2,306 research outputs found

    Information Literacy and the Undergraduate Curriculum

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    Aerospace systems pyrotechnic shock data /ground test and flight/. Volume 4 - Lockheed data and analyses Final report, Jun. 1968 - Mar. 1970

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    Compilation of shock loads on spacecraft structures produced by actuation of pyrotechnics and explosive devices - Vol.

    Oral Apolipoprotein A-I Mimetic D-4F Lowers HDL-Inflammatory Index in High-Risk Patients: A First-in-Human Multiple-Dose, Randomized Controlled Trial.

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    A single dose of the apolipoprotein (apo)A-I mimetic peptide D-4F rendered high-density lipoprotein (HDL) less inflammatory, motivating the first multiple-dose study. We aimed to assess safety/tolerability, pharmacokinetics, and pharmacodynamics of daily, orally administered D-4F. High-risk coronary heart disease (CHD) subjects added double-blinded placebo or D-4F to statin for 13 days, randomly assigned 1:3 to ascending cohorts of 100, 300, then 500 mg (n = 62; 46 men/16 women). D-4F was safe and well-tolerated. Mean ± SD plasma D-4F area under the curve (AUC, 0-8h) was 6.9 ± 5.7 ng/mL*h (100 mg), 22.7 ± 19.6 ng/mL*h (300 mg), and 104.0 ± 60.9 ng/mL*h (500 mg) among men, higher among women. Whereas placebo dropped HDL inflammatory index (HII) 28% 8 h postdose (range, 1.25-0.86), 300-500 mg D-4F effectively halved HII: 1.35-0.57 and 1.22-0.63, respectively (P \u3c 0.03 vs. placebo). Oral D-4F peptide dose predicted HII suppression, whereas plasma D-4F exposure was dissociated, suggesting plasma penetration is unnecessary. In conclusion, oral D-4F dosing rendered HDL less inflammatory, affirming oral D-4F as a potential therapy to improve HDL function

    Mn valence instability in La2/3Ca1/3MnO3 thin films

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    A Mn valence instability on La2/3Ca1/3MnO3 thin films, grown on LaAlO3 (001)substrates is observed by x-ray absorption spectroscopy at the Mn L-edge and O K-edge. As-grown samples, in situ annealed at 800 C in oxygen, exhibit a Curie temperature well below that of the bulk material. Upon air exposure a reduction of the saturation magnetization, MS, of the films is detected. Simultaneously a Mn2+ spectral signature develops, in addition to the expected Mn3+ and Mn4+ contributions, which increases with time. The similarity of the spectral results obtained by total electron yield and fluorescence yield spectroscopy indicates that the location of the Mn valence anomalies is not confined to a narrow surface region of the film, but can extend throughout the whole thickness of the sample. High temperature annealing at 1000 C in air, immediately after growth, improves the magnetic and transport properties of such films towards the bulk values and the Mn2+ signature in the spectra does not appear. The Mn valence is then stable even to prolonged air exposure. We propose a mechanism for the Mn2+ ions formation and discuss the importance of these observations with respect to previous findings and production of thin films devices.Comment: Double space, 21 pages, 6 figure

    Properties of continuous Fourier extension of the discrete cosine transform and its multidimensional generalization

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    A versatile method is described for the practical computation of the discrete Fourier transforms (DFT) of a continuous function g(t)g(t) given by its values gjg_{j} at the points of a uniform grid FNF_{N} generated by conjugacy classes of elements of finite adjoint order NN in the fundamental region FF of compact semisimple Lie groups. The present implementation of the method is for the groups SU(2), when FF is reduced to a one-dimensional segment, and for SU(2)×...×SU(2)SU(2)\times ... \times SU(2) in multidimensional cases. This simplest case turns out to result in a transform known as discrete cosine transform (DCT), which is often considered to be simply a specific type of the standard DFT. Here we show that the DCT is very different from the standard DFT when the properties of the continuous extensions of these two discrete transforms from the discrete grid points tj;j=0,1,...Nt_j; j=0,1, ... N to all points tFt \in F are considered. (A) Unlike the continuous extension of the DFT, the continuous extension of (the inverse) DCT, called CEDCT, closely approximates g(t)g(t) between the grid points tjt_j. (B) For increasing NN, the derivative of CEDCT converges to the derivative of g(t)g(t). And (C), for CEDCT the principle of locality is valid. Finally, we use the continuous extension of 2-dimensional DCT to illustrate its potential for interpolation, as well as for the data compression of 2D images.Comment: submitted to JMP on April 3, 2003; still waiting for the referee's Repor

    Exact Solution Methods for the kk-item Quadratic Knapsack Problem

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    The purpose of this paper is to solve the 0-1 kk-item quadratic knapsack problem (kQKP)(kQKP), a problem of maximizing a quadratic function subject to two linear constraints. We propose an exact method based on semidefinite optimization. The semidefinite relaxation used in our approach includes simple rank one constraints, which can be handled efficiently by interior point methods. Furthermore, we strengthen the relaxation by polyhedral constraints and obtain approximate solutions to this semidefinite problem by applying a bundle method. We review other exact solution methods and compare all these approaches by experimenting with instances of various sizes and densities.Comment: 12 page

    Generic 3D Representation via Pose Estimation and Matching

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    Though a large body of computer vision research has investigated developing generic semantic representations, efforts towards developing a similar representation for 3D has been limited. In this paper, we learn a generic 3D representation through solving a set of foundational proxy 3D tasks: object-centric camera pose estimation and wide baseline feature matching. Our method is based upon the premise that by providing supervision over a set of carefully selected foundational tasks, generalization to novel tasks and abstraction capabilities can be achieved. We empirically show that the internal representation of a multi-task ConvNet trained to solve the above core problems generalizes to novel 3D tasks (e.g., scene layout estimation, object pose estimation, surface normal estimation) without the need for fine-tuning and shows traits of abstraction abilities (e.g., cross-modality pose estimation). In the context of the core supervised tasks, we demonstrate our representation achieves state-of-the-art wide baseline feature matching results without requiring apriori rectification (unlike SIFT and the majority of learned features). We also show 6DOF camera pose estimation given a pair local image patches. The accuracy of both supervised tasks come comparable to humans. Finally, we contribute a large-scale dataset composed of object-centric street view scenes along with point correspondences and camera pose information, and conclude with a discussion on the learned representation and open research questions.Comment: Published in ECCV16. See the project website http://3drepresentation.stanford.edu/ and dataset website https://github.com/amir32002/3D_Street_Vie

    Explicit Lie-Poisson integration and the Euler equations

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    We give a wide class of Lie-Poisson systems for which explicit, Lie-Poisson integrators, preserving all Casimirs, can be constructed. The integrators are extremely simple. Examples are the rigid body, a moment truncation, and a new, fast algorithm for the sine-bracket truncation of the 2D Euler equations.Comment: 7 pages, compile with AMSTEX; 2 figures available from autho
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