The anticancer agent prodigiosin is not a multidrug resistance protein substrate

The brilliant red pigments prodiginines are natural secondary metabolites that are produced by select species of Gram-negative and Gram-positive bacteria. These molecules have received significant attention due to their reported antibacterial, antifungal, immunosuppressive, and anticancer activities. In this study, a Serratia marcescens SER1 strain was isolated and verified using 16s rDNA. The prodigiosin was purified using silica chromatography and was analyzed by 1H-NMR spectroscopy. The cell cytotoxic effects of

Kontribusi Sektor Perikanan dalam Peningkatan Perekonomian Provinsi Riau

Provinsi Riau .memiliki keunggulan komparatif karena letaknya yang strategis. Pertama, Riau dekatdengan negara-negara ASEAN, terutama Singapore, Malaysia dan Thailand. Kedua, Riau terletak dirute perdagangan dan pelayaran internasional di Asia-Pacifik. Ketiga, lokasi Riau dekat denganSingapore yang merupakan salah satu pusat perdagangan dunia. Keempat, Riau terletak di tengah PulauSumatera, dilewati lintas Barat dan lintas Timur

Strategic Communication Museum Kereta Api Ambarawa sebagai Project Manager

Tugas akhir berupa karya bidang ini dilatarbelakangi oleh sangat potensialnyamuseum kereta api Ambarawa sebagai rancangan museum kereta apiInternasional, akan tetapi kurangnya promosi museum membuat museum jarangdikenal oleh masyarakat dan belum banyak dikunjungi. Terbukti dari riset yangtelah dilaksanakan, diperoleh angka brand knowledge informan terhadap museumKA sebesar 58% yang menunjukan bahwa orang belum tahu museum kereta apiAmbarawa, dimana letaknya dan apa saja barang yang dikoleksi disana.Sedangkan tingkat afeksi menunjukan angka 37%, hal ini menunjukan bahwaorang masih belum mau mencari tahu informasi tentang museum KA Ambarawaitu sendiri. Sedangkan hal behavior berupa tingkat kunjungan masihlah berada dirata-rata kunjungan sebesar 600 orang per hari.Tujuan dari diadakannya Strategic Communication Museum Kereta ApiAmbarawa ini adalah mempromosikan Museum Kereta Api Ambarawa gunameningkatkan pengetahuan dan sikap masyarakat untuk berkunjung ke museumKereta Ambarawa. Selain itu karya bidang ini juga bertujuan untuk meningkatkanafeksi, kognisi dan juga behavior pengunjung maupun calon pengunjung museumkereta api Ambarawa.Pada 1 bulan pelaksanaan di bulan Mei 2015, kegiatan berhasil mendapatkanpeningkatan pengunjung yang signifikan di bulan Mei dengan total kunjungan21.514 orang (dewasa) dan 9.272 orang (anak-anak). Rata-rata di bulan Meimenunjukan angka 993 orang per hari. Jika dikatergorikan berdasarkan kunjunganweekend dan weekdays, pada weekdays menunjukan angka rata-rata 623 orang danpada weekend menunjukan angka rata-rata 1.769 orang. Aspek kognisitentangpengetahuan pengunjung tentang museum Kereta Api Ambarawa tentang apa,dimana letak museum, koleksi, dan juga potensi museum kereta api Ambarawadalam pelaksanaannya meningkatkhingga presentase 73% dari angka 58%.Dalamaspek afeksi didasarkan pada minat masyarakat untuk mau berkunjung keMuseum Kereta Api Ambarawa dalam pelaksanaannya meningkat dia angka 66%dari 37%.Karya bidang ini menunjukkan bahwa “Strategic CommunicationMuseum Kereta Api ambarawa ‘Sepoorheroes' berhasil dilakukan sesuai goalsyang ditentukan

Pengaruh Pengalaman Praktik Kerja Industri dan Locus Of Control terhadap Kesiapan Kerja Siswa Kelas XII Smk Negeri 1 Surakarta

: The purpose of this research are to verify and to analyze: 1) the influence of industrial practical work experience for job readiness of students of SMK NEGERI 1 Surakarta year 2012/2013, 2) The influence of locus of control for job readiness of students of SMK Negeri 1 Surakarta year 2012/2013, and 3) The influence of industrial practical work experience and locus of control for job readiness of students of SMK Negeri 1 Surakarta year 2012/2013. This research is descriptive quantitative research with hypothesis testing. This research is located in SMK Negeri 1 Surakarta. The populations of this research were students of XII classes which are 299 students. The samplestaken were 80 students using proportional random sampling technique. The data collection techniques were questionnaire and documentation method. The validations of data were using validity and reliability testing. The data analysis techniques used to test the hypothesis were correlation and multiple regression analysis. The result of this research indicate that the first and second hypothesis test yield Ho was rejected and Ha was accepted because the value of rcalculation for X1 =0.538 and X2 = 0.270 is larger than rtable = 0,220.whereas, the third hypothesis test was using regression analysis with two predictor obtain the value of correlation coefficient R2 equal to 0.31 or 31% with regression equation Ŷ = 13,094 + 0,572X1 + 0,459X2. For the value of f calculation = 17,364 > ftable = 3.44 at the 5% of significant level. The amount of the relative contribution and effective contribution to X1 toward Y equal to 86,88% and 27%, while X2 toward Y equal to 13,12% and 4,06%. The conclusions of this research are: 1) there is a significant effect of industrial practical work experience for job readiness of students of SMK NEGERI 1 Surakarta year 2012/2013, 2) there is a significant effect of locus of control for job readiness of students of SMK NEGERI 1 Surakarta year 2012/2013, and 3) there is a significant effect of industrial practical work experience and locus of control for job readiness of students of SMK Negeri 1 Surakarta year 2012/2013

Nonlinear photonics properties of porphyrins nanocomposites and self-assembled porphyrins

Two major reasons limit porphyrins photonic applications: (i) the difficulty of handling them in liquid solutions and (ii) their degradation with long exposure to light. This necessitates the use of appropriate solid matrices to host the porphyrin compounds such as Nafion (117), a stable and inert ion exchange polymer. The first part of this publication confirms such a possibility. In addition to their effective NLO properties, an enhancement of the Soret and Q-bands absorbance width have been observed by blending three different porphyrin molecules in the Nafion column matrix membrane. This is an important development towards achieving efficient photon-harvesting medium for possible application in photonic devices. The second part of this contribution reports on the self-assembly/molecular recognition of a specific class of porphyrins giving rise to tubular nano-systems with potential THG nonlinear properties

The Hilbert basis method for D-flat directions and the superpotential

We discuss, using the Hilbert basis method, how to efficiently construct a complete basis for D-flat directions in supersymmetric Abelian and non-Abelian gauge theories. We extend the method to discrete (R and non-R) symmetries. This facilitates the construction of a basis of all superpotential terms in a theory with given symmetries.Comment: 11 pages; a related mathematica code can be found at http://einrichtungen.ph.tum.de/T30e/codes/NonAbelianHilbert

Topological Orbifold Models and Quantum Cohomology Rings

We discuss the toplogical sigma model on an orbifold target space. We describe the moduli space of classical minima for computing correlation functions involving twisted operators, and show, through a detailed computation of an orbifold of ${\bf CP}^1$ by the dihedral group $D_{4},$ how to compute the complete ring of observables. Through this procedure, we compute all the rings from dihedral ${\bf CP}^1$ orbifolds; we note a similarity with rings derived from perturbed $D-$series superpotentials of the $A-D-E$ classification of $N = 2$ minimal models. We then consider ${\bf CP}^2/D_4,$ and show how the techniques of topological-anti-topological fusion might be used to compute twist field correlation functions for nonabelian orbifolds.Comment: 48 pages, harvmac, HUTP-92/A06