Science Review

The COBE Diffuse Infrared Background Experiment Search for the Cosmic Infrared Background: IV. Cosmological Implications

In this paper we examine the cosmological constraints of the recent DIRBE and FIRAS detection of the extragalactic background light between 125-5000 microns on the metal and star formation histories of the universe.Comment: 38 pages and 9 figures. Accepted for publications in The Astrophysical Journa

Stroma and epithelial interactions in three dimensional cell biology models of ovarian cancer

Over the past years it has become increasingly apparent that the tumour microenvironment plays a crucial role in tumour initiation/development/metastasis. The interactions of the tumour microenvironment and the malignant epithelial cells in epithelial ovarian cancer (EOC) biology remain poorly understood. This is in part due to the lack of representative in vitro models of disease that closely resemble the in vivo situation. A tumour exhibits a three-dimensional (3D) architecture comprising the malignant epithelial cells surrounded by the tumour stroma, which predominately contains the so-called cancer associated fibroblasts (CAFs). In vitro 3D models using primary epithelial cancer cell lines showed striking morphological similarities with the primary tumours. Immunohistochemistry and proteomic profiling further revealed that 3D models more closely resemble the primary tumour compared to traditional 2D culture methods. To further develop these 3D models and to recreate the interactions of epithelial cells with the microenvironment in vitro, heterotypic 3D models were established. Mesenchymal stem cells (MSCs) and immortalized normal ovarian fibroblasts (INOFs) were used to represent the tumour stroma and co-cultured with malignant and non-malignant epithelial ovarian cells. These 3D models proved an improvement to the previously established homotypic 3D models and offered a very good representation of the in vivo tumour. Finally, the recruitment of CAFs into the tumour stroma by EOC cell lines was investigated. Both MSCs and INOFs showed the ability to transdifferentiate into CAFs upon treatment with conditioned medium from an EOC cell line. Transdifferentiation was assessed by the expression of a-smooth muscle actin (aSMA), Vimentin and fibroblast specific protein (FSP). Both differentiated cell lines were also able to induce increased proliferation and invasion rates in a transformed ovarian surface epithelial cell line. These results provide in vitro evidence that both MSCs and INOFs can serve as precursor cell types of CAFs in EOC

Analysis of "Midnight" Tracks in the Stardust Interstellar Dust Collector: Possible Discovery of a Contemporary Interstellar Dust Grain

In January 2006, the Stardust sample return capsule returned to Earth bearing the first solid samples from a primitive solar system body, Comet 81P/Wild2, and a collector dedicated to the capture and return of contemporary interstellar dust. Both collectors were approximately 0.1m(exp 2) in area and were composed of aerogel tiles (85% of the collecting area) and aluminum foils. The Stardust Interstellar Dust Collector (SIDC) was exposed to the interstellar dust stream for a total exposure factor of 20 m(exp 2) day. The Stardust Interstellar Preliminary Examination (ISPE) is a three-year effort to characterize the collection using nondestructive techniques