Innovation and design change strategies for learning technologies at Warwick : towards a ‘design capabilities’ heuristic for guiding practice and evaluating change.

This report gives a narrative account of an investigation into design and design capability in teaching and learning in a research-intensive university. It begins, in the Introduction, with definitions of key concepts: design, designing, successful design (achieving fit, stick, spread and growth), design change and design capability (although this last term is only really fleshed­out in Reading the Case Studies and the Conclusion). These words are common currency, but rarely used with precision. When clearly defined they provide a lens through which we can attain more clarity and granularity in analysing attempts at enhancing practice. In the second part, on the Origins of the Investigation and Earlier Experiments, we examine the limitations of a techno­centric approach to understanding, predicting and supporting the uptake of technology enhanced learning. It is argued that a design capability approach is needed, in which the ability of all people (including students) to discover, create, adopt, adapt designs that fit, stick, spread and grow is of prime value. In part 3, the design of the investigation is explained, with its focus upon discovering, creating and using design patterns as a key facilitating aspect of design capability. In part 4, this is put to the test, with an attempt at creatively reading the 23 mini case studies produced in interviews with academics. However, design patterns do not emerge easily from the cases, and we see that design and designing in this setting is more diverse and complex than expected. It is argued that a design patterns based approach will be useful, but much more work needs to be done before design patterns can become the lingua franca of teaching and learning design and development. This leads to a more sophisticated view of design capability, presented in the Conclusion. Drawing upon the experiences of the academics interviewed in the case studies, especially experienced and confident senior academics, it is conjectured that we need to increase the intensity with which academics encounter and reflect upon design challenges, designerly approaches, suboptimal and successful designs and design patterns. An integrated combination of Design Thinking and the Higher Education Academy Fellowship framework is recommended as a way of achieving this

Flipping the classroom : a design study of the adoption and adaption of new pedagogy in a higher education context

The Flipped Classroom idea is simple: the students consume lecture content as videos or audios individually in their own time, freeing­-up lecture time for more interactive and constructive pedagogies, with the students being more engaged and active in class. Does this fit with the Higher Education context? Specifically anywhere in Warwick (a research-intensive university in the English Midlands)? This paper reports on the initial phase of a Design Thinking investigation inspired by the basic Flipped Classroom idea, looking for ways in which it may be adopted and/or adapted to fit into existing or changing HE practices, in specific well defined contexts. In doing so, important lessons are learned concerning the diversity and specificity of the disciplines that are considered (english literature, medicine, psychology, teacher training, history, chemistry). The cases presented in the 7 design studies each illustrates how an academic teacher has designed new practice to address problems encountered in teaching, by applying pedagogy that stands out from the everyday pedagogies of their disciplines. They show how designerly practitioners can reflect upon teaching, identify "threshold concepts" and areas of difficulty (or even liminality), and respond with additional design and development work

Pedagogical strategies and technologies for peer assessment in Massively Open Online Courses (MOOCs)

Peer assessment has been mooted as an effective strategy for scaling­-up higher education and its core values to the proportions envisaged in the idea of Massively Open Online Courses (MOOCs). If this is to become reality, what role will academic technologies play? What technologies will we need to provide? What learning design strategies and patterns will those technologies need to enable? This paper aims to explore the potential role of peer assessment in MOOCs, so as to get an informed sense of technology requirements. However, as will be seen, three of the four elements in the title “pedagogical strategies and technologies for peer assessment in MOOCs” vary radically for both practical and philosophical reasons, with significant implications for technology requirements. Worse still, the picture is evolving in non­linear relation to new technologies and MOOC initiatives. An overview of the various trends and differences is useful, but not conclusive. At points in the text learning design strategies, patterns and technologies are mentioned as possible ways in which peer assessment in MOOCs of various kinds might be implemented. These cases are highlighted in bold so as to stand out. They are also, in some cases, developed into simple design patterns, described in Appendix A. It should be noted, however, that they should be read within the wider pedagogical contexts within which they appear in the main body of the text

A report on e-portfolios : design features, uses, benefits, examples & emerging trends

This paper gives a more sophisticated response to the rapid (re)emergence of the e­portfolio buzz­word. Starting from a basic e­portfolio design pattern, a wide range of variations are explored. The aim is to establish a body of knowledge for guiding users and technology providers, so as to achieve an ever­more appropriate and fruitful alignment of needs, designs, platforms and informed choices. The key benefits of e­portfolio approaches are discussed, with some coverage of the variations, and suggested research and development directions. Deep and persistent diversity­creating factors are highlighted. A range of mini case studies from Warwick are then examined to throw further light upon the combinations of real and perceived needs, platform affordances and design choices. Finally, this is a fast evolving field, especially given the near ­ubiquitous adoption of platforms with e­portfolio­like elements (Facebook, LinkedIn etc). Technology and academic support services must look further forwards to emerging practices and requirements just at the edge of the institutional­perceptual horizon. We must be prepared to shape these potentially disruptive developments for the benefit of students, teachers, the institution and society

Evidence for a planetary mass third body orbiting the binary star KIC 5095269

In this paper, we report the evidence for a planetary mass body orbiting the close binary star KIC 5095269. This detection arose from a search for eclipse timing variations among the more than 2,000 eclipsing binaries observed by Kepler. Light curve and periodic eclipse time variations have been analysed using Systemic and a custom Binary Eclipse Timings code based on the Transit Analysis Package which indicates a $7.70\pm0.08M_{Jup}$ object orbiting every $237.7\pm0.1d$ around a $1.2M_\odot$ primary and $0.51M_\odot$ secondary in an 18.6d orbit. A dynamical integration over $10^7$ years suggests a stable orbital configuration. Radial velocity observations are recommended to confirm the properties of the binary star components and the planetary mass of the companion.Comment: 8 pages, 7 figures, Accepted for publication in MNRA

The MultiSite Spectroscopic Telescope campaign: 2m spectroscopy of the V361 Hya variable PG1605+072

We present results and analysis for the 2m spectroscopic part of the MultiSite Spectroscopic Telescope (MSST) campaign undertaken in May/June 2002. The goal of the project was to observe the pulsating subdwarf B star PG1605+072 simultaneously in velocity and photometry and to resolve as many of the >50 known modes as possible, which will allow a detailed asteroseismological analysis. We have obtained over 150 hours of spectroscopy, leading to an unprecedented noise level of only 207m/s. We report here the detection of 20 frequencies in velocity, with two more likely just below our detection threshold. In particular, we detect 6 linear combinations, making PG1605+072 only the second star known to show such frequencies in velocity. We investigate the phases of these combinations and their parent modes and find relationships between them that cannot be easily understood based on current theory. These observations, when combined with our simultaneous photometry, should allow asteroseismology of this most complicated of sdB pulsators.Comment: 9 pages, 5 figures, accepted for publication in A&A; Figure 1 at lower resolution than accepted versio

Lactobacillus ruminis strains cluster according to their mammalian gut source

peer-reviewedBackground Lactobacillus ruminis is a motile Lactobacillus that is autochthonous to the human gut, and which may also be isolated from other mammals. Detailed characterization of L. ruminis has previously been restricted to strains of human and bovine origin. We therefore sought to expand our bio-bank of strains to identify and characterise isolates of porcine and equine origin by comparative genomics. Results We isolated five strains from the faeces of horses and two strains from pigs, and compared their motility, biochemistry and genetic relatedness to six human isolates and three bovine isolates including the type strain 27780T. Multilocus sequence typing analysis based on concatenated sequence data for six individual loci separated the 16 L. ruminis strains into three clades concordant with human, bovine or porcine, and equine sources. Sequencing the genomes of four additional strains of human, bovine, equine and porcine origin revealed a high level of genome synteny, independent of the source animal. Analysis of carbohydrate utilization, stress survival and technological robustness in a combined panel of sixteen L. ruminis isolates identified strains with optimal survival characteristics suitable for future investigation as candidate probiotics. Under laboratory conditions, six human isolates of L. ruminis tested were aflagellate and non-motile, whereas all 10 strains of bovine, equine and porcine origin were motile. Interestingly the equine and porcine strains were hyper-flagellated compared to bovine isolates, and this hyper-flagellate phenotype correlated with the ability to swarm on solid medium containing up to 1.8% agar. Analysis by RNA sequencing and qRT-PCR identified genes for the biosynthesis of flagella, genes for carbohydrate metabolism and genes of unknown function that were differentially expressed in swarming cells of an equine isolate of L. ruminis. Conclusions We suggest that Lactobacillus ruminis isolates have potential to be used in the functional food industry. We have also identified a MLST scheme able to distinguish between strains of L. ruminis of different origin. Genes for non-digestible oligosaccharide metabolism were identified with a putative role in swarming behaviour.This work was supported by a Principal Investigator Award (07/IN.1/B1780) from Science Foundation Ireland to P.W. O’Toole

Phylogenomics and comparative genomics of Lactobacillus salivarius, a mammalian gut commensal

The genus Lactobacillus is a diverse group with a combined species count of over 200. They are the largest group within the lactic acid bacteria and one of the most important bacterial groups involved in food microbiology and human nutrition because of their fermentative and probiotic properties. Lactobacillus salivarius, a species commonly isolated from the gastrointestinal tract of humans and animals, has been described as having potential probiotic properties and results of previous studies have revealed considerable functional diversity existing on both the chromosomes and plasmids. Our study consists of comparative genomic analyses of the functional and phylogenomic diversity of 42 genomes of strains of L . salivarius using bioinformatic techniques. The main aim of the study was to describe intra-species diversity and to determine how this diversity is spread across the replicons. We found that multiple phylogenomic and non-phylogenomic methods used for reconstructing trees all converge on similar tree topologies, showing that different metrics largely agree on the evolutionary history of the species. The greatest genomic variation lies on the small plasmids, followed by the repA-type circular megaplasmid, with the chromosome varying least of all. Additionally, the presence of extra linear and circular megaplasmids is noted in several strains, while small plasmids are not always present. Glycosyl hydrolases, bacteriocins and proteases vary considerably on all replicons while two exopolysaccharide clusters and several clustered regularly interspaced short palindromic repeats-associated systems show a lot of variation on the chromosome. Overall, despite its reputation as a mammalian gastrointestinal tract specialist, the intra-specific variation of L. salivarius reveals potential strain-dependant effects on human health