714 research outputs found
Control of a Circular Jet
The present study report direct numerical simulation (DNS) of a circular jet
and the effect of a large scale perturbation at the jet inlet. The perturbation
is used to control the jet for increased spreading. Dual-mode perturbation is
obtained by combining an axisymmetric excitation with the helical. In the fluid
dynamics videos, an active control of the circular jet at a Reynolds number of
2000 for various frequency ratios (both integer and non-integer) has been
demonstrated. When the frequency ratio is fixed to 2, bifurcation of the jet on
a plane is evident. However, for a non-integer frequency ratio, the
axisymmetric jet is seen to bloom in all directions.Comment: 2 page
Finite-size corrections for confined polymers in the extended de Gennes regime
Theoretical results for the extension of a polymer confined to a channel are
usually derived in the limit of infinite contour length. But experimental
studies and simulations of DNA molecules confined to nanochannels are not
necessarily in this asymptotic limit. We calculate the statistics of the span
and the end-to-end distance of a semiflexible polymer of finite length in the
extended de Gennes regime, exploiting the fact that the problem can be mapped
to a one-dimensional weakly self-avoiding random walk. The results thus
obtained compare favourably with pruned-enriched Rosenbluth method (PERM)
simulations of a three-dimensional discrete wormlike chain model of DNA
confined in a nanochannel. We discuss the implications for experimental studies
of linear -DNA confined to nanochannels at the high ionic strengths
used in many experiments
Hairpins in the conformations of a confined polymer
If a semiflexible polymer confined to a narrow channel bends around by 180
degrees, the polymer is said to exhibit a hairpin. The equilibrium extension
statistics of the confined polymer are well understood when hairpins are
vanishingly rare or when they are plentiful. Here we analyze the extension
statistics in the intermediate situation via experiments with DNA coated by the
protein RecA, which enhances the stiffness of the DNA molecule by approximately
one order of magnitude. We find that the extension distribution is highly
non-Gaussian, in good agreement with Monte Carlo simulations of confined
discrete wormlike chains. We develop a simple model that qualitatively explains
the form of the extension distribution. The model shows that the tail of the
distribution at short extensions is determined by conformations with one
hairpin.Comment: Revised version. 22 pages, 7 figures, 2 tables, supplementary
materia
YBCO-buffered NdBCO film with higher thermal stability in seeding REBCO Growth
In this work, we report a strengthened superheating effect caused by a
buffering YBa2Cu3Oy (Y123 or YBCO) layer in the Nd1+xBa2-xCu3O7-y (Nd123 or
NdBCO) thin film with MgO substrate (i.e., NdBCO/YBCO/MgO thin film). In the
cold-seeding melt-textured (MT) growth, the NdBCO/YBCO/MgO film presented an
even higher superheating level, about 20 {\deg}C higher than that of
non-buffered NdBCO film (i.e., NdBCO/MgO film). Using this NdBCO/YBCO/MgO film
as seeds and undergoing a maximum processing temperature (Tmax) up to 1120
{\deg}C, we succeeded in growing various RE1+xBa2-xCu3O7-y (REBCO, RE=rare
elements) bulk superconductors, including Gd1+xBa2-xCu3O7-y (GdBCO),
Sm1+xBa2-xCu3O7-y (SmBCO) and NdBCO that have high peritectic temperatures
(Tp). The pole figure (X-Ray \phi-scan) measurement reveals that the
NdBCO/YBCO/MgO film has better in-plane alignment than the NdBCO/MgO film,
indicating that the induced intermediate layer improves the crystallinity of
the NdBCO film, which could be the main origin of the enhanced thermal
stability. In short, possessing higher thermal stability and enduring a higher
Tmax in the MT process, the NdBCO/YBCO/MgO film is beneficial to the growth of
bulk superconductors in two aspects: (1) broad application for high-Tp REBCO
materials; (2) effective suppression against heterogeneous nucleation, which is
of great assistance in growing large and high-performance REBCO crystals.Comment: 9 pages, 4 figure
Cervical traction: a simple step ahead in the prevention of postpartum hemorrhage
Background: Postpartum hemorrhage is the most common preventable cause of maternal mortality in developing countries. The present study aimed to examine the impact of cervical traction technique in reducing the amount of postpartum blood loss and rate of PPH.Methods: This was a case-control, pilot study conducted in a tertiary hospital between June 2017 to June 2018. A total of 200 singletons, low-risk pregnant females, undergoing normal vaginal delivery, were enrolled in this study. Subjects showing a high risk for PPH were excluded. Patients were randomized as case group (n=100) and control group (n=100). The case group received sustained traction for 90 seconds to anterior and posterior lip of the cervix with active management of the third stage of labor, whereas the control group received routine active management of the third stage of labor. All subjects were followed up for 6 hours post-delivery. The amount of blood loss, hematocrit and hemoglobin post-delivery were compared between both groups.Results: The mean blood loss (ml), decrease in hemoglobin (g/L) and decrease in hematocrit post-delivery in cases were significantly low compared to controls (207±37.6 versus 340±49, P<0.01), (0.78±0.2 versus 1.4±0.3, P=0.03) and (1.7±0.2 versus 3.5±0.2, P<0.01). PPH occurred in 7 of 200 (3.5%) patients. The difference in the number of PPH was not significant (5/100; 5% versus 2/100; 2% P=0.2). There were no complications reported due to cervical traction.Conclusions: Cervical traction is a simple and safe maneuver to reduce the amount of postpartum blood loss. Larger RCT is recommended to investigate the reduction in PPH rate
Determining Material Response for Polyvinyl Butyral (PVB) in Blast Loading Situations
Protecting structures from the effect of blast loads requires the careful design of all building components. In this context, the mechanical properties of Polyvinyl Butyral (PVB) are of interest to designers as the membrane behaviour will affect the performance of laminated glass glazing when loaded by explosion pressure waves. This polymer behaves in a complex manner and is difficult to model over the wide range of strain rates relevant to blast analysis. In this study, data from experimental tests conducted at strain rates from 0.01 s−1 to 400 s−1 were used to develop material models accounting for the rate dependency of the material. Firstly, two models were derived assuming Prony series formulations. A reduced polynomial spring and a spring derived from the model proposed by Hoo Fatt and Ouyang were used. Two fits were produced for each of these models, one for low rate cases, up to 8 s−1, and one for high rate cases, from 20 s−1. Afterwards, a single model representing all rates was produced using a finite deformation viscoelastic model. This assumed two hyperelastic springs in parallel, one of which was in series with a non-linear damper. The results were compared with the experimental results, assessing the quality of the fits in the strain range of interest for blast loading situations. This should provide designers with the information to choose between the available models depending on their design needs
Outcome of distal femoral fractures treated with locking compression plates
Background: Fixation of distal femoral fractures with a lateral plate alone is associated with nonunion and/or malunion with varus collapse. Locking compression plates may reduce the tendency of varus collapse. Hence, we evaluated the union rates and functional and anatomical outcome in patients of distal femoral fractures who were treated with locking compression plates.Methods: This prospective study was conducted at a tertiary health care center at Bangalore between July 2010 and June 2012. Patients with distal femoral fractures were treated with locking compression plates and were followed up for at least 6 months. Outcomes were evaluated using Neer’s score to assess outcomes in adult distal femoral fractures.Results: The study included 22 patients (10 males and 11 females) among whom one patient was lost to follow up within 6 months after the procedure. All the fractures were post-traumatic. Nineteen (91%) patients had closed fractures whereas two (9%) had open fractures. Muller’s A1 type was the most common (n=7) type of fracture followed by C2, C1, A2 (n=4 each) and B1, A3 (n= 1 each). Median duration of follow-up was 8 months (range: 6-18 months). The mean NEER’s functional score was 80 points. Overall results were excellent in 5 (24%) out of 21 cases and were satisfactory in 15 (71%) cases and only one had an unsatisfactory result.Conclusions: Locking compression plates offer excellent-satisfactory outcome in patients with distal femoral fractures.
Surgical management of proximal tibial fractures with locking compression plate
Background: Incidence of proximal tibial fractures is increasing due to increasing incidence of road traffic accidents (RTA). Knee joint being one of the major weight bearing joint of the body, appropriate management of fracture around it will be of paramount importance in maintaining mobility. The recent development of locking compression plate (LCP) has revolutionized the treatment of proximal tibial fractures by overcoming the few drawbacks of conventional buttress plate.Methods: We studied 30 patients involving proximal tibial fracture manged using LCP [23 patients with minimally invasive plate osteosynthesis, (MIPO) technique and 7 patients with Open reduction and internal fixation (ORIF) technique]. We followed up all the patients until complete union of fractures.Results: The average time for union of fracture was 14 weeks (range: 12-24 weeks). Overall 96.7% patients had acceptable outcome (70% excellent and 26.7% good). Patients treated with MIPO technique healed earlier and more frequently had excellent results than those treated with ORIF. A total of four patients had complications (knee joint stiffness in 1, postoperative loss of reduction in 1, infection in 1 and knee instability in 1). Conclusions: Locking compression plate system acts as a good biological fixation for proximal tibial fractures even in difficult fracture situations. MIPO technique offers faster healing and better outcome than ORIF in patients with proximal tibial fractures
Ayurvedic approach in the functional improvement of Systemic Lupus Erythematosus (SLE) - A Case Report
Systemic lupus erythematosus (SLE) is an auto immune disease in which organs and cells undergo damage mediated by tissue-binding autoantibodies and immune complex.[1]. 90% of patients are women of child-bearing years are affected with this disease. According to Ayurveda, the signs and symptoms can be included under the purview of Vataraktha. Case summary: A 43-year-old female patient approached with chief complaints of pain over bilateral elbow joints, shoulder joints and low back pain, burning sensation over toes for 8 years associated with febrile attacks, coated tongue, mouth ulcer, dryness of mouth aggravated since 2 months. The Ayurvedic diagnosis was made as Vataraktha on the basis of signs and symptoms. The patient was given Sadyovirechana (Purgation therapy), Basti therapy (enema) along with other external procedures and internal medications. Significant improvement was observed after the treatment in terms of VAS Score and other subjective parameters. This case study shows that Ayurvedic treatment is helpful in the functional improvement of SLE and helps in improving the quality of life
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