4,989 research outputs found
Distributed allocation of mobile sensing swarms in gyre flows
We address the synthesis of distributed control policies to enable a swarm of
homogeneous mobile sensors to maintain a desired spatial distribution in a
geophysical flow environment, or workspace. In this article, we assume the
mobile sensors (or robots) have a "map" of the environment denoting the
locations of the Lagrangian coherent structures or LCS boundaries. Based on
this information, we design agent-level hybrid control policies that leverage
the surrounding fluid dynamics and inherent environmental noise to enable the
team to maintain a desired distribution in the workspace. We establish the
stability properties of the ensemble dynamics of the distributed control
policies. Since realistic quasi-geostrophic ocean models predict double-gyre
flow solutions, we use a wind-driven multi-gyre flow model to verify the
feasibility of the proposed distributed control strategy and compare the
proposed control strategy with a baseline deterministic allocation strategy.
Lastly, we validate the control strategy using actual flow data obtained by our
coherent structure experimental testbed.Comment: 10 pages, 14 Figures, added reference
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If someone cares about you, you are more apt to come around: improving HIV care engagement by strengthening the patient-provider relationship.
Purpose:The patient-provider relationship is a central factor that can promote or hinder long-term engagement in care among people living with chronic illnesses. In this paper, we explore characteristics of the patient-provider relationship that facilitated or hindered engagement in care among patients receiving care at HIV specialty clinics. Patients and methods:We conducted 6 focus group discussions with a total of 43 well-retained and less well-retained HIV+ patients in San Francisco, Seattle, and Birmingham, to elicit a wide range of perspectives on engagement in HIV care. Borrowing from the field of psychotherapy, we examined patient-provider relationship characteristics through the lens of the therapeutic alliance, and with regard to their therapeutic efficacy and impact on patient engagement. Results:The majority of participants emphasized how a strong patient-provider relationship defined by trust, intimacy, and collaboration promoted engagement, while a weak patient-provider relationship impeded engagement. Conclusion:We discuss practical strategies and therapeutic techniques that may be helpful to providers in building strong patient-provider relationship and contend that a strong patient-provider relationship is crucial for patients to feel cared for during clinical encounters, which can promote long-term and sustained engagement in HIV care
Selection of systems to perform extravehicular activities, man and manipulator. Volume 1 - Performance Effectiveness Evaluation Scheme /PEEVS/. Part A - Instructions
Performance effectiveness evaluation scheme for EVA systems selection - instruction
Selection of systems to perform extravehicular activities, man and manipulator. Volume 2 - Final report
Technologies for EVA and remote manipulation systems - handbook for systems designer
Multiwavelength Studies of PSR J1420-6048, a Young Pulsar in the Kookaburra
We present X-ray, radio, and infrared observations of the 68 ms pulsar PSR
J1420-6048 and its surrounding nebula, a possible counterpart of the gamma-ray
source GeV J1417-6100/3EG J1420-6038. Pulsed X-ray emission at the radio period
is marginally detected by ASCA from a source embedded in the hard spectrum
X-ray nebula AX J1420.1-6049. At radio wavelengths, the pulsar is found to be
strongly linearly and circularly polarized, and the polarization sweep is
measured. A comparison of high resolution ATCA radio imaging of the
Kookaburra's upper wing (G313.6+0.3), which contains the pulsar and the X-ray
nebula, with infrared images suggests the radio emission is partly non-thermal.Comment: 8 pages, 4 figures, to appear in Astrophysical Journal Letter
Sheroes: Feasibility and Acceptability of a Community-Driven, Group-Level HIV Intervention Program for Transgender Women.
Transgender women experience disproportionate risk of HIV acquisition and transmission. We piloted 'Sheroes', a peer-led group-level intervention for transgender women of any HIV status emphasizing empowerment and gender affirmation to reduce HIV risk behaviors and increase social support. Participants (N = 77) were randomized to Sheroes (n = 39) or a time- and attention-matched control (n = 38). Sheroes is 5 weekly group sessions; topics include sexuality, communication, gender transition, and coping skills. Control participants attended 5 weekly group movie sessions. At 6-month follow up, HIV-negative and unknown status Sheroes participants reported reductions in condomless intercourse and improved social support compared to control. Among participants living with HIV, both the control and intervention groups reduced their total number of sex partners; this change was sustained at 6-month follow-up for Sheroes participants but not for control participants relative to baseline. Sheroes was deemed highly feasible and acceptable to participants; findings support preliminary efficacy of Sheroes
Novel methods to estimate antiretroviral adherence: protocol for a longitudinal study.
BackgroundThere is currently no gold standard for assessing antiretroviral (ARV) adherence, so researchers often resort to the most feasible and cost-effective methods possible (eg, self-report), which may be biased or inaccurate. The goal of our study was to evaluate the feasibility and acceptability of innovative and remote methods to estimate ARV adherence, which can potentially be conducted with less time and financial resources in a wide range of clinic and research settings. Here, we describe the research protocol for studying these novel methods and some lessons learned.MethodsThe 6-month pilot study aimed to examine the feasibility and acceptability of a remotely conducted study to evaluate the correlation between: 1) text-messaged photographs of pharmacy refill dates for refill-based adherence; 2) text-messaged photographs of pills for pill count-based adherence; and 3) home-collected hair sample measures of ARV concentration for pharmacologic-based adherence. Participants were sent monthly automated text messages to collect refill dates and pill counts that were taken and sent via mobile telephone photographs, and hair collection kits every 2 months by mail. At the study end, feasibility was calculated by specific metrics, such as the receipt of hair samples and responses to text messages. Participants completed a quantitative survey and qualitative exit interviews to examine the acceptability of these adherence evaluation methods. The relationship between the 3 novel metrics of adherence and self-reported adherence will be assessed.DiscussionInvestigators conducting adherence research are often limited to using either self-reported adherence, which is subjective, biased, and often overestimated, or other more complex methods. Here, we describe the protocol for evaluating the feasibility and acceptability of 3 novel and remote methods of estimating adherence, with the aim of evaluating the relationships between them. Additionally, we note the lessons learned from the protocol implementation to date. We expect that these novel measures will be feasible and acceptable. The implications of this research will be the identification and evaluation of innovative and accurate metrics of ARV adherence for future implementation
G313.3+00.3: A New Planetary Nebula discovered by the Australia Telescope Compact Array and the Spitzer Space Telescope
We present a new planetary nebula, first identified in images from the
Australia Telescope Compact Array, although not recognized at that time. Recent
observations with the Spitzer Space Telescope during the GLIMPSE Legacy program
have rediscovered the object. The high-resolution radio and infrared images
enable the identification of the central star or its wind, the recognition of
the radio emission as thermal, and the probable presence of polycylic aromatic
hydrocarbons in and around the source. These lead to the conclusion that
G313.3+00.3 is a planetary nebula. This object is of particular interest
because it was discovered solely through radio and mid-infrared imaging,
without any optical (or near-infrared) confirmation, and acts as a proof of
concept for the discovery of many more highly extinguished planetary nebulae.
G313.3+00.3 is well-resolved by both the instruments with which it was
identified, and suffers extreme reddening due to its location in the
Scutum-Crux spiral arm.Comment: 18 pages, LaTeX (aastex), incl. 8 PostScript (eps) figures and 1
table. Accepted by ApJ (Part 1
Discovery of a New Transient Magnetar Candidate: XTE J1810-197
We report the discovery of a new X-ray pulsar, XTE J1810-197. The source was
serendipitously discovered on 2003 July 15 by the Rossi X-ray Timing Explorer
(RXTE) while observing the soft gamma repeater SGR 1806-20. The pulsar has a
5.54 s spin-period and a soft spectrum (photon index ~ 4). We detect the source
in earlier RXTE observations back to 2003 January. These show that a transient
outburst began between 2002 November 17 and 2003 January 23 and that the pulsar
has been spinning down since then, with a high rate Pdot ~ 10^-11 s/s showing
significant timing noise, but no evidence for Doppler shifts due to a binary
companion. The rapid spin-down rate and slow spin-period imply a super-critical
magnetic field B=3x10^14 G and a young characteristic age < 7600 yr. These
properties are strikingly similar to those of anomalous X-ray pulsars and soft
gamma repeaters, making the source a likely new magnetar. A follow-up Chandra
observation provided a 2".5 radius error circle within which the 1.5 m
Russian-Turkish Optical Telescope RTT150 found a limiting magnitude of
R_c=21.5, in accord with other recently reported limits. The source is present
in archival ASCA and ROSAT data as well, at a level 100 times fainter than the
\~ 3 mCrab seen in 2003. This suggests that other X-ray sources that are
currently in a state similar to the inactive phase of XTE J1810-197 may also be
unidentified magnetars awaiting detection via a similar activity.Comment: Submitted to ApJL; 4 pages; 4 figure
Small RNA Profile in Moso Bamboo Root and Leaf Obtained by High Definition Adapters
Moso bamboo (Phyllostachy heterocycla cv. pubescens L.) is an economically important fast-growing tree. In order to gain better understanding of gene expression regulation in this important species we used next generation sequencing to profile small RNAs in leaf and roots of young seedlings. Since standard kits to produce cDNA of small RNAs are biased for certain small RNAs, we used High Definition adapters that reduce ligation bias. We identified and experimentally validated five new microRNAs and a few other small non-coding RNAs that were not microRNAs. The biological implication of microRNA expression levels and targets of microRNAs are discussed
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