466 research outputs found
A comprehensive analysis of the (R13xR13)R13.9{\deg} type II structure of silicene on Ag(111)
In this paper, using the same geometrical approach than for the (2R3x2R3)
R30{\deg} structure (H. Jamgotchian et al., 2015, Journal of Physics. Condensed
Matter 27 395002), for the (R13xR13)R13.9{\deg} type II structure, we propose
an atomic model of the silicene layer based on a periodic relaxation of the
strain epitaxy. This relaxation creates periodic arrangements of perfect areas
of (R13xR13)R13.9{\deg} type II structure surrounded by defect areas. A
detailed analysis of the main published experimental results, obtained by
Scanning Tunneling Microscopy and by Low Energy Electron Diffraction, shows a
good agreement with the geometrical model.Comment: 20 pages, 9 figure
Parametric oscillator based on non-linear vortex dynamics in low resistance magnetic tunnel junctions
Radiofrequency vortex spin-transfer oscillators based on magnetic tunnel
junctions with very low resistance area product were investigated. A high power
of excitations has been obtained characterized by a power spectral density
containing a very sharp peak at the fundamental frequency and a series of
harmonics. The observed behaviour is ascribed to the combined effect of spin
transfer torque and Oersted-Amp\`ere field generated by the large applied
dc-current. We furthermore show that the synchronization of a vortex
oscillation by applying a ac bias current is mostly efficient when the external
frequency is twice the oscillator fundamental frequency. This result is
interpreted in terms of a parametric oscillator.Comment: 4 pages, 4 figure
Epitaxial rhenium microwave resonators
International audienceWe have fabricated rhenium microwave resonators from epitaxial films. We have used thin films of different structural quality depending on their growth conditions. The resonators were coupled to a microwave transmission line which allows the measurement of their resonance frequencies and internal quality factors. From the resonance frequency at low temperature , the effective penetration depth and the London penetration depth of the rhenium film are extracted
Evolution and diversification within the intertidal brown macroalgae Fucus spiralis/F. vesiculosus species complex in the North Atlantic
We examined 733 individuals of Fucusspiralis from 21 locations and 1093 Fucusvesiculosus individuals from 37 locations throughout their northern hemisphere ranges using nuclear and mitochondrial markers. Three genetic entities of F. spiralis were recovered. In northern and sympatric populations, the presence of "F. spiralis Low" in the mid-intertidal and "F. spiralis High" in the high-intertidal was confirmed and both co-occurred with the sister species F. vesiculosus. The third and newly-discovered entity, "F. spiralis South", was present mainly in the southern range, where it did not co-occur with F. vesiculosus. The South entity diverged early in allopatry, then hybridized with F. vesiculosus in sympatry to produce F. spiralis Low. Ongoing parallel evolution of F. spiralis Low and F. spiralis High is most likely due to habitat preference/local selection and maintained by preferentially selfing reproductive strategies. Contemporary populations of F. spiralis throughout the North Atlantic stem from a glacial refugium around Brittany involving F. spiralis High; F. spiralis South was probably unaffected by glacial episodes. Exponential population expansion for F. vesiculosus began during the Cromer and/Holstein interglacial period (300,000-200,000 yrs BP). Following the last glacial maximum (30,000-22,000 yrs BP), a single mtDNA haplotype from a glacial refugium in SW Ireland colonized Scandinavia, the Central Atlantic islands, and the W Atlantic
A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs. Although airway epithelial cells represent an important target for infection, the respiratory epithelium is also composed of an elaborate network of dendritic cells (DCs) that are essential sentinels of the immune system, sensing pathogens and presenting foreign antigens to T lymphocytes. In this report, we show that in vitro infection by human coronavirus 229E (HCoV-229E) induces massive cytopathic effects in DCs, including the formation of large syncytia and cell death within only few hours. In contrast, monocytes are much more resistant to infection and cytopathic effects despite similar expression levels of CD13, the membrane receptor for HCoV-229E. While the differentiation of monocytes into DCs in the presence of granulocyte-macrophage colony-stimulating factor and interleukin-4 requires 5 days, only 24 h are sufficient for these cytokines to sensitize monocytes to cell death and cytopathic effects when infected by HCoV-229E. Cell death induced by HCoV-229E is independent of TRAIL, FasL, tumor necrosis factor alpha, and caspase activity, indicating that viral replication is directly responsible for the observed cytopathic effects. The consequence of DC death at the early stage of HCoV-229E infection may have an impact on the early control of viral dissemination and on the establishment of long-lasting immune memory, since people can be reinfected multiple times by HCoV-229E
Variability and connectivity of plaice populations from the Eastern North Sea to the Western Baltic Sea, and implications for assessment and management
An essential prerequisite of sustainable fisheries is the match between biologically relevant processes and management action. Various populations may however co-occur on fishing grounds, although they might not belong to the same stock, leading to poor performance of stock assessment and management. Plaice in Kattegat and Skagerrak have traditionally been considered as one stock unit. Current understanding indicates that several plaice components may exist in the transition area between the North Sea and the Baltic Sea. A comprehensive review of all available biological knowledge on plaice in this area is performed, including published and unpublished literature together with the analyses of commercial and survey data and historical tagging data. The results suggest that plaice in Skagerrak is closely associated with plaice in the North Sea, although local populations are present in the area. Plaice in Kattegat, the Belts Sea and the Sound can be considered a stock unit, as is plaice in the Baltic Sea. The analyses revealed great heterogeneity in the dynamics and productivity of the various local components, and suggested for specific action to maintain biodiversity
Multi-wave coherent control of a solid-state single emitter
The authors acknowledge support by the European Research Council Starting Grant 'PICSEN' contract no. 306387.Coherent control of individual two-level systems (TLSs) is at the basis of any implementation of quantum information. An impressive level of control is now achieved using nuclear, vacancies and charge spins. Manipulation of bright exciton transitions in semiconductor quantum dots (QDs) is less advanced, principally due to the sub-nanosecond dephasing. Conversely, owing to their robust coupling to light, one can apply tools of nonlinear spectroscopy to achieve all-optical command. Here, we report on the coherent manipulation of an exciton via multi-wave mixing. Specifically, we employ three resonant pulses driving a single InAs QD. The first two induce a four-wave mixing (FWM) transient, which is projected onto a six-wave mixing (SWM) depending on the delay and area of the third pulse, in agreement with analytical predictions. Such a switch enables to demonstrate the generation of SWM on a single emitter and to engineer the spectro-temporal shape of the coherent response originating from a TLS. These results pave the way toward multi-pulse manipulations of solid state qubits via implementing the NMR-like control schemes in the optical domain.PostprintPeer reviewe
Aerodynamic drag reduction of a tilt rotor aircraft using zero-net-mass-flux devices
The study described in this paper was conducted as part of the European
Funded CleanSky2 project AFC4TR (Active Flow Control for Tilt-Rotor aircraft).
High Fidelity numerical simulations were made to study various approaches of
using Active Flow Control (AFC) actuators to delay flow separation at near
stall conditions of the Next Generation Civil Tilt Rotor (NGCTR) VTOL aircraft
with a tilted nacelle used during take-off and landing. The study revealed that
for this configuration the flow separations travel in the spanwise direction
starting from the middle of the wing. Various flow control strategies using
Zero Net Mass Flux (ZNMF) actuators (synthetic jets) were then tested.
Different number of actuators were integrated on the wing at different
positions in order to optimize the effectiveness of these devices. It was found
that when placed correctly, using the optimal blowing velocity and actuation
frequency, ZNMF devices help to delay flow separation, resulting in a reduction
of pressure drag and an increase in the aircraft's aerodynamic efficiency
Effect of synbiotic supplementation in children and adolescents with cystic fibrosis: a randomized controlled clinical trial
BACKGROUND/OBJECTIVES:Cystic fibrosis (CF) is characterized by excessive activation of immune processes. The aim of this study was to evaluate the effect of synbiotic supplementation on the inflammatory response in children/adolescents with CF.
SUBJECTS/METHODS:A randomized, placebo-controlled, double-blind, clinical-trial was conducted with control group (CG, n = 17), placebo-CF-group (PCFG, n = 19), synbiotic CF-group (SCFG, n = 22), PCFG negative (n = 8) and positive (n = 11) bacteriology, and SCFG negative (n = 12) and positive (n = 10) bacteriology. Markers of lung function (FEV1), nutritional status [body mass index-for age (BMI/A), height-for-age (H/A), weight-for-age (W/A), upper-arm fat area (UFA), upper-arm muscle area (UMA), body fat (%BF)], and inflammation [interleukin (IL)-12, tumor necrosis factor-alpha (TNF-α), IL-10, IL-6, IL-1β, IL-8, myeloperoxidase (MPO), nitric oxide metabolites (NOx)] were evaluated before and after 90-day of supplementation with a synbiotic.
RESULTS:No significance difference was found between the baseline and end evaluations of FEV1 and nutricional status markers. A significant interaction (time vs. group) was found for IL-12 (p = 0.010) and myeloperoxidase (p = 0.036) between PCFG and SCFG, however, the difference was not maintained after assessing the groups individually. NOx diminished significantly after supplementation in the SCFG (p = 0.030). In the SCFG with positive bacteriology, reductions were found in IL-6 (p = 0.033) and IL-8 (p = 0.009) after supplementation.
CONCLUSIONS: Synbiotic supplementation shown promise at diminishing the pro-inflammatory markers IL-6, IL-8 in the SCFG with positive bacteriology and NOx in the SCFG in children/adolescents with CF
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