Near infrared spectroscopy for fibre based gas detection

Gas sensing systems based on fibre optic linked near infra red absorption cells are potentially a flexible and effective tool for monitoring accumulations of hazardous and noxious gases in enclosed areas such as tunnels and mines. Additionally the same baseline technology is readily modified to measure concentrations of hydrocarbon fuels - notably but not exclusively methane, and monitoring emissions of greenhouse gases. Furthermore the system can be readily implemented to provide intrinsically safe monitoring over extensive areas at up to ~250 points from a single interrogation unit. In this paper we review our work on fibre coupled gas sensing systems. We outline the basic principles through which repeatable and accurate self calibrating gas measurements may be realised, including the recover of detailed line shapes for non contact temperature and / or pressure measurements in addition to concentration assessments in harsh environments. We also outline our experience in using these systems in extensive networks operating under inhospitable conditions over extended periods extending to several years

Response analysis of an automobile shipping container

The design and development of automobile shipping containers to reduce enroute damage are discussed. Vibration tests were conducted to determine the system structural integrity. A dynamic analysis was made using NASTRAN and the results of the test and the analysis are compared

How sex-biased dispersal affects conflict over parental investment

This article is a preprint and has not been peer-reviewed. It is availble from bioRxiv via the DOI in this record.Existing models of parental investment have mainly focused on interactions at the level of the family, and have paid much less attention to the impact of population-level processes. Here we extend classical models of parental care to assess the impact of population structure and limited dispersal. We find that sex-differences in dispersal substantially affect the amount of care provided by each parent, with the more philopatric sex providing the majority of the care to young. This effect is most pronounced in highly viscous populations: in such cases, when classical models would predict stable biparental care, inclusion of a modest sex difference in dispersal leads to uniparental care by the philopatric sex. In addition, mating skew also affects sex-differences in parental investment, with the more numerous sex providing most of the care. However, the effect of mating skew only holds when parents care for their own offspring. When individuals breed communally, we recover the previous finding that the more philopatric sex provides most of the care, even when it is the rare sex. Finally, we show that sex-differences in dispersal can mask the existence of sex-specific costs of care, because the philopatric sex may provide most of the care even in the face of far higher mortality costs relative to the dispersing sex. We conclude that sex-biased dispersal is likely to be an important, yet currently overlooked driver of sex-differences in parental care.We would like to thank the other members of the Transgen group, Tom Ezard, Stuart Townley and Jonathan Wells for discussion. The Dutch Academy of Arts and Sciences (KNAW) and the Lorentz Centre at the University of Leiden, the Netherlands, funded a week-long workshop on nongenetic effects that contributed to this paper. The authors acknowledge the use of the UCL Legion High Performance Computing Facility (Legion@UCL), and associated support services, in the completion of this work. This study was funded by an EPSRC sandpit grant on transgenerational effects, grant number EP/H031928/1 awarded to RAJ and an EPSRC-funded 2020 Science fellowship awarded to BK (grant number EP/I017909/1)

The Infrared and Radio Fluxes Densities of Galactic HII Regions

We derive infrared and radio flux densities of all ~1000 known Galactic HII regions in the Galactic longitude range 17.5 < l < 65 degree. Our sample comes from the Wide-Field Infrared Survey Explorer (WISE) catalog of Galactic \hii regions \citep{anderson2014}. We compute flux densities at six wavelengths in the infrared (GLIMPSE 8 microns, WISE 12 microns and 22 microns, MIPSGAL 24 microns, and Hi-GAL 70 microns and 160 microns) and two in the radio (MAGPIS 20 cm and VGPS 21 cm). All HII region infrared flux densities are strongly correlated with their ~20 cm flux densities. All HII regions used here, regardless of physical size or Galactocentric radius, have similar infrared to radio flux density ratios and similar infrared colors, although the smallest regions ($r<1\,$pc), have slightly elevated IR to radio ratios. The colors $\log_{10}(F_{24 micron}/F_{12 micron}) \ge 0$ and $\log_{10}(F_{70 micron}/F_{12 micron}) \ge 1.2$, and $\log_{10}(F_{24 micron}/F_{12 micron}) \ge 0$ and $\log_{10}(F_{160 micron}/F_{70 micron}) \le 0.67$ reliably select HII regions, independent of size. The infrared colors of ~22$\%$ of HII regions, spanning a large range of physical sizes, satisfy the IRAS color criteria of \citet{wood1989} for HII regions, after adjusting the criteria to the wavelengths used here. Since these color criteria are commonly thought to select only ultra-compact HII regions, this result indicates that the true ultra-compact HII region population is uncertain. Comparing with a sample of IR color indices from star-forming galaxies, HII regions show higher $\log_{10}(F_{70 micron}/F_{12 micron})$ ratios. We find a weak trend of decreasing infrared to ~20 cm flux density ratios with increasing $R_{gal}$, in agreement with previous extragalactic results, possibly indicating a decreased dust abundance in the outer Galaxy.Comment: 27 pages, 16 figures, 5 table

Dynamics of Dense Cores in the Perseus Molecular Cloud

We survey the kinematics of over one hundred and fifty candidate (and potentially star-forming) dense cores in the Perseus molecular cloud with pointed N2H+(1-0) and simultaneous C18O(2-1) observations. Our detection rate of N2H+ is 62%, rising to 84% for JCMT SCUBA-selected targets. In agreement with previous observations, we find that the dense N2H+ targets tend to display nearly thermal linewidths, particularly those which appear to be starless (using Spitzer data), indicating turbulent support on the small scales of molecular clouds is minimal. For those N2H+ targets which have an associated SCUBA dense core, we find their internal motions are more than sufficient to provide support against the gravitational force on the cores. Comparison of the N2H+ integrated intensity and SCUBA flux reveals fractional N2H+ abundances between 10^-10 and 10^-9. We demonstrate that the relative motion of the dense N2H+ gas and the surrounding C18O gas is less than the sound speed in the vast majority of cases (~90%). The point-to-point motions we observe within larger extinction regions appear to be insufficient to provide support against gravity, although we sparsely sample these regions.Comment: 49 pages, 20 figures. Accepted for publication in the Astrophysical Journa

Autistic traits modulate frontostriatal connectivity during processing of rewarding faces

Deficits in facial mimicry have been widely reported in autism. Some studies have suggested that these deficits are restricted to spontaneous mimicry and do not extend to volitional mimicry. We bridge these apparently inconsistent observations, by testing the impact of reward value on neural indices of mimicry, and how autistic traits modulate this impact. Neutral faces were conditioned with high and low reward. Subsequently, functional connectivity between the ventral striatum (VS) and inferior frontal gyrus (IFG) was measured whilst neurotypical adults (n = 30) watched happy expressions made by these conditioned faces. We found greater VS-IFG connectivity in response to high-reward vs. low-reward happy faces. This difference was negatively proportional to autistic traits, suggesting that reduced spontaneous mimicry of social stimuli seen in autism, maybe related to a failure in the modulation of the mirror system by the reward system rather than a circumscribed deficit in the mirror system

Partnership is alive and underpinning healthcare delivery

YesBryan McIntosh, senior lecturer in health management and organisational behaviour at the University of Bradford, explores the role of partnerships in the health service

Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance

During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling. These events are crucial for successful placentation and the provision of an adequate blood supply to the developing fetus. Remodelling of spiral arteries is impaired in the dangerous pregnancy complication pre-eclampsia. We studied dNK cells isolated from pregnancies at 9-14 weeks' gestation, screened by uterine artery Doppler ultrasound to determine resistance indices which relate to the extent of spiral artery remodelling. dNK cells were able to promote the invasive behaviour of fetal trophoblast cells, partly through HGF. Cells isolated from pregnancies with higher resistance indices were less able to do this and secreted fewer pro-invasive factors. dNK cells from pregnancies with normal resistance indices could induce apoptotic changes in vascular smooth muscle and endothelial cells in vitro, events of importance in vessel remodelling, partly through Fas signalling. dNK cells isolated from high resistance index pregnancies failed to induce vascular apoptosis and secreted fewer pro-apoptotic factors. We have modelled the cellular interactions at the maternal-fetal interface and provide the first demonstration of a functional role for dNK cells in influencing vascular cells. A potential mechanism contributing to impaired vessel remodelling in pregnancies with a higher uterine artery resistance is presented. These findings may be informative in determining the cellular interactions contributing to the pathology of pregnancy disorders where remodelling is impaired, such as pre-eclampsia. Copyright © 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd

Large Area Mapping at 850 Microns. V. Analysis of the Clump Distribution in the Orion A South Molecular Cloud

We present results from a 2300 arcmin^2 survey of the Orion A molecular cloud at 450 and 850 micron using the Submillimetre Common-User Bolometer Array (SCUBA) on the James Clerk Maxwell Telescope. The region mapped lies directly south of the OMC1 cloud core and includes OMC4, OMC5, HH1/2, HH34, and L1641N. We identify 71 independent clumps in the 850 micron map and compute size, flux, and degree of central concentration in each. Comparison with isothermal, pressure-confined, self-gravitating Bonnor-Ebert spheres implies that the clumps have internal temperatures T_d ~ 22 +/- K and surface pressures log (k^-1 P cm^-3 K) = 6.0 +/- 0.2. The clump masses span the range 0.3 - 22 Msun assuming a dust temperature T_d ~ 20 K and a dust emissivity kappa_850 = 0.02 cm^2 g^-1. The distribution of clump masses is well characterized by a power-law N(M) propto M^-alpha with alpha = 2.0 +/- 0.5 for M > 3.0 Msun, indicating a clump mass function steeper than the stellar Initial Mass Function. Significant incompleteness makes determination of the slope at lower masses difficult. A comparison of the submillimeter emission map with an H_2 2.122 micron survey of the same region is performed. Several new Class 0 sources are revealed and a correlation is found between both the column density and degree of concentration of the submillimeter sources and the likelihood of coincident H_2 shock emission.Comment: 44 pages, 17 figures, accepted by Ap