Barbell back squat:How do resistance bands affect muscle activation and knee kinematics?

ObjectivesThis study aimed to determine whether looped resistance bands affect knee kinematics and lower body muscle activation during the barbell back squat.MethodsTwenty-six healthy participants (13 female, 13 male) calculated their one repetition maximum (RM) prior to data collection. Each participant performed three squats at both 80% and 40% 1RM wearing a light resistance band, an extra-heavy resistance band and no resistance band.Vicon 3D motion analysis cameras were used to collect the kinematic data, and Delsys Trigno Lab wireless electromyography (EMG) system was used to measure vastus medialis, vastus lateralis, gluteus maximus, gluteus medius and biceps femoris muscle activity. Peak knee flexion angle, peak knee valgus angle and maximum tibial rotation values were examined. Peak EMG values were also analysed after being normalised and expressed as a percentage of maximum voluntary contraction (MVC).ResultsGluteus maximus (GM) activity is significantly increased when a resistance band is used during squatting. However, squatting with a resistance band is detrimental to knee kinematics as it leads to an increase in knee valgus angle and maximum tibial rotation angle. A direct correlation is recorded between an increase in resistance and an increase in these two angles.ConclusionsSquatting with resistance bands is likely to increase the risk of knee injury. Coaches and clinicians who already implement this technique are advised to remove resistance band squats from training and rehabilitation programmes. Further research evaluating the long-term effects of using resistance bands during the barbell back squat should be considered

Mécanismes d'élimination de l'azote et du phosphore dans un chenal algal à haut rendement

Le devenir de l'azote(N) et du phosphore (P) a été étudié dans un chenal à haut rendement (CAHR) au cours de la période d'adaptation puis en phase stationnaire. En moyenne, la part de N total perdue atteint 34,5% du N admis en période d'adaptation et 24,5% en phase stationnaire tandis que la part assimilée par les algues atteint respectivement 32 et 43,5%. L'azote organique particulaire s'accumule dans le sédiment et subit une minéralisation lente pendant la phase d'adaptation puis rapide en phase stationnaire. Les pertes nettes en N dans le CAHR seraient dues à la sédimentation et à la volatilisation de NH3 en saison froide et seulement au dernier mécanisme, en saison chaude. Le bilan de l'azote ammoniacal en phase stationnaire montre que l'importance de la biomasse algale produite en saison chaude ne peut s'expliquer qu'en présence d'une minéralisation active du sédiment. Le taux de minéralisation est estimé à 12,4 kg N ha-1 j-1 en saison chaude contre 1,3 en saison froide. En moyenne, la part du P total perdue atteint 27% du P admis en période d'adaptation et 17,5% en phase stationnaire alors que la part assimilée par les algues atteint respectivement 25 et 17,5%. En phase stationnaire, l'élimination du P soluble dans le CAHR serait due à l'assimilation algale (54%) et à la précipitation chimique sous forme de sels de phosphates (46%).The fate of nitrogen (N) and phosphorus (P) was studied in a high-rate algal pond (HRAP) during the start-up period and under steady-state conditions. The HRAP was first used by Oswald and co-workers in Berkeley (California, USA) in the late 1950s for wastewater treatment with algae collection as a by-product for Single Cell Protein production. The HRAP consisted of a raceway shaped, shallow pond (less than 0.50 m deep) equipped with a continuous and gentle mixing device (paddle wheel) generally operated at 8 rpm. The paddle wheel is not used for aeration purposes.In this study, the HRAP is included in a wastewater treatment plant aimed at producing good quality effluent for agriculture reuse purposes. The treatment plant includes three components with the HRAP placed in the middle of the pond train. Up-stream, there is a two-phase anaerobic reactor (TAR) and downstream, two maturation ponds in series. Assigned removal tasks for the plant components are as follows: i) organic matter, suspended solids and helminth eggs for the TAR; ii) N and P for the HRAP; and iii) fecal coliforms for the two maturation ponds. The capacity of the plant is 1,500 inhabitants (70 m3/day), total hydraulic retention time is 8 days and the total occupied area is 1,500 m2 including walkways and other facilities. The plant was constructed in December 1996 and has been continuously operated since that time.The present paper focuses on the fate of N and P in the HRAP in order to evaluate its performance and to shed light on the mechanisms behind N and P removal, with the ultimate goal to improve surface and groundwater protection from pollution by wastewater nutrients. Under steady-state conditions and when we consider the soluble part of N and P taken up by the algal cells together with that lost (either by stripping or chemical precipitation), the total removal averaged 70% for N and 40% for P. Such important removal must be highlighted especially because the system relies on solar energy with no electromechanical aeration, is cheap to construct and easy to operate and maintain.To understand the mechanisms behind such a performance and also to gain experience for the process start-up and for rational operation and maintenance of future plants, an in-depth analysis on the fate of N and P was done based on the four-year follow up data. Total N losses reached an average of 34.5% in the start-up period and 24.5% under steady-state conditions, whereas N assimilated by the algae represented 32 and 43.5%, respectively. Particulate organic nitrogen (PON) accumulated in the bottom of the unit did undergo rapid mineralization under steady-state conditions. Mechanisms involved in N losses might be attributed to settling of PONr and, to much lesser extent, NH3 volatilization in the cold season, whereas the latter mechanism might occur primarily in the hot season. The rates of mineralization of HRAP sediment were estimated to be 12.4 and 1.3 kg of N ha-1 d-1 respectively for the hot and the cold season.On average, total P losses in the HRAP reach 27% in the start-up period and only 17.5 % under steady-state conditions, whereas algae assimilation represented 25 and 17.5% respectively. Under steady-state conditions, algae uptake (54%) and chemical precipitation (46%) were found to be the main mechanisms for P removal in the HRAP

Mandatory Pharmacy Residencies: One way to reduce medication errors

We read with disbelief about a newly graduated pharmacist dispensing 30 times the amount of injectable sodium bicarbonate intended, an error that led to a patient’s death.1 As clinicians, we wondered what clinical scenario might mandate the large amount of sodium bicarbonate dispensed—the answer was none. So why did the pharmacist dispense it? The answer is all too clear: With rare exceptions, institutional pharmacists nationwide are largely focused on dispensing. Postgraduate clinical training in the basic aspects of pharmacotherapy is scarce and not viewed as essential. Inadequate pharmacist training and a staffing shortage were suggested as contributing to the death of a six-day-old infant who received 10 times the prescribed dose of i.v. potassium chloride at a university hospital.2 These two sobering misadventures hint at a link between pharmacists’ clinical training and patient safety

A Dynamic Data-Driven Simulation Approach for Preventing Service Level Agreement Violations in Cloud Federation

The new possibility of accessing an infinite pool of computational resources at a drastically reduced price has made cloud computing popular. With the increase in its adoption and unpredictability of workload, cloud providers are faced with the problem of meeting their service level agreement (SLA) claims as demonstrated by large vendors such as Amazon and Google. Therefore, users of cloud resources are embracing the more promising cloud federation model to ensure service guarantees. Here, users have the option of selecting between multiple cloud providers and subsequently switching to a more reliable one in the event of a provider’s inability to meet its SLA. In this paper, we propose a novel dynamic data-driven architecture capable of realising resource provision in a cloud federation with minimal SLA violations. We exemplify the approach with the aid of case studies to demonstrate its feasibility. Keywords

Gamma-ray lines and neutrons from solar flares

The energy spectrum of accelerated protons and nuclei at the site of a limb flare was derived by a technique, using observations of the time dependent flux of high energy neutrons at the Earth. This energy spectrum is very similar to the energy spectra of 7 disk flares for which the accelerated particle spectra was previously derived using observations of 4 to 7 MeV to 2.223 MeV fluence ratios. The implied spectra for all of these flares are too steep to produce any significant amount of radiation from pi meson decay. It is suggested that the observed 10 MeV gamma rays from the flare are bremsstrahlung of relativistic electrons

Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries

Extremity and soft tissue injuries contribute significantly to inflammation and adverse in-hospital outcomes for trauma survivors; accordingly, we examined the complex association between clinical outcomes inflammatory responses in this setting using in silico tools. Two stringently propensity-matched, moderately/severely injured (Injury Severity Score > 16) patient sub-cohorts of ~30 patients each were derived retrospectively from a cohort of 472 blunt trauma survivors and segregated based on their degree of extremity injury severity (above or below 3 on the Abbreviated Injury Scale). Serial blood samples were analyzed for 31 plasma inflammatory mediators. In addition to standard statistical analyses, Dynamic Network Analysis (DyNA) and Principal Component Analysis (PCA) were used to model systemic inflammation following trauma. Patients in the severe extremity injury sub-cohort experienced longer intensive care unit length of stay (LOS), total LOS, and days on a mechanical ventilator, with higher Marshall Multiple Organ Dysfunction (MOD) Scores over the first 7 days post-injury as compared to the mild/moderate extremity injury sub-cohort. The higher severity cohort had statistically significant elevated lactate, base deficit, and creatine phosphokinase on first blood draw, along with significant changes in multiple circulating inflammatory mediators. DyNA pointed to a sustained role for type 17 immunity in both sub-cohorts, along with IFN-γ in the severe extremity injury group. DyNA network complexity increased over 7 days post-injury in the severe injury group, while generally decreasing over this same time period in the mild/moderate injury group. PCA suggested a more robust activation of multiple pathways in the severe extremity injury group as compared to the mild/moderate injury group. These studies thus point to the possibility of self-sustaining inflammation following severe extremity injury vs. resolving inflammation following less severe extremity injury

Flow angle from intermediate mass fragment measurements

Directed sideward flow of light charged particles and intermediate mass fragments was measured in different symmetric reactions at bombarding energies from 90 to 800 AMeV. The flow parameter is found to increase with the charge of the detected fragment up to Z = 3-4 and then turns into saturation for heavier fragments. Guided by simple simulations of an anisotropic expanding thermal source, we show that the value at saturation can provide a good estimate of the flow angle, $\Theta_{flow}$, in the participant region. It is found that $\Theta_{flow}$ depends strongly on the impact parameter. The excitation function of $\Theta_{flow}$ reveals striking deviations from the ideal hydrodynamical scaling. The data exhibit a steep rise of \Theta_{\flow} to a maximum at around 250-400 AMeV, followed by a moderate decrease as the bombarding energy increases further.Comment: 28 pages Revtex, 6 figures (ps files), to appear in Nucl.Phys.