7,578 research outputs found
Trapped ion scaling with pulsed fast gates
Fast entangling gates for trapped ions offer vastly improved gate operation
times relative to implemented gates, as well as approaches to trap scaling.
Gates on neighbouring ions only involve local ions when performed sufficiently
fast, and we find that even a fast gate between distant ions with few degrees
of freedom restores all the motional modes given more stringent gate speed
conditions. We compare pulsed fast gate schemes, defined by a timescale faster
than the trap period, and find that our proposed scheme has less stringent
requirements on laser repetition rate for achieving arbitrary gate time targets
and infidelities well below . By extending gate schemes to ion
crystals, we explore the effect of ion number on gate fidelity for coupling
neighbouring pairs of ions in large crystals. Inter-ion distance determines the
gate time, and a factor of five increase in repetition rate, or correspondingly
the laser power, reduces the infidelity by almost two orders of magnitude. We
also apply our fast gate scheme to entangle the first and last ions in a
crystal. As the number of ions in the crystal increases, significant increases
in the laser power are required to provide the short gate times corresponding
to fidelity above 0.99.Comment: 29 pages, 10 figure
A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networks
Background
Transcription regulatory networks are composed of interactions between transcription factors and their target genes. Whereas unicellular networks have been studied extensively, metazoan transcription regulatory networks remain largely unexplored. Caenorhabditis elegans provides a powerful model to study such metazoan networks because its genome is completely sequenced and many functional genomic tools are available. While C. elegans gene predictions have undergone continuous refinement, this is not true for the annotation of functional transcription factors. The comprehensive identification of transcription factors is essential for the systematic mapping of transcription regulatory networks because it enables the creation of physical transcription factor resources that can be used in assays to map interactions between transcription factors and their target genes.
Results
By computational searches and extensive manual curation, we have identified a compendium of 934 transcription factor genes (referred to as wTF2.0). We find that manual curation drastically reduces the number of both false positive and false negative transcription factor predictions. We discuss how transcription factor splice variants and dimer formation may affect the total number of functional transcription factors. In contrast to mouse transcription factor genes, we find that C. elegans transcription factor genes do not undergo significantly more splicing than other genes. This difference may contribute to differences in organism complexity. We identify candidate redundant worm transcription factor genes and orthologous worm and human transcription factor pairs. Finally, we discuss how wTF2.0 can be used together with physical transcription factor clone resources to facilitate the systematic mapping of C. elegans transcription regulatory networks.
Conclusion
wTF2.0 provides a starting point to decipher the transcription regulatory networks that control metazoan development and function
Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo
In contrast to the results of previous in vitro studies, experimental infection of calves with noncytopathic bovine viral diarrhea virus (ncpBVDV) was found to induce strong alpha/beta and gamma interferon responses in gnotobiotic animals. These responses were associated with depressed levels of transforming growth factor β (TGF-β) in serum. The results of this study indicate that the immunosuppression caused by ncpBVDV is not associated with low interferon responses or elevated levels of TGF-β
Fast gates for ion traps by splitting laser pulses
We present a fast phase gate scheme that is experimentally achievable and has
an operation time more than two orders of magnitude faster than current
experimental schemes for low numbers of pulses. The gate time improves with the
number of pulses following an inverse power law. Unlike implemented schemes
which excite precise motional sidebands, thus limiting the gate timescale, our
scheme excites multiple motional states using discrete ultra-fast pulses. We
use beam-splitters to divide pulses into smaller components to overcome
limitations due to the finite laser pulse repetition rate. This provides gate
times faster than proposed theoretical schemes when we optimise a practical
setup.Comment: 20 pages, 8 figure
Outcoupling from a Bose-Einstein condensate with squeezed light to produce entangled atom laser beams
We examine the properties of an atom laser produced by outcoupling from a
Bose-Einstein condensate with squeezed light. We model the multimode dynamics
of the output field and show that a significant amount of squeezing can be
transfered from an optical mode to a propagating atom laser beam. We use this
to demonstrate that two-mode squeezing can be used to produce twin atom laser
beams with continuous variable entanglement in amplitude and phase.Comment: 11 pages, 14 figure
Pulse retrieval and soliton formation in a non-standard scheme for dynamic electromagnetically induced transparency
We examine in detail an alternative method of retrieving the information
written into an atomic ensemble of three-level atoms using electromagnetically
induced transparency. We find that the behavior of the retrieved pulse is
strongly influenced by the relative collective atom-light coupling strengths of
the two relevant transitions. When the collective atom-light coupling strength
for the retrieval beam is the stronger of the two transitions, regeneration of
the stored pulse is possible. Otherwise, we show the retrieval process can lead
to creation of soliton-like pulses.Comment: 11 figure
Fast gates for ion traps by splitting laser pulses
We present a fast phase gate scheme that is experimentally achievable and has an operation time more than two orders of magnitude faster than current experimental schemes for low numbers of pulses. The gate time improves with the number of pulses following an inverse power law. Unlike
implemented schemes which excite precise motional sidebands, thus limiting
the gate timescale, our scheme excites multiple motional states using discrete
ultra-fast pulses.We use beam-splitters to divide pulses into smaller components
to overcome limitations due to the finite laser pulse repetition rate. This provides
gate times faster than proposed theoretical schemes when we optimize a practical
setup
Smallholder Participation in Agricultural Value Chains: Comparative Evidence from Three Continents
Supermarkets, specialized wholesalers, and processors and agro-exporters’ agricultural value chains have begun to transform the marketing channels into which smallholder farmers sell produce in low-income economies. We develop a conceptual framework through which to study contracting between smallholders and a commodity-processing firm. We then conduct an empirical meta-analysis of agricultural value chains in five countries across three continents (Ghana, India, Madagascar, Mozambique, and Nicaragua). We document patterns of participation, the welfare gains associated with participation, reasons for non-participation, the significant extent of contract non-compliance, and the considerable dynamism of these value chains, as farmers and firms enter and exit frequently.Agricultural Value Chains, Contract Farming, Africa, Asia, Latin America
Exact solution, scaling behaviour and quantum dynamics of a model of an atom-molecule Bose-Einstein condensate
We study the exact solution for a two-mode model describing coherent coupling
between atomic and molecular Bose-Einstein condensates (BEC), in the context of
the Bethe ansatz. By combining an asymptotic and numerical analysis, we
identify the scaling behaviour of the model and determine the zero temperature
expectation value for the coherence and average atomic occupation. The
threshold coupling for production of the molecular BEC is identified as the
point at which the energy gap is minimum. Our numerical results indicate a
parity effect for the energy gap between ground and first excited state
depending on whether the total atomic number is odd or even. The numerical
calculations for the quantum dynamics reveals a smooth transition from the
atomic to the molecular BEC.Comment: 5 pages, 4 figure
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