381 research outputs found

    A new differential configuration suitable for realization of high CMRR, all-pass/notch filters

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    #yayıncısurumuyok# ; Tam metin hakemden geçmiş kopyadır.In this paper, a new configuration suitable for realization of differential input-differential output first order, second order all-pass and notch filters with high CMRR is given. The proposed configuration uses two negative type second-generation current conveyors (CCII-), and three admittances. Two first order and one second order all-pass filters and a notch filter (tunable if current controlled conveyor CCCII is used) are extracted from the proposed configuration. Tracking error, element mismatch, sensitivity analysis, simulation and experimental results are included

    Automated detection of e-scooter helmet use with deep learning

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    E-scooter riders have an increased crash risk compared to cyclists [1 ]. Hospital data finds increasing numbers of injured e-scooter riders, with head injuries as one of the most common injury types [2]. To decrease this high prevalence of head injuries, the use of e-scooter helmets could present a potential countermeasure [3]. Despite this, studies show a generally low rate of helmet use rates in countries without mandatory helmet use laws [4][5][6]. In countries with mandatory helmet use laws for e-scooter riders, helmet use rates are higher, but generally remain lower than bicycle use rates [7]. As the helmet use rate is a central factor for the safety of e-scooter riders in case of a crash and a key performance indicator in the European Commission's Road Safety Policy Framework 2021-2030 [8], efficient e-Scooter helmet use data collection methods are needed. However, currently, human observers are used to register e-scooter helmet use either in direct roadside observations or in indirect video-based observation, which is time-consuming and costly. In this study, a deep learning-based method for the automated detection of e-scooter helmet use in video data was developed and tested, with the aim to provide an efficient data collection tool for road safety researchers and practitioners

    A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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    Meeting abstrac

    Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

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    Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

    Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

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    This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

    High Efficiency Wideband Power Amplifier with Class-J Configuration

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    18th Mediterranean Microwave Symposium (MMS) -- OCT 31-NOV 02, 2018 -- Istanbul, TURKEYThe design and implementation of a high efficiency Class-J mode RF power amplifier (PA) for wireless communications applications is described here. In this study, a broadband class-J power amplifier with GaN HEMT transistor is designed to achieve 40 dBm output power and 10 dB gain, high efficiency and linearity performance in the 2.5-3.5 GHz frequency band. Experimental results indicate good agreement with simulations verifying and demonstrating the class-J mode operation. The obtained power added efficiency (PAE) is above 68% and the output power is 39.84 dBm at an input drive of 30 dBm. High efficiency is achieved in the frequency range from 2.5 GHz to 3.5 GHz. Simulation and experimental results show that the class-J RF power amplifier can be realized more effectively in terms of a better compromise between power and efficiency trade-offs over a significant RF bandwidth than conventional class-AB/B operations. the ACPR value for the linearity measurement was found to be around -30 dBc

    Partial Depth Precast Concrete Deck Panels on Curved Bridges: Finite Element Analytical Model of PCPs

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    Report on partial depth precast concrete deck panels on curved bridges

    Impact of the COVID-19 Pandemic on Breast Cancer Mortality in the US: Estimates From Collaborative Simulation Modeling

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    BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has disrupted breast cancer control through short-term declines in screening and delays in diagnosis and treatments. We projected the impact of COVID-19 on future breast cancer mortality between 2020 and 2030. METHODS: Three established Cancer Intervention and Surveillance Modeling Network breast cancer models modeled reductions in mammography screening use, delays in symptomatic cancer diagnosis, and reduced use of chemotherapy for women with early-stage disease for the first 6 months of the pandemic with return to prepandemic patterns after that time. Sensitivity analyses were performed to determine the effect of key model parameters, including the duration of the pandemic impact. RESULTS: By 2030, the models project 950 (model range = 860-1297) cumulative excess breast cancer deaths related to reduced screening, 1314 (model range = 266-1325) associated with delayed diagnosis of symptomatic cases, and 151 (model range = 146-207) associated with reduced chemotherapy use in women with hormone positive, early-stage cancer. Jointly, 2487 (model range = 1713-2575) excess breast cancer deaths were estimated, representing a 0.52% (model range = 0.36%-0.56%) cumulative increase over breast cancer deaths expected by 2030 in the absence of the pandemic's disruptions. Sensitivity analyses indicated that the breast cancer mortality impact would be approximately double if the modeled pandemic effects on screening, symptomatic diagnosis, and chemotherapy extended for 12 months. CONCLUSIONS: Initial pandemic-related disruptions in breast cancer care will have a small long-term cumulative impact on breast cancer mortality. Continued efforts to ensure prompt return to screening and minimize delays in evaluation of symptomatic women can largely mitigate the effects of the initial pandemic-associated disruptions

    Breast Cancer Screening Using Mammography, Digital Breast Tomosynthesis, and Magnetic Resonance Imaging by Breast Density

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    Importance: Information on long-term benefits and harms of screening with digital breast tomosynthesis (DBT) with or without supplemental breast magnetic resonance imaging (MRI) is needed for clinical and policy discussions, particularly for patients with dense breasts. Objective: To project long-term population-based outcomes for breast cancer mammography screening strategies (DBT or digital mammography) with or without supplemental MRI by breast density. Design, Setting, and Participants: Collaborative modeling using 3 Cancer Intervention and Surveillance Modeling Network (CISNET) breast cancer simulation models informed by US Breast Cancer Surveillance Consortium data. Simulated women born in 1980 with average breast cancer risk were included. Modeling analyses were conducted from January 2020 to December 2023. Intervention: Annual or biennial mammography screening with or without supplemental MRI by breast density starting at ages 40, 45, or 50 years through age 74 years. Main outcomes and Measures: Lifetime breast cancer deaths averted, false-positive recall and false-positive biopsy recommendations per 1000 simulated women followed-up from age 40 years to death summarized as means and ranges across models. Results: Biennial DBT screening for all simulated women started at age 50 vs 40 years averted 7.4 vs 8.5 breast cancer deaths, respectively, and led to 884 vs 1392 false-positive recalls and 151 vs 221 false-positive biopsy recommendations, respectively. Biennial digital mammography had similar deaths averted and slightly more false-positive test results than DBT screening. Adding MRI for women with extremely dense breasts to biennial DBT screening for women aged 50 to 74 years increased deaths averted (7.6 vs 7.4), false-positive recalls (919 vs 884), and false-positive biopsy recommendations (180 vs 151). Extending supplemental MRI to women with heterogeneously or extremely dense breasts further increased deaths averted (8.0 vs 7.4), false-positive recalls (1088 vs 884), and false-positive biopsy recommendations (343 vs 151). The same strategy for women aged 40 to 74 years averted 9.5 deaths but led to 1850 false-positive recalls and 628 false-positive biopsy recommendations. Annual screening modestly increased estimated deaths averted but markedly increased estimated false-positive results. Conclusions and relevance: In this model-based comparative effectiveness analysis, supplemental MRI for women with dense breasts added to DBT screening led to greater benefits and increased harms. The balance of this trade-off for supplemental MRI use was more favorable when MRI was targeted to women with extremely dense breasts who comprise approximately 10% of the population.</p
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