3,587 research outputs found
An integrated core competence evaluation framework for portfolio management in the oil industry
The proponents of resource-based theory argue that efficient management of core competence portfolio provides sustainable competitive advantages. However, literature demonstrates little evidence regarding (i) how to identify core competence, specifically for a company operating in the oil sector, (ii) how to identify tangible and intangible resources related to the core competence of the company, and (iii) how to manage a company’s competence portfolio more efficiently by forging network alliances with collaborating firms. Drawing upon resource-based theory this paper presents a core competence evaluation framework for managing the competence portfolio of an oil company. The paper introduces a network typology to illustrate how to form different types of strategic alliance relations with partnering firms to manage and grow the competence portfolio. The framework is tested using a case study approach involving face-to-face structured interviews with twenty-five divisional managers of a large oil company in the Middle East. We identified purchasing, refining and sales and marketing as strong candidates to be the core competencies of the company. However, despite the company’s core business of refining oil, the core competencies were identified to be their research and development and performance management (PM) capabilities. We further provide a procedure to determine different kinds of physical, intellectual and cultural resources making a dominant impact on company’s competence portfolio. In addition, we provide a comprehensive set of guidelines on how to develop core competence further by forging a partnership alliance choosing an appropriate network topology. The paper makes many contributions to the field of strategic management and core competence evaluation in the oil sector. The guidelines provided can assist practitioners with devising appropriate network relationships with partnering companies in order to outsource, divest, protect and/or develop their core competence portfolio
Evaluation of Heavy Metal Concentration in Drinking Water Collected from Local Wells and Boreholes of Dutse Town, North West, Nigeria
Water samples collected from Dutse Town, Jigawa State, were studied and analyzed for heavy metals. A total of 48 samples were collected from 24 different sampling sites in Dutse town namely: FUD, Gidan Dubu Yadi, Bakwato 1, Bakwato 2, Tashar Danwake, Fatara, Kargo, Garu/Emir palace, Fagoji 1, Fagoji 2, Zai, Jigawa Sarki, Kachi, Limawa, Galamawa, Dasina, Takur Adua, Jigawar Tsada, Takur Site, Dan Masara, Mopol Base, G-9 Site and Aminu Kano Way/Cikin Gari. The samples were studied and analyzed for eight (8) heavy metals namely; Cadmium (Cd), Cobalt (Co), Copper (Cu), Iron (Fe), Manganese (Mn), Lead (Pb), Mercury (Hg) and Nickel (Ni). The results obtained were compared with the international standards. The samples were analyzed at the Central Laboratory, Ahmadu Bello University, Zaria. Atomic Absorption Spectrometer (AAS) was used in this study and the average concentration of these heavy metals are 0.0034, 0.0409, 0.0151, 1.8241, 0.01471, 0.2731, 2.2829 and 0.0433 mg/l for Cd, Co, Cu, Fe, Pb, Mn, Hg and Ni respectively. Among the analyzed heavy metals, Cd, Co, Cu and Ni were below the recommended level set by United State Environmental Protection Agency (USEPA) and World Health Organization (WHO) while Fe, Pb, Mn and Hg were higher than the recommended level set by USEPA and WHO for safe drinking water. This imply that the water collected from these sampling areas were contaminated with heavy metals which may have serious health hazard to the people using such water for drinking and other domestic activities. Keywords: Heavy metals, Wells, Boreholes, Drinking Water, Dutse Tow
Immune thrombocytopenic purpura in a 5-month-old female with rotavirus infection
No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65028/1/22368_ftp.pd
The role of place branding and image in the development of sectoral clusters: the case of Dubai
This paper contextualizes how place branding and image influence the development of Dubai’s key sectoral clusters, including the key determinants of growth and success under the impression of Porter’s cluster theory. The approach is exploratory and of a qualitative inductive nature. Data was collected through conducting 21 semi-structured interviews with Dubai’s marketing/communication managers and stakeholders. Findings suggest that Dubai’s traditional clusters, namely, trading, tourism and logistics that have strong place branding and image show strong signs of success owing to Dubai’s geographical location (i.e., physical conditions). Among the new clusters, the financial sector is also benefitting from place branding. The results suggest that the success of traditional clusters have a positive spill over effect on the new clusters, in particular on construction and real estate. For policy makers it is worth to note that the recent success of the financial services cluster in Dubai will have positive impact on both, the traditional as well new clusters. The marketing and brand communication managers must consider the correlation and interplay of strength of activities amongst trading, tourism and logistics clusters and its implication while undertaking place branding for clients in their sector
How do entrepreneurs learn and engage in an online community-of-practice? A case study approach
This paper investigates the ways in which entrepreneurs use communities of practice (CoPs) to express themselves, using narrative theory and rhetorical analysis, to gain insight into an electronic social network medium, namely, YoungEntrepreneur.com. In particular, the study focuses on CoPs themes, including why entrepreneurs engage in CoPs, what role the moderators and resident entrepreneurs can play in managing online CoPs, on communication rituals of the knowledge sharing through interactivity, and on “how to develop an intervention” to maintain and stimulate entrepreneurs for engaging in on-line community. Findings reveal that topic title plays major role in attracting people. Successful topics with successful conclusion (in terms of the original query was answered) will not necessary get high responses and vice versa. It is observed that the domain expert does not play a big role in keeping the discussion going. Finally, the study also discovered that entrepreneurs like to communicate in story telling genre. A comprehensive set of engagement measurement tools are introduced to effectively measure the engagement in a virtual CoP, along with a classification to define and categorise discourse of messages in terms of content and context, which allow practitioners to understand the effectiveness of a social networking site
Knowledge sharing by entrepreneurs in a virtual community of practice (VCoP)
Purpose. This paper examines how entrepreneurs engage in a Virtual Community of Practice (VCoP) to share knowledge. Intensity of engagement is taken as a proxy to measure the strength of knowledge sharing.
Design/methodology/approach. The archival data spanning over a three-year period from ‘Start-up-Nation©’ (a VCoP purposefully setup for entrepreneurs) is used for analysis. A set of indices are introduced to measure participants’ intensity of engagement in terms of message length, message frequency and reciprocity in the knowledge sharing process. Content analysis is employed to test a sample of ‘highly engaged’, ‘moderately engaged’, ‘low engaged’ and ‘not engaged’ discussion topics as part of the on-line discourse.
Findings. We find that entrepreneurs normally use short (fewer than 100 words) or medium (fewer than 250 words) message size to contribute to the discussions. In addition, we find that senior members and discussion moderators play important roles in igniting the ‘reciprocity’ behaviour in stimulating the interest of the community with the topic discussion. We also find that highly engaged topics usually lead to further discussion threads.
Originality/value. This is the first study of its kind to explore how entrepreneurs engage in a VCoP to share their knowledge and experiences. The set of measurement indices tested here provide a tool for the owner, designer and moderator of the VCoP to measure the utility of their website in terms of its members’ participation. In addition, the set of textual and subjective interventions identified here enable the moderator (administrator) of a VCoP to design effective interventions to facilitate on-line discourse and augment the knowledge sharing process amongst its community members
Sources of Community Health Worker Motivation: A Qualitative Study in Morogoro Region, Tanzania.
There is a renewed interest in community health workers (CHWs) in Tanzania, but also a concern that low motivation of CHWs may decrease the benefits of investments in CHW programs. This study aimed to explore sources of CHW motivation to inform programs in Tanzania and similar contexts. We conducted semi-structured interviews with 20 CHWs in Morogoro Region, Tanzania. Interviews were digitally recorded, transcribed, and coded prior to translation and thematic analysis. The authors then conducted a literature review on CHW motivation and a framework that aligned with our findings was modified to guide the presentation of results. Sources of CHW motivation were identified at the individual, family, community, and organizational levels. At the individual level, CHWs are predisposed to volunteer work and apply knowledge gained to their own problems and those of their families and communities. Families and communities supplement other sources of motivation by providing moral, financial, and material support, including service fees, supplies, money for transportation, and help with farm work and CHW tasks. Resistance to CHW work exhibited by families and community members is limited. The organizational level (the government and its development partners) provides motivation in the form of stipends, potential employment, materials, training, and supervision, but inadequate remuneration and supplies discourage CHWs. Supervision can also be dis-incentivizing if perceived as a sign of poor performance. Tanzanian CHWs who work despite not receiving a salary have an intrinsic desire to volunteer, and their motivation often derives from support received from their families when other sources of motivation are insufficient. Policy-makers and program managers should consider the burden that a lack of remuneration imposes on the families of CHWs. In addition, CHWs' intrinsic desire to volunteer does not preclude a desire for external rewards. Rather, adequate and formal financial incentives and in-kind alternatives would allow already-motivated CHWs to increase their commitment to their work
Speed breeding in growth chambers and glasshouses for crop breeding and model plant research
‘Speed breeding’ (SB) shortens the breeding cycle and accelerates crop research through rapid generation advancement. SB can be carried out in numerous ways, one of which involves extending the duration of plants’ daily exposure to light, combined with early seed harvest, to cycle quickly from seed to seed, thereby reducing the generation times for some long-day (LD) or day-neutral crops. In this protocol, we present glasshouse and growth chamber–based SB approaches with supporting data from experimentation with several crops. We describe the conditions that promote the rapid growth of bread wheat, durum wheat, barley, oat, various Brassica species, chickpea, pea, grass pea, quinoa and Brachypodium distachyon. Points of flexibility within the protocols are highlighted, including how plant density can be increased to efficiently scale up plant numbers for single-seed descent (SSD). In addition, instructions are provided on how to perform SB on a small scale in a benchtop growth cabinet, enabling optimization of parameters at a low cost
Absence of miR-146a in podocytes increases risk of diabetic glomerulopathy via upregulation of erbb4 and notch-1
Podocyte injury is an early event in diabetic kidney disease and is a hallmark of glomerulopathy. MicroRNA-146a (miR-146a) is highly expressed in many cell types under homeostatic conditions, and plays an important anti-inflammatory role in myeloid cells. However, its role in podocytes is unclear. Here, we show that miR-146a expression levels decrease in the glomeruli of patients with type 2 diabetes (T2D), which correlates with increased albuminuria and glomerular damage. MiR-146a levels are also significantly reduced in the glomeruli of albuminuric BTBR ob/ob mice, indicating its significant role in maintaining podocyte health. miR-146a-deficient mice (miR-146a-/-) showed accelerated development of glomerulopathy and albuminuria upon streptozotocin (STZ)-induced hyperglycemia. The miR-146a targets, Notch-1 and ErbB4, were also significantly upregulated in the glomeruli of diabetic patients and mice, suggesting induction of the downstream TGFβ-signaling. Treatment with a pan-ErbB kinase inhibitor erlotinib with nanomolar activity against ErbB4 significantly suppressed diabetic glomerular injury and albuminuria in both WT and miR-146a-/- animals. Treatment of podocytes in vitro with TGF-β1 resulted in increased expression of Notch-1, ErbB4, pErbB4 and pEGFR, the heterodimerization partner of ErbB4, suggesting increased ErbB4/EGFR signaling. TGF-β1 also increased levels of inflammatory cytokine MCP-1 and MCP-1 induced protein-1 (MCPIP1), a suppressor of miR-146a, suggesting an autocrine loop. Inhibition of ErbB4/EGFR with erlotinib co-treatment of podocytes suppressed this signaling. Our findings suggest a novel role for miR-146a in protecting against diabetic glomerulopathy and podocyte injury. They also point to Erbb4/EGFR as a novel, druggable target for therapeutic intervention, especially since several pan-ErbB inhibitors are clinically available
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