8,960 research outputs found

    The effect of demographic changes on saving for life cycle motives in developing countries

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    If developing countries follow the same paths that industrialized countries have followed, saving for retirement will initially become more important as the population growth rate declines. To calculate the potential importance of life-cycle savings (saving for retirement), the paper presents a simulation model that translates demographic projections into savings-rate projections. It simulated aggregate rates for life-cycle savings for Brazil, China, Korea, Mexico, Nigeria, Pakistan and Turkey. The savings rates increase 5 or 6 percentage points when the last baby boomers enter the work force and begin to save after their children leave home. The effect on life-cycle savings is dramatic; the effect on total savings rates which are often three or four times as high, is not. Simulated life-cycle savings rates peak at an absolute 10 percent or less in all cases. The patterns of these projections seem robust with regard to assumptions about productivity growth, interest rates, and age-specific participation in the labor force.Banks&Banking Reform,Environmental Economics&Policies,Economic Theory&Research,Health Monitoring&Evaluation,Inequality

    Glass Ceiling Commission - The Impact of the Glass Ceiling and Structural Change on Minorities and Women

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    Glass Ceiling ReportGlassCeilingBackground12StructuralChange.pdf: 9391 downloads, before Oct. 1, 2020

    Borrowing, resource transfers, and external shocks to developing countries : historical and counterfactual

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    Since the late 1970's the buildup and servicing of external debt has dominated the economic situation in many developing countries. This paper gathers some statistical evidence on the magnitude of lending and repayment and on the question of whether repayment reduces the resources available for development. The evidence largely confirms commonly held beliefs. Although most debtor countries have made net transfers of resources to creditors, middle-income countries that have not had to reschedule their debts have averaged smaller net transfers than those that did reschedule. Adverse changes in terms of trade since 1978 accounted for most of the debt buildup in many non-oil developing countries. The mostly favorable terms of trade for oil exporters, on the other hand, gave them large gains that could have more than covered the losses of the oil importing developing countries. Heavy borrowing by oil exporters during favorable times seems to have been a major factor in precipitating the debt crisis. Since the debt crisis, the highly indebted countries have greatly increased their official borrowing. Increased official lending might help the resource balance and domestic investment of lower-income countries more than those of middle-income countries with high commercial debts.Environmental Economics&Policies,Economic Theory&Research,Banks&Banking Reform,Strategic Debt Management,Financial Intermediation

    Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I.

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    In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection. Among these, the tetraspanin CD81 and scavenger receptor B type I (SR-BI), both of which localize to specialized plasma membrane domains enriched in cholesterol, have been suggested to be key players in HCV entry. In the current study, we used a recently developed in vitro HCV infection system to demonstrate that both CD81 and SR-BI are required for authentic HCV infection in vitro, that they function cooperatively to initiate HCV infection, and that CD81-mediated HCV entry is, in part, dependent on membrane cholesterol

    Myxococcus xanthus gliding motors are elastically coupled to the substrate as predicted by the focal adhesion model of gliding motility

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    Myxococcus xanthus is a model organism for studying bacterial social behaviors due to its ability to form complex multi-cellular structures. Knowledge of M. xanthus surface gliding motility and the mechanisms that coordinate it are critically important to our understanding of collective cell behaviors. Although the mechanism of gliding motility is still under investigation, recent experiments suggest that there are two possible mechanisms underlying force production for cell motility: the focal adhesion mechanism and the helical rotor mechanism which differ in the biophysics of the cell-substrate interactions. Whereas the focal adhesion model predicts an elastic coupling, the helical rotor model predicts a viscous coupling. Using a combination of computational modeling, imaging, and force microscopy, we find evidence for elastic coupling in support of the focal adhesion model. Using a biophysical model of the M. xanthus cell, we investigated how the mechanical interactions between cells are affected by interactions with the substrate. Comparison of modeling results with experimental data for cell-cell collision events pointed to a strong, elastic attachment between the cell and substrate. These results are robust to variations in the mechanical and geometrical parameters of the model. We then directly measured the motor-substrate coupling by monitoring the motion of optically trapped beads and find that motor velocity decreases exponentially with opposing load. At high loads, motor velocity approaches zero velocity asymptotically and motors remain bound to beads indicating a strong, elastic attachment

    Anisotropic magnetoresistance in antiferromagnetic Sr2IrO4

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    We report point-contact measurements of anisotropic magnetoresistance (AMR) in a single crystal of antiferromagnetic (AFM) Mott insulator Sr2IrO4. The point-contact technique is used here as a local probe of magnetotransport properties on the nanoscale. The measurements at liquid nitrogen temperature revealed negative magnetoresistances (MRs) (up to 28%) for modest magnetic fields (250 mT) applied within the IrO2 a-b plane and electric currents flowing perpendicular to the plane. The angular dependence of MR shows a crossover from four-fold to two-fold symmetry in response to an increasing magnetic field with angular variations in resistance from 1-14%. We tentatively attribute the four-fold symmetry to the crystalline component of AMR and the field-induced transition to the effects of applied field on the canting of AFM-coupled moments in Sr2IrO4. The observed AMR is very large compared to the crystalline AMRs in 3d transition metal alloys/oxides (0.1-0.5%) and can be associated with the large spin-orbit interactions in this 5d oxide while the transition provides evidence of correlations between electronic transport, magnetic order and orbital states. The finding of this work opens an entirely new avenue to not only gain a new insight into physics associated with spin-orbit coupling but also better harness the power of spintronics in a more technically favorable fashion.Comment: 13 pages, 3 figure
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