Variants of the human PPARG locus and the susceptibility to chronic periodontitis

Apart from its regulatory function in lipid and glucose metabolism, peroxisome proliferator-activated receptor (PPAR)γ has impact on the regulation of inflammation and bone metabolism. The aim of the study was to investigate the association of five polymorphisms (rs10865710, rs2067819, rs3892175, rs1801282, rs3856806) within the PPARG gene with chronic periodontitis. The study population comprised 402 periodontitis patients and 793 healthy individuals. Genotyping of the PPARG gene polymorphisms was performed by PCR and melting curve analysis. Comparison of frequency distribution of genotypes between individuals with periodontal disease and healthy controls for the polymorphism rs3856806 showed a P-value of 0.04 but failed to reach significance after correction for multiple testing (P  0.90). A 3-site analysis (rs2067819-rs1801282-rs3856860) revealed five haplotypes with a frequency of ≥1% among cases and controls. Following adjustment for age, gender and smoking, none of the haplotypes was significantly different between periodontitis and healthy controls after Bonferroni correction. This study could not show a significant association between PPARG gene variants and chronic periodontitis

Phonon-affected steady-state transport through molecular quantum dots

We consider transport through a vibrating molecular quantum dot contacted to macroscopic leads acting as charge reservoirs. In the equilibrium and nonequilibrium regime, we study the formation of a polaron-like transient state at the quantum dot for all ratios of the dot-lead coupling to the energy of the local phonon mode. We show that the polaronic renormalization of the dot-lead coupling is a possible mechanism for negative differential conductance. Moreover, the effective dot level follows one of the lead chemical potentials to enhance resonant transport, causing novel features in the inelastic tunneling signal. In the linear response regime, we investigate the impact of the electron-phonon interaction on the thermoelectrical properties of the quantum dot device.Comment: 11 pages, 7 figures, FQMT11 Proceeding

Reconstructing the geometric structure of a Riemannian symmetric space from its Satake diagram

The local geometry of a Riemannian symmetric space is described completely by the Riemannian metric and the Riemannian curvature tensor of the space. In the present article I describe how to compute these tensors for any Riemannian symmetric space from the Satake diagram, in a way that is suited for the use with computer algebra systems. As an example application, the totally geodesic submanifolds of the Riemannian symmetric space SU(3)/SO(3) are classified. The submission also contains an example implementation of the algorithms and formulas of the paper as a package for Maple 10, the technical documentation for this implementation, and a worksheet carrying out the computations for the space SU(3)/SO(3) used in the proof of Proposition 6.1 of the paper.Comment: 23 pages, also contains two Maple worksheets and technical documentatio

Compression of sub-relativistic space-charge-dominated electron bunches for single-shot femtosecond electron diffraction

We demonstrate compression of 95 keV, space-charge-dominated electron bunches to sub-100 fs durations. These bunches have sufficient charge (200 fC) and are of sufficient quality to capture a diffraction pattern with a single shot, which we demonstrate by a diffraction experiment on a polycrystalline gold foil. Compression is realized by means of velocity bunching as a result of a velocity chirp, induced by the oscillatory longitudinal electric field of a 3 GHz radio-frequency cavity. The arrival time jitter is measured to be 80 fs

Division, adjoints, and dualities of bilinear maps

The distributive property can be studied through bilinear maps and various morphisms between these maps. The adjoint-morphisms between bilinear maps establish a complete abelian category with projectives and admits a duality. Thus the adjoint category is not a module category but nevertheless it is suitably familiar. The universal properties have geometric perspectives. For example, products are orthogonal sums. The bilinear division maps are the simple bimaps with respect to nondegenerate adjoint-morphisms. That formalizes the understanding that the atoms of linear geometries are algebraic objects with no zero-divisors. Adjoint-isomorphism coincides with principal isotopism; hence, nonassociative division rings can be studied within this framework. This also corrects an error in an earlier pre-print; see Remark 2.11

Uniform electron gases

We show that the traditional concept of the uniform electron gas (UEG) --- a homogeneous system of finite density, consisting of an infinite number of electrons in an infinite volume --- is inadequate to model the UEGs that arise in finite systems. We argue that, in general, a UEG is characterized by at least two parameters, \textit{viz.} the usual one-electron density parameter $\rho$ and a new two-electron parameter $\eta$. We outline a systematic strategy to determine a new density functional $E(\rho,\eta)$ across the spectrum of possible $\rho$ and $\eta$ values.Comment: 8 pages, 2 figures, 5 table

Dynamical Properties of small Polarons

On the basis of the two-site polaron problem, which we solve by exact diagonalization, we analyse the spectral properties of polaronic systems in view of discerning localized from itinerant polarons and bound polaron pairs from an ensemble of single polarons. The corresponding experimental techniques for that concern photoemission and inverse photoemission spectroscopy. The evolution of the density of states as a function of concentration of charge carriers and strength of the electron-phonon interaction clearly shows the opening up of a gap between single polaronic and bi-polaronic states, in analogy to the Hubbard problem for strongly correlated electron systems. The crossover regime between adiabatic and anti-adiabatic small polarons is triggered by two characteristic time scales: the renormalized electron hopping rate and the renormalized vibrational frequency becoming equal. This crossover regime is then characterized by temporarily alternating self- localization and delocalization of the charge carriers which is accompanied by phase slips in the charge and molecular deformation oscillations and ultimately leads to a dephasing between these two dynamical components of the polaron problem. We visualize these features by a study of the temporal evolution of the charge redistribution and the change in molecular deformations. The spectral and dynamical properties of polarons discussed here are beyond the applicability of the standard Lang Firsov approach to the polaron problem.Comment: 31 pages and 23 figs.(eps), accepted in the Phys. Rev.

Quantum Magnetic Algebra and Magnetic Curvature

The symplectic geometry of the phase space associated with a charged particle is determined by the addition of the Faraday 2-form to the standard structure on the Euclidean phase space. In this paper we describe the corresponding algebra of Weyl-symmetrized functions in coordinate and momentum operators satisfying nonlinear commutation relations. The multiplication in this algebra generates an associative product of functions on the phase space. This product is given by an integral kernel whose phase is the symplectic area of a groupoid-consistent membrane. A symplectic phase space connection with non-trivial curvature is extracted from the magnetic reflections associated with the Stratonovich quantizer. Zero and constant curvature cases are considered as examples. The quantization with both static and time dependent electromagnetic fields is obtained. The expansion of the product by the deformation parameter, written in the covariant form, is compared with the known deformation quantization formulas.Comment: 23 page

On Deformations of n-Lie algebras

The aim of this paper is to review the deformation theory of $n$-Lie algebras. We summarize the 1-parameter formal deformation theory and provide a generalized approach using any unital commutative associative algebra as a deformation base. Moreover, we discuss degenerations and quantization of $n$-Lie algebras.Comment: Proceeding of the conference Dakar's Workshop in honor of Pr Amin Kaidi. arXiv admin note: text overlap with arXiv:hep-th/9602016 by other author