Spatially resolved ultrafast precessional magnetization reversal

Spatially resolved measurements of quasi-ballistic precessional magnetic switching in a microstructure are presented. Crossing current wires allow detailed study of the precessional switching induced by coincident longitudinal and transverse magnetic field pulses. Though the response is initially spatially uniform, dephasing occurs leading to nonuniformity and transient demagnetization. This nonuniformity comes in spite of a novel method for suppression of end domains in remanence. The results have implications for the reliability of ballistic precessional switching in magnetic devices.Comment: 17 pages (including 4 figures), submitted to Phys. Rev. Let

Prevention of anxiety among at-risk children: a systematic review and meta-analysis

Background Anxiety disorders are common, often start in childhood and run a chronic course. As such there is a need for effective prevention. Methods We conducted a systematic review and meta-analyses of randomized, controlled trials to prevent the onset of anxiety disorders in ‘at risk’ young people. Diagnostic and symptom outcomes were examined. Putative moderators were tested as was publication bias. Results We included 16 trials (2545 young people). Two trials reported diagnostic outcomes, and significant effects were found for these at end-of-programme (RR = .09, 95%CI = .02 to .16), 6- (RR = .17, 95%CI = .06 to .27) and 12-month (RR = .31, 95%CI .17 to .45) follow-ups. Based on 16 trials, improved anxiety symptoms were significant compared to nonattention controls only, with small effect sizes reported by young people at the end-of-programmes, 6- and 12-month follow-ups; and by parents at the end of the programmes and 12-, but not 6-, month follow-ups. There was no evidence of significant moderation or publication bias. Conclusions Fourteen studies included children and young people who presented with elevated anxiety symptoms, but anxiety disorder was not ruled out in the participants in these studies. Hence, these studies might be reporting results of mixed prevention/early intervention programmes. Prevention programmes that target developmental risk factors, not only disorder maintaining factors, appear most promising. The clinically meaningful impact of anxiety disorder prevention programmes remains unknown

Fitness Correlates Of Song Repertoire Size In Free-Living Song Sparrows (Melospiza Melodia)

Models of sexual selection propose that exaggerated secondary sexual ornaments indicate a male\u27s own fitness and the fitness of his offspring. These hypotheses have rarely been thoroughly tested in free-living individuals because overall fitness, as opposed to fitness components, is difficult to measure. We used 20 years of data from song sparrows ( Melospiza melodia) inhabiting Mandarte Island, British Columbia, Canada, to test whether a male\u27s song repertoire size, a secondary sexual trait, predicted overall measures of male or offspring fitness. Males with larger song repertoires contributed more independent and recruited offspring, and independent and recruited grandoffspring, to Mandarte\u27s population. This was because these males lived longer and reared a greater proportion of hatched chicks to independence from parental care, not because females mated to males with larger repertoires laid or hatched more eggs. Furthermore, independent offspring of males with larger repertoires were more likely to recruit and then to leave more grandoffspring than were offspring of males with small repertoires. Although we cannot distinguish whether observed fitness variation reflected genetic or environmental effects on males or their offspring, these data suggest that female song sparrows would gain immediate and intergenerational fitness benefits by pairing with males with large song repertoires

Conceptual learning : the priority for higher education

The common sense notion of learning as the all-pervasive acquisition of new behaviour and knowledge, made vivid by experience, is an incomplete characterisation, because it assumes that the learning of behaviour and the learning of knowledge are indistinguishable, and that acquisition constitutes learning without reference to transfer. A psychological level of analysis is used to argue that conceptual learning should have priority in higher education

Imaging the dephasing of spin wave modes in a square thin film magnetic element

Copyright © 2004 The American Physical SocietyWe have used time-resolved scanning Kerr effect microscopy to study dephasing of spin wave modes in a square Ni81Fe19 element of 10 μm width and 150 nm thickness. When a static magnetic field H was applied parallel to an edge of the square, demagnetized regions appeared at the edges orthogonal to the field. When H was applied along a diagonal, a demagnetized region appeared along the opposite diagonal. Time-resolved images of the out-of-plane magnetization component showed stripes that lie perpendicular to H and indicate the presence of spin wave modes with wave vector parallel to the static magnetization. The transient Kerr rotation was measured at different positions along an axis parallel to H, and the power spectra revealed a number of different modes. Micromagnetic simulations reproduce both the observed images and the mode frequencies. This study allows us to understand an anisotropic damping observed at the center of the square element in terms of dephasing of the resonant mode spectrum

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.

White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational modifications of histones have been shown to regulate cellular energy metabolism, but their role in white adipose tissue physiology remains incompletely understood. Here we show that histone deacetylase 3 (HDAC3) regulates WAT metabolism and function. Selective ablation of Hdac3 in fat switches the metabolic signature of WAT by activating a futile cycle of de novo fatty acid synthesis and β-oxidation that potentiates WAT oxidative capacity and ultimately supports browning. Specific ablation of Hdac3 in adipose tissue increases acetylation of enhancers in Pparg and Ucp1 genes, and of putative regulatory regions of the Ppara gene. Our results unveil HDAC3 as a regulator of WAT physiology, which acts as a molecular brake that inhibits fatty acid metabolism and WAT browning.Histone deacetylases, such as HDAC3, have been shown to alter cellular metabolism in various tissues. Here the authors show that HDAC3 regulates WAT metabolism by activating a futile cycle of fatty acid synthesis and oxidation, which supports WAT browning

Estimation of Sounding Uncertainty from Measurements of Water Mass Variability

Analysis techniques are introduced that allow for estimation of potential sounding uncertainty due to water mass variability from reconnaissance campaigns in which oceanographic parameters are measured at a high temporal and spatial resolution. The analysis techniques do not require sounding data, thus analyses can be tailored to match any survey system; this allows for pre-analysis campaigns to optimize survey instrumentation and sound speed profiling rates such that a desired survey specification can be maintained. Additionally, the output of the analysis methods can potentially provide a higher fidelity estimation of sounding uncertainty due to water mass variability than uncertainty models in common use.Se presentan análisis técnicos que permiten una estimación de posibles incertidumbres en los sondeos, debidas a la variabilidad de la masa de agua, procedentes de campañas de reconocimiento en las que los parámetros oceanográficos son medidos con una resolución temporal y espacial elevada. Los análisis técnicos no requieren los datos de sondeos, así pues dichos análisis pueden adaptarse a cualquier sistema hidrográfico. Esto permite campañas de análisis previos para optimizar la instrumentación hidrográfica y los niveles de descripción de la velocidad del sonido, para que pueda mantenerse una especificación hidrográfica deseada. Además, el resultado de los métodos analíticos puede proporcionar potencialmente una estimación de la fidelidad de las incertidumbres en los sondeos, debidas a una variabilidad de la masa de agua mayor que la de los modelos de incertidumbres que se utilizan corrientemente.Des techniques d’analyse sont introduites afin de permettre l’estimation de l’incertitude potentielle des sondes due à la variabilité de la masse d’eau à partir de campagnes de reconnaissance dans lesquelles les paramètres océanographiques sont mesurés avec une haute résolution temporelle et spatiale. Les techniques d’analyse ne nécessitant pas de données de sondes, les analyses peuvent donc être ajustées pour s’adapter à tout système de levés ; ceci permet aux campagnes de pré-analyse d’optimiser l’instrumentation hydrographique ainsi que les niveaux de profilage de la vitesse du son de manière à conserver une spécification de levé souhaitée. En outre, le résultat des méthodes d’analyse peut potentiellement fournir une estimation à plus haute fidélité, en ce qui concerne les incertitudes des sondes du fait de la variabilité de la masse d’eau, que les modèles d’incertitude en usage

Vegetation Patterns in and among Pannes (Calcareous Intradunal Ponds) at the Indiana Dunes National Lakeshore, Indiana

The relationships between plant species composition and dispersion, water chemistry and water depth/depth to water table were studied in five calcareous intradunal ponds (pannes) bordering the southern tip of Lake Michigan. The panne systems contained eight plant species threatened and endangered in Indiana. The aquatic zone was dominated by Chara, the pond edge by Rhynchospora capillacea, Juncus balticus and Utricularia cornuta, and the area surrounding the pond by Hypericum kalmianum. The water chemistry was typical of hardwater ponds in the area, probably affecting species composition but not species dispersion within the pannes. A significant correlation between the first axis scores from a reciprocal-averaging ordination and water depth/depth to water was demonstrated. Panne species are fitted to a model based on hydrology proposed by van der Laan for dune-slack vegetation in the Netherlands.SUNY BrockportEnvironmental Science and Ecology Faculty Publication

Unraveling the Shift to the Entrepreneurial Economy

A recent literature has emerged providing compelling evidence that a major shift in the organization of the developed economies has been taking place: away from what has been characterized as the managed economy towards the entrepreneurial economy. In particular, the empirical evidence provides consistent support that (1) the role of entrepreneurship has significantly increased, and (2) a positive relationship exists between entrepreneurial activity and economic performance. However, the factors underlying this observed shift have not been identified in a systematic manner. The purpose of this paper is to suggest some of the factors leading to this shift and implications for public policy. In particular, we find that a fundamental catalyst underlying the shift from the managed to the entrepreneurial economy involved the role of technological change. However, we also find that it was not just technological change but rather involved a number of supporting factors, ranging from the demise of the communist system, increased globalization, new competition for multinational firms and higher levels of prosperity. Recognition of the causes of the shift from the managed to the entrepreneurial economy suggests a rethinking of the public policy approach. Rather than the focus of directly and exclusively on promoting startups and SMEs, it may be that the current approach to entrepreneurship policy is misguided. The priority should not be on entrepreneurship policy but rather a more pervasive and encompassing approach, policy consistent with an entrepreneurial economy