553 research outputs found

    Between a rock and a hard place: corporate elites in the context of religion and secularism in Turkey

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    Drawing on discourse analyses of 36 in-depth interviews with elite business people from Turkey, the study identifies the networking patterns of new and established business elites in the context of economic liberalization and socioreligious transformation of the country. Through a comparative analysis of the so-called secular and religious elite networks, we demonstrate the role of institutional actors such as the government, and identity networks, based on religion and place of birth in shaping the form and content of social networks among business elites in Turkey. In order to achieve this, we operationalize Bourdieu's notion of theory of practice and Granovetter's theory of social networks, illustrating the utility of combining these approaches in explicating the form and content of social networks in their situated contexts, in which power and divergent interests are negotiated.Galatasaray University Research Fund [grant number 12.102.005]

    Lymphocyte subsets and the role of Th1/Th2 balance in stressed chronic pain patients

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    Background: The complex regional pain syndrome (CRPS) and fibromyalgia (FM) are chronic pain syndromes occurring in highly stressed individuals. Despite the known connection between the nervous system and immune cells, information on distribution of lymphocyte subsets under stress and pain conditions is limited. Methods: We performed a comparative study in 15 patients with CRPS type I, 22 patients with FM and 37 age- and sex-matched healthy controls and investigated the influence of pain and stress on lymphocyte number, subpopulations and the Th1/Th2 cytokine ratio in T lymphocytes. Results: Lymphocyte numbers did not differ between groups. Quantitative analyses of lymphocyte subpopulations showed a significant reduction of cytotoxic CD8+ lymphocytes in both CRPS (p < 0.01) and FM (p < 0.05) patients as compared with healthy controls. Additionally, CRPS patients were characterized by a lower percentage of IL-2-producing T cell subpopulations reflecting a diminished Th1 response in contrast to no changes in the Th2 cytokine profile. Conclusions: Future studies are warranted to answer whether such immunological changes play a pathogenetic role in CRPS and FM or merely reflect the consequences of a pain-induced neurohumoral stress response, and whether they contribute to immunosuppression in stressed chronic pain patients. Copyright (c) 2008 S. Karger AG, Basel

    The prevalence of giant cell arteritis and polymyalgia rheumatica in a UK primary care population

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    Background: To update community-based prevalence values for Polymyalgia Rheumatic (PMR) and Giant Cell Arteritis (GCA) using case record review supplemented by population survey and subsequent clinical review. Methods: Clinical data were obtained from case records of a large primary care practice in Norfolk, UK and reviewed for diagnoses of GCA and PMR. In addition postal survey was carried out to capture potentially undiagnosed cases within the practice population. Those screening positive for potential diagnoses of GCA and PMR were invited for clinical review. A cumulative prevalence estimate was subsequently calculated on those diagnosed within the GP practice and subsequently on those fulfilling the various published classification criteria sets. The date of the database lock and mail merge was March 2013. Results: Through detailed systematic review of 5,159 GP case records, 21 patients had a recorded diagnosis of GCA and 117 had PMR . No new cases were identified among 2,227 completed questionnaires returned from the population survey of a sample of 4,728. The resulting cumulative prevalence estimate in those aged ≥55 years meeting the ACR classification criteria set for GCA was 0.25% (95% CI 0.11% to 0.39%) and for five published criteria sets for PMR ranged from 0.91% to 1.53% (95% CI ranges 0.65%, 1.87%). The prevalence of both conditions was higher in women than in men and in older age groups. Conclusion: This study provides the first UK prevalence estimate of GCA and PMR in over 30 years and is the first to apply classification criteria sets

    Insights into the structure of liquid water from nuclear quantum effects on density and compressibility of ice polymorphs

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    Nuclear quantum effects lead to an anomalous shift of the volume of hexagonal ice; heavy ice has a larger volume than light ice. This anomaly in ice increases with temperature and persists in liquid water up to the boiling point. We study nuclear quantum effects on the density and compressibility of several ice-like structures and crystalline ice phases. By calculating the anisotropic contributions to the stain tensor, we analyze how the compressibility changes along different directions in hexagonal ice, and find that hexagonal ice is softer along the x-y plane than the z-direction. Furthermore, by performing ab initio density functional theory calculations with a van der Waals functional and with the quasiharmonic approximation, we find an anomalous isotope effect in the bulk modulus of hexagonal ice: heavy ice has a smaller bulk modulus than light ice. In agreement with the experiments, we also obtain an anomalous isotope effect for clathrate hydrate structure I. For the rest of the ice polymorphs, the isotope effect is: i) anomalous for ice IX, Ih, Ic, clathrate, and low density liquid-like amorphous ice; ii) normal at T=0 K and becomes anomalous with increasing temperature for ice IX, II, high density liquid-like amorphous ices, and ice XV; iii) normal for ice VIII up to the melting point. There is a transition from an anomalous isotope effect to a normal isotope effect for both the volume and bulk modulus, as the density (compressibility) of the structures increases (decreases). This result can explain the anomalous isotope effect in liquid water: as the compressibility decreases from melting point to the compressibility minimum temperature, the difference between the volumes of the heavy and light water rapidly decreases, but the effect stays anomalous up to the boiling temperature as the hydrogen bond network is never completely broken by fully filling all the interstitial sites.Comment: 17 pages, 15 figure

    Different paths to the modern state in Europe: the interaction between domestic political economy and interstate competition

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    Theoretical work on state formation and capacity has focused mostly on early modern Europe and on the experience of western European states during this period. While a number of European states monopolized domestic tax collection and achieved gains in state capacity during the early modern era, for others revenues stagnated or even declined, and these variations motivated alternative hypotheses for determinants of fiscal and state capacity. In this study we test the basic hypotheses in the existing literature making use of the large date set we have compiled for all of the leading states across the continent. We find strong empirical support for two prevailing threads in the literature, arguing respectively that interstate wars and changes in economic structure towards an urbanized economy had positive fiscal impact. Regarding the main point of contention in the theoretical literature, whether it was representative or authoritarian political regimes that facilitated the gains in fiscal capacity, we do not find conclusive evidence that one performed better than the other. Instead, the empirical evidence we have gathered lends supports to the hypothesis that when under pressure of war, the fiscal performance of representative regimes was better in the more urbanized-commercial economies and the fiscal performance of authoritarian regimes was better in rural-agrarian economie

    Anomalous Nuclear Quantum Effects in Ice

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    One striking anomaly of water ice has been largely neglected and never explained. Replacing hydrogen (1^1H) by deuterium (2^2H) causes ice to expand, whereas the "normal" isotope effect is volume contraction with increased mass. Furthermore, the anomaly increases with temperature TT, even though a normal isotope shift should decrease with TT and vanish when TT is high enough to use classical nuclear motions. In this study, we show that these effects are very well described by {\it ab initio} density functional theory. Our theoretical modeling explains these anomalies, and allows us to predict and to experimentally confirm a counter effect, namely that replacement of 16^{16}O by 18^{18}O causes a normal lattice contraction.Comment: 5 pages, 3 figure

    The Future Mortality of High Mortality Countries: A Model Incorporating Expert Arguments

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    This paper examines the future of mortality in the 65 countries still experiencing high mortality in 2010, as defined by a cutoff of 40 deaths before age five per thousand live births. Mortality declines in several countries stagnated or reversed in the last two decades of the twentieth century due mainly to HIV/AIDS. The forces underlying past mortality trends and affecting the future course of mortality are examined by reviewing the existing literature and reporting the results of the global survey and invited meeting, both involving mortality experts. The experts assessed the likelihood and weight of forces hypothesized to influence mortality. A statistical model is combined with these expert assessments to produce a set of mortality assumptions that are incorporated into the projections reported in this paper. This paper also addresses the limited availability of reliable data on age-specific mortality rates
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