Solar microclimatology

It has become apparent in recent years that solar energy can be used for electric power production by several methods. Because of the diffuse nature of the solar insolation, the area involved in any central power plant design can encompass several square miles. A detailed design of these large area collection systems will require precise knowledge of the local solar insolation. Detailed information will also be needed concerning the temporal nature of the insolation and the local spatial distribution. Therefore, insolation data was collected and analyzed for a network of sensors distributed over an area of several square kilometers in Arizona. The analyses of this data yielded probability distributions of cloud size, velocity, and direction of motion which were compared with data obtained from the National Weather Service. Microclimatological analyses were also performed for suitable modeling parameters pertinent to large scale electric power plant design. Instrumentation used to collect the data is described

An Evolutionary Algorithm to Generate Real Urban Traffic Flows

In this article we present a strategy based on an evolutionary algorithm to calculate the real vehicle ows in cities according to data from sensors placed in the streets. We have worked with a map imported from OpenStreetMap into the SUMO traffic simulator so that the resulting scenarios can be used to perform different optimizations with the confidence of being able to work with a traffic distribution close to reality. We have compared the results of our algorithm to other competitors and achieved results that replicate the real traffic distribution with a precision higher than 90%.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. This research has been partially funded by project number 8.06/5.47.4142 in collaboration with the VSB-Technical University of Ostrava and Universidad de Málaga UMA/FEDER FC14-TIC36, programa de fortalecimiento de las capacidades de I+D+i en las universidades 2014-2015, de la Consejería de Economía, Innovación, Ciencia y Empleo, cofinanciado por el fondo europeo de desarrollo regional (FEDER). Also, partially funded by the Spanish MINECO project TIN2014-57341-R (http://moveon.lcc.uma.es). The authors would like to thank the FEDER of European Union for financial support via project Movilidad Inteligente: Wi-Fi, Rutas y Contaminación (maxCT) of the "Programa Operativo FEDER de Andalucía 2014-2020. We also thank all Agency of Public Works of Andalusia Regional Government staff and researchers for their dedication and professionalism. Daniel H. Stolfi is supported by a FPU grant (FPU13/00954) from the Spanish Ministry of Education, Culture and Sports

An identity crisis: the need for core competencies in undergraduate medical education

A medical student perspective on the role of core competencies in undergraduate medical education in light of medical education reform associated with recent Flexner II

Microtubules gate tau condensation to spatially regulate microtubule functions.

Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer's disease and other types of dementia1, yet the physiological state of tau molecules within cells remains unclear. Using single-molecule imaging, we directly observe that the microtubule lattice regulates reversible tau self-association, leading to localized, dynamic condensation of tau molecules on the microtubule surface. Tau condensates form selectively permissible barriers, spatially regulating the activity of microtubule-severing enzymes and the movement of molecular motors through their boundaries. We propose that reversible self-association of tau molecules, gated by the microtubule lattice, is an important mechanism of the biological functions of tau, and that oligomerization of tau is a common property shared between the physiological and disease-associated forms of the molecule

Optical Demonstration of THz, Dual-Polarization Sensitive Microwave Kinetic Inductance Detectors

The next generation BLAST experiment (BLAST-TNG) is a suborbital balloon payload that seeks to map polarized dust emission in the 250 $\mu$m, 350 $\mu$m and 500 $\mu$m wavebands. The instrument utilizes a stepped half-wave plate to reduce systematics. The general requirement of the detectors is that they are photon-noise-limited and dual-polarization sensitive. To achieve this goal, we are developing three monolithic arrays of cryogenic sensors, one for each waveband. Each array is feedhorn-coupled and each spatial pixel consists of two orthogonally spaced polarization-sensitive microwave kinetic inductance detectors (MKIDs) fabricated from a Ti/TiN multilayer film. In previous work, we demonstrated photon-noise-limited sensitivity in 250 $\mu$m waveband single polarization devices. In this work, we present the first results of dual-polarization sensitive MKIDs at 250 $\mu$m.Comment: 7 pages, 4 figures, published by JLT

From the cell membrane to the nucleus: unearthing transport mechanisms for Dynein

Mutations in the motor protein cytoplasmic dynein have been found to cause Charcot-Marie-Tooth disease, spinal muscular atrophy, and severe intellectual disabilities in humans. In mouse models, neurodegeneration is observed. We sought to develop a novel model which could incorporate the effects of mutations on distance travelled and velocity. A mechanical model for the dynein mediated transport of endosomes is derived from first principles and solved numerically. The effects of variations in model parameter values are analysed to find those that have a significant impact on velocity and distance travelled. The model successfully describes the processivity of dynein and matches qualitatively the velocity profiles observed in experiments

The Career Path and Profile of Women Chief Academic Officers in Public Community Colleges

"...it would appear that for women a variety of credentials and experiences have become the medium of exchange." The position of chief academic officer (CAO) is complex and demanding. The holders of this office are generally recognized as the highest-ranking academic administrator of their institution and are charged with directing its academic mission. They are looked to for leadership, vision, and wisdom. This position is also the one most commonly held prior to assuming a presidency of an institution of higher education (Plotts, 1998; Ross & Green, 1998; Twombly, 1986). Vaughan (1989) reported that 50% of the presidents in community colleges held the CAO position immediately prior to the presidency. Twombly (1988) also confirms the importance of the CAO position in the career path leading to the community college presidency. Given their impact on the academic programs of their institutions and the likelihood that they will advance to the presidency, investigations into the career paths of these academic professionals are warranted