2,293 research outputs found
Stability in Hamiltonian systems : applications to the restricted three-body problem
The N-body problem is a classical famous problem which has attracted a lot of attention. It consists of describing the complete behavior of all solutions of the equations of motions for a given initial condition. Still related to this kind of problem Euler in 1772 describe the three-body problem in his eort to study the motion of the moon. Later on Jacobi in 1836 brought forward the main mathematical interest in an even more specic part of the three body problem, namely the one which is reduced to a conservative two degrees of freedom problem. This has somehow brought up an extensive study on mechanics. Despite of all this eort of great mathematicians, in general the N-body problem for N> 2 is still unsolved
A Dynamically Diluted Alignment Model Reveals the Impact of Cell Turnover on the Plasticity of Tissue Polarity Patterns
The polarisation of cells and tissues is fundamental for tissue morphogenesis
during biological development and regeneration. A deeper understanding of
biological polarity pattern formation can be gained from the consideration of
pattern reorganisation in response to an opposing instructive cue, which we
here consider by example of experimentally inducible body axis inversions in
planarian flatworms. Our dynamically diluted alignment model represents three
processes: entrainment of cell polarity by a global signal, local cell-cell
coupling aligning polarity among neighbours and cell turnover inserting
initially unpolarised cells. We show that a persistent global orienting signal
determines the final mean polarity orientation in this stochastic model.
Combining numerical and analytical approaches, we find that neighbour coupling
retards polarity pattern reorganisation, whereas cell turnover accelerates it.
We derive a formula for an effective neighbour coupling strength integrating
both effects and find that the time of polarity reorganisation depends linearly
on this effective parameter and no abrupt transitions are observed. This allows
to determine neighbour coupling strengths from experimental observations. Our
model is related to a dynamic -Potts model with annealed site-dilution and
makes testable predictions regarding the polarisation of dynamic systems, such
as the planarian epithelium.Comment: Preprint as prior to first submission to Journal of the Royal Society
Interface. 25 pages, 6 figures, plus supplement (18 pages, contains 1 table
and 7 figures). A supplementary movie is available from
https://dx.doi.org/10.6084/m9.figshare.c388781
Kinetic Characterization and X-ray Structure of a Mutant of Haloalkane Dehalogenase with Higher Catalytic Activity and Modified Substrate Range
Conversion of halogenated aliphatics by haloalkane dehalogenase proceeds via the formation of a covalent alkyl-enzyme intermediate which is subsequently hydrolyzed by water. In the wild type enzyme, the slowest step for both 1,2-dichloroethane and 1,2-dibromoethane conversion is a unimolecular enzyme isomerization preceding rapid halide dissociation. Phenylalanine 172 is located in a helix-loop-helix structure that covers the active site cavity of the enzyme, interacts with the Clβ of 1,2-dichloroethane during catalysis, and could be involved in stabilization of this helix-loop-helix region of the cap domain of the enzyme. To obtain more information about the role of this residue in dehalogenase function, we performed a mutational analysis of position 172 and studied the kinetics and X-ray structure of the Phe172Trp enzyme. The Phe172Trp mutant had a 10-fold higher kcat/Km for 1-chlorohexane and a 2-fold higher kcat for 1,2-dibromoethane than the wild-type enzyme. The X-ray structure of the Phe172Trp enzyme showed a local conformational change in the helix-loop-helix region that covers the active site. This could explain the elevated activity for 1-chlorohexane of the Phe172Trp enzyme, since it allows this large substrate to bind more easily in the active site cavity. Pre-steady-state kinetic analysis showed that the increase in kcat found for 1,2-dibromoethane conversion could be attributed to an increase in the rate of an enzyme isomerization step that preceeds halide release. The observed conformational difference between the helix-loop-helix structures of the wild-type enzyme and the faster mutant suggests that the isomerization required for halide release could be a conformational change that takes place in this region of the cap domain of the dehalogenase. It is proposed that Phe172 is involved in stabilization of the helix-loop-helix structure that covers the active site of the enzyme and creates a rigid hydrophobic cavity for small apolar halogenated alkanes.
Vortices on Hyperbolic Surfaces
It is shown that abelian Higgs vortices on a hyperbolic surface can be
constructed geometrically from holomorphic maps , where is also
a hyperbolic surface. The fields depend on and on the metrics of and
. The vortex centres are the ramification points, where the derivative of
vanishes. The magnitude of the Higgs field measures the extent to which
is locally an isometry.
Witten's construction of vortices on the hyperbolic plane is rederived, and
new examples of vortices on compact surfaces and on hyperbolic surfaces of
revolution are obtained. The interpretation of these solutions as
SO(3)-invariant, self-dual SU(2) Yang--Mills fields on is also given.Comment: Revised version: new section on four-dimensional interpretation of
hyperbolic vortices added
Measurement of miniband parameters of a doped superlattice by photoluminescence in high magnetic fields
We have studied a 50/50\AA superlattice of GaAs/AlGaAs
composition, modulation-doped with Si, to produce
cm electrons per superlattice period. The modulation-doping was tailored
to avoid the formation of Tamm states, and photoluminescence due to interband
transitions from extended superlattice states was detected. By studying the
effects of a quantizing magnetic field on the superlattice photoluminescence,
the miniband energy width, the reduced effective mass of the electron-hole
pair, and the band gap renormalization could be deduced.Comment: minor typing errors (minus sign in eq. (5)
Ultrafast pump-probe dynamics in ZnSe-based semiconductor quantum-wells
Pump-probe experiments are used as a controllable way to investigate the
properties of photoexcited semiconductors, in particular, the absorption
saturation. We present an experiment-theory comparison for ZnSe quantum wells,
investigating the energy renormalization and bleaching of the excitonic
resonances. Experiments were performed with spin-selective excitation and
above-bandgap pumping. The model, based on the semiconductor Bloch equations in
the screened Hartree-Fock approximation, takes various scattering processes
into account phenomenologically. Comparing numerical results with available
experimental data, we explain the experimental results and find that the
electron spin-flip occurs on a time scale of 30 ps.Comment: 10 pages, 9 figures. Key words: nonlinear and ultrafast optics,
modeling of femtosecond pump-probe experiments, electron spin-flip tim
Absorption spectrum of a weakly n-doped semiconductor quantum well
We calculate, as a function of temperature and conduction band electron
density, the optical absorption of a weakly n-doped, idealized semiconductor
quantum well. In particular, we focus on the absorption band due to the
formation of a charged exciton. We conceptualize the charged exciton as an
itinerant excitation intimately linked to the dynamical response of itinerant
conduction band electrons to the appearance of the photo-generated valence band
hole. Numerical results for the absorption in the vicinity of the exciton line
are presented and the spectral weights associated with, respectively, the
charged exciton band and the exciton line are analyzed in detail. We find, in
qualitative agreement with experimental data, that the spectral weight of the
charged exciton grows with increasing conduction band electron density and/or
decreasing temperature at the expense of the exciton.Comment: 5 pages, 4 figure
Spin Liquid State around a Doped Hole in Insulating Cuprates
The numerically exact diagonalization study on small clusters of the t-J
model with the second- and third- neighbor hopping terms shows that a novel
spin liquid state is realized around a doped hole with momentum k=(pi,0) and
energy \sim 2J compared with that with (pi/2,pi/2) in insulating cuprates,
where the spin and charge degrees of freedom are approximately decoupled. Our
finding implies that the excitations in the insulating cuprates are mapped onto
the the d-wave resonating valence bond state.Comment: 4 pages, 4 EPS figures, to be published in J. Phys. Soc. Jpn. Vol.
69, No.1 January, 200
Free induction signal from biexcitons and bound excitons
A theory of the free induction signal from biexcitons and bound excitons is
presented. The simultaneous existence of the exciton continuum and a bound
state is shown to result in a new type of time dependence of the free
induction. The optically detected signal increases in time and oscillates with
increasing amplitude until damped by radiative or dephasing processes.
Radiative decay is anomalously fast and can result in strong picosecond pulses.
The expanding area of a coherent exciton polarization (inflating antenna),
produced by the exciting pulse, is the underlying physical mechanism. The
developed formalism can be applied to different biexciton transients.Comment: RevTeX, 20 p. + 2 ps fig. To appear in Phys. Rev. B1
- …
