Systemic Therapy in Endometrial Cancer: Recent Advances.

Endometrial cancer is a chemosensitive disease. Studies have established a clear benefit of chemotherapy in advanced stages and trials are ongoing to define its role in early stages as well. As more molecular pathways are being elucidated there is increasing role for targeted agents and future looks quite promising. We did an extensive search both online and offline for all the relevant articles including chemotherapy and targeted therapy for endometrial cancer

Microwave photovoltage and photoresistance effects in ferromagnetic microstrips

We investigate the dc electric response induced by ferromagnetic resonance in ferromagnetic Permalloy (Ni80Fe20) microstrips. The resulting magnetization precession alters the angle of the magnetization with respect to both dc and rf current. Consequently the time averaged anisotropic magnetoresistance (AMR) changes (photoresistance). At the same time the time-dependent AMR oscillation rectifies a part of the rf current and induces a dc voltage (photovoltage). A phenomenological approach to magnetoresistance is used to describe the distinct characteristics of the photoresistance and photovoltage with a consistent formalism, which is found in excellent agreement with experiments performed on in-plane magnetized ferromagnetic microstrips. Application of the microwave photovoltage effect for rf magnetic field sensing is discussed.Comment: 16 pages, 15 figure

On the line shape of the electrically detected ferromagnetic resonance

This work reviews and examines two particular issues related with the new technique of electrical detection of ferromagnetic resonance (FMR). This powerful technique has been broadly applied for studying magnetization and spin dynamics over the past few years. The first issue is the relation and distinction between different mechanisms that give rise to a photovoltage via FMR in composite magnetic structures, and the second is the proper analysis of the FMR line shape, which remains the "Achilles heel" in interpreting experimental results, especially for either studying the spin pumping effect or quantifying the spin Hall angles via the electrically detected FMR.Comment: 14 pages, 9 figure

A Similarity Based Concordance Approach to Word Sense Disambiguation

This study attempts to solve the problem of Word Sense Disambiguation using a combination of statistical, probabilistic and word matching algorithms. These algorithms consider that words and sentences have some hidden similarities and that the polysemous words in any context should be assigned to a sense after each execution of the algorithm. The algorithm was tested with sufficient sample data and the efficiency of the disambiguation performance has proven to increase significantly after the inclusion of the concordance methodology

A Similarity Based Concordance Approach to Word Sense Disambiguation

This study attempts to solve the problem of Word Sense Disambiguation using a combination of statistical, probabilistic and word matching algorithms. These algorithms consider that words and sentences have some hidden similarities and that the polysemous words in any context should be assigned to a sense after each execution of the algorithm. The algorithm was tested with sufficient sample data and the efficiency of the disambiguation performance has proven to increase significantly after the inclusion of the concordance methodology

The communication of a secondary care diagnosis of autoimmune hepatitis to primary care practitioners: a population-based study

Background Autoimmune Hepatitis is a chronic liver disease which affects young people and can result in liver failure leading to death or transplantation yet there is a lack of information on the incidence and prevalence of this disease and its natural history in the UK. A means of obtaining this information is via the use of clinical databases formed of electronic primary care records. How reliably the diagnosis is coded in such records is however unknown. The aim of this study therefore was to assess the proportion of consultant hepatologist diagnoses of Autoimmune Hepatitis which were accurately recorded in General Practice computerised records. Methods Our study population were patients with Autoimmune Hepatitis diagnosed by consultant hepatologists in the Queens Medical Centre, Nottingham University Hospitals (UK) between 2004 and 2009. We wrote to the general practitioners of these patients to obtain the percentage of patients who had a valid READ code specific for Autoimmune Hepatitis. Results We examined the electronic records of 51 patients who had biopsy evidence and a possible diagnosis of Autoimmune Hepatitis. Forty two of these patients had a confirmed clinical diagnosis of Autoimmune Hepatitis by a consultant hepatologist: we contacted the General Practitioners of these patients obtaining a response rate of 90.5% (39/42 GPs). 37/39 of these GPs responded with coding information and 89% of these patients (33/37) used Read code J638.00 (Autoimmune Hepatitis) to record a diagnosis. Conclusions The diagnosis of Autoimmune Hepatitis made by a Consultant Hepatologist is accurately communicated to and electronically recorded by primary care in the UK. As a large proportion of cases of Autoimmune Hepatitis are recorded in primary care, this minimises the risk of introducing selection bias and therefore selecting cases using these data will be a valid method of conducting population based studies on Autoimmune Hepatitis

Crystal structure and ionic conductivity of a new bismuth tungstate, Bi<SUB>3</SUB>W<SUB>2</SUB>O<SUB>10.5</SUB>

The compound Bi3W2O10.5 was synthesized by the solid-state technique from Bi2O3 and WO3 in stoichiometric quantities. Single crystals were grown by the melt-cooling technique and the crystal structure was solved in the tetragonalI4/m space group with a = 3.839 (1) &#197;,c = 16.382 (5) &#197;,V = 241.4 (1) &#197;3,Z = 4 and was refined to anR index of 0.0672. The structure represents a modification of the Aurivillius phase and consists of [Bi2O2]2+ units separated by WO8 polyhedra. a.c. impedance studies indicate oxide ion conductivity of 2.91 10-5 Scm-1 at 600&#176;C

BIOCHEMICAL ANALYSIS OF AN ENDEMIC FRESHWATER CRAB, SARTORIANA SPINIGERA (WOOD-MASON, 1871) FROM EAST COAST OF INDIA

In the present investigation an attempt has been made to know the biochemical composition of freshwater crab meat of Sartoriana spinigera (Wood-Mason, 1871) before and after their spawning seasons during the months of January to March and July to September. The protein content of meat of female crabs varied from 30.03% to 59.29%, lipid 7.01% to 11.29% and ash between 38.75 and 39.44% dry weight, whereas the moisture ranged between 71.26% and 79.51%. The protein, lipid and ash contents were recorded highest during the month of January to March whereas, lowest percentages of these were observed during July to September. The biochemical composition of crab meat having high protein justifies the edible quality of these crabs by humans