Model of the early development of thalamo-cortical connections and area patterning via signaling molecules

The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors. The latter were recently implicated as dominating the early cortical area specification. In this paper, we present a theoretical model that explicitly considers the genetic factors and that is able to explain several sets of experiments on cortical area regulation involving transcription factors Emx2 and Pax6, and fibroblast growth factor FGF8. The model consists of the dynamics of thalamo- cortical connections modulated by signaling molecules that are regulated genetically, and by axonal competition for neocortical space. The model can make predictions and provides a basic mathematical framework for the early development of the thalamo-cortical connections and area patterning that can be further refined as more experimental facts become known.Comment: brain, model, neural development, cortical area patterning, signaling molecule

Improved error bounds for approximations to the stop loss transform of compound distributions.

In the present note we deduce a class of bounds for the difference between the stop loss transforms of two compound distributions with the same severity distribution. The class contains bounds of any degree of accuracy in the sense that the bounds can be chosen as close to the exact value as desired; the time required to compute the bounds increases with the accuracy.Distribution;

Multiloop functional renormalization group for general models

We present multiloop flow equations in the functional renormalization group (fRG) framework for the four-point vertex and self-energy, formulated for a general fermionic many-body problem. This generalizes the previously introduced vertex flow [F. B. Kugler and J. von Delft, Phys. Rev. Lett. 120, 057403 (2018)] and provides the necessary corrections to the self-energy flow in order to complete the derivative of all diagrams involved in the truncated fRG flow. Due to its iterative one-loop structure, the multiloop flow is well-suited for numerical algorithms, enabling improvement of many fRG computations. We demonstrate its equivalence to a solution of the (first-order) parquet equations in conjunction with the Schwinger-Dyson equation for the self-energy

Multiloop functional renormalization group that sums up all parquet diagrams

We present a multiloop flow equation for the four-point vertex in the functional renormalization group (fRG) framework. The multiloop flow consists of successive one-loop calculations and sums up all parquet diagrams to arbitrary order. This provides substantial improvement of fRG computations for the four-point vertex and, consequently, the self-energy. Using the X-ray-edge singularity as an example, we show that solving the multiloop fRG flow is equivalent to solving the (first-order) parquet equations and illustrate this with numerical results

Null Half-Supersymmetric Solutions in Five-Dimensional Supergravity

We classify half-supersymmetric solutions of gauged N=2, D=5 supergravity coupled to an arbitrary number of abelian vector multiplets for which all of the Killing spinors generate null Killing vectors. We show that there are four classes of solutions, and in each class we find the metric, scalars and gauge field strengths. When the scalar manifold is symmetric, the solutions correspond to a class of local near horizon geometries recently found by Kunduri and Lucietti.Comment: 46 pages, typos corrected and reference added. Section 7.1 has been added: it is shown that the solutions found here correspond to a class of solutions found in arXiv:0708.3695. Uses JHEP3.cl

Concentric Black Rings

We present new supersymmetric solutions of five-dimensional minimal supergravity that describe concentric black rings with an optional black hole at the common centre. Configurations of two black rings are found which have the same conserved charges as a single rotating black hole; these black rings can have a total horizon area less than, equal to, or greater than the black hole with the same charges. A numerical investigation of these particular black ring solutions suggests that they do not have closed timelike curves.Comment: 7 pages, minor alterations, typos corrected. Version to be published in PR