1,001 research outputs found
High Voltage in Noble Liquids for High Energy Physics
A workshop was held at Fermilab November 8-9, 2013 to discuss the challenges
of using high voltage in noble liquids. The participants spanned the fields of
neutrino, dark matter, and electric dipole moment physics. All presentations at
the workshop were made in plenary sessions. This document summarizes the
experiences and lessons learned from experiments in these fields at developing
high voltage systems in noble liquids.Comment: 64 pages, 41 figures, 2 table
Hydrogen penetration into titanium from environment in different states
In this paper, the accumulation of hydrogen in titanium from media of different aggregate states is considered, since the accumulation of hydrogen in structural and functional materials, which ultimately can lead to the destruction of structures, essentially depends on the environments in which these structures operate. Obtained: electrolytic and plasma saturation is characterized by hydrogen entrapment by low-temperature traps with weak binding energy (point defects and their complexes, vacancies and their complexes, etc. The method of Siwerst is characterized by capture of high-temperature traps (microcracks of microcracks, intergranular boundaries, etc.)
Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium
Importance:
There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC).
Objective:
To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Design, Setting, and Participants:
This multicenter, prospective, case-control study was conducted by the National Collegiate Athletic Association (NCAA) and the US Department of Defense Concussion Assessment, Research, and Education (CARE) Consortium from February 20, 2015, to May 31, 2018, at 6 CARE Advanced Research Core sites. A total of 504 collegiate athletes with concussion, contact sport control athletes, and non-contact sport control athletes completed clinical testing and blood collection at preseason baseline, the acute postinjury period, 24 to 48 hours after injury, the point of reporting being asymptomatic, and 7 days after return to play. Data analysis was conducted from March 1 to November 30, 2019.
Main Outcomes and Measures:
Glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase-L1 (UCH-L1), neurofilament light chain, and tau were quantified using the Quanterix Simoa multiplex assay. Clinical outcome measures included the Sport Concussion Assessment Tool-Third Edition (SCAT-3) symptom evaluation, Standardized Assessment of Concussion, Balance Error Scoring System, and Brief Symptom Inventory 18.
Results:
A total of 264 athletes with concussion (mean [SD] age, 19.08 [1.24] years; 211 [79.9%] male), 138 contact sport controls (mean [SD] age, 19.03 [1.27] years; 107 [77.5%] male), and 102 non-contact sport controls (mean [SD] age, 19.39 [1.25] years; 82 [80.4%] male) were included in the study. Athletes with concussion had significant elevation in GFAP (mean difference, 0.430 pg/mL; 95% CI, 0.339-0.521 pg/mL; P < .001), UCH-L1 (mean difference, 0.449 pg/mL; 95% CI, 0.167-0.732 pg/mL; P < .001), and tau levels (mean difference, 0.221 pg/mL; 95% CI, 0.046-0.396 pg/mL; P = .004) at the acute postinjury time point compared with preseason baseline. Longitudinally, a significant interaction (group × visit) was found for GFAP (F7,1507.36 = 16.18, P < .001), UCH-L1 (F7,1153.09 = 5.71, P < .001), and tau (F7,1480.55 = 6.81, P < .001); the interaction for neurofilament light chain was not significant (F7,1506.90 = 1.33, P = .23). The area under the curve for the combination of GFAP and UCH-L1 in differentiating athletes with concussion from contact sport controls at the acute postinjury period was 0.71 (95% CI, 0.64-0.78; P < .001); the acute postinjury area under the curve for all 4 biomarkers combined was 0.72 (95% CI, 0.65-0.79; P < .001). Beyond SCAT-3 symptom score, GFAP at the acute postinjury time point was associated with the classification of athletes with concussion from contact controls (β = 12.298; 95% CI, 2.776-54.481; P = .001) and non-contact sport controls (β = 5.438; 95% CI, 1.676-17.645; P = .005). Athletes with concussion with loss of consciousness or posttraumatic amnesia had significantly higher levels of GFAP than athletes with concussion with neither loss of consciousness nor posttraumatic amnesia at the acute postinjury time point (mean difference, 0.583 pg/mL; 95% CI, 0.369-0.797 pg/mL; P < .001).
Conclusions and Relevance:
The results suggest that blood biomarkers can be used as research tools to inform the underlying pathophysiological mechanism of concussion and provide additional support for future studies to optimize and validate biomarkers for potential clinical use in SRC
Multiple hadron production in e+e- annihilation induced by heavy primary quarks. New analysis
In this paper we present an analysis of the multiple hadron production
induced by primary heavy quarks in e+e- annihilation with the account of most
complete and corrected experimental data. In the framework of perturbative QCD,
new theoretical bounds on the asymptotically constant differences of the
multiplicities in processes with light and heavy quarks are given.Comment: 26 pages, 7 figures, to be published in Particles & Nucle
Observation of single collisionally cooled trapped ions in a buffer gas
Individual Ba ions are trapped in a gas-filled linear ion trap and observed
with a high signal-to-noise ratio by resonance fluorescence. Single-ion storage
times of ~5 min (~1 min) are achieved using He (Ar) as a buffer gas at
pressures in the range 8e-5 - 4e-3 torr. Trap dynamics in buffer gases are
experimentally studied in the simple case of single ions. In particular, the
cooling effects of light gases such as He and Ar and the destabilizing
properties of heavier gases such as Xe are studied. A simple model is offered
to explain the observed phenomenology.Comment: 5 pages, 4 figures, accepted for publication in Phys. Rev. A. Minor
text and figure change
A magnetically-driven piston pump for ultra-clean applications
A magnetically driven piston pump for xenon gas recirculation is presented.
The pump is designed to satisfy extreme purity and containment requirements, as
is appropriate for the recirculation of isotopically enriched xenon through the
purification system and large liquid xenon TPC of EXO-200. The pump, using
sprung polymer gaskets, is capable of pumping more than 16 standard liters per
minute (SLPM) of xenon gas with 750 torr differential pressure.Comment: 6 pages, 5 figure
Investigation of radioactivity-induced backgrounds in EXO-200
The search for neutrinoless double-beta decay (0{\nu}{\beta}{\beta}) requires
extremely low background and a good understanding of their sources and their
influence on the rate in the region of parameter space relevant to the
0{\nu}{\beta}{\beta} signal. We report on studies of various {\beta}- and
{\gamma}-backgrounds in the liquid- xenon-based EXO-200 0{\nu}{\beta}{\beta}
experiment. With this work we try to better understand the location and
strength of specific background sources and compare the conclusions to
radioassay results taken before and during detector construction. Finally, we
discuss the implications of these studies for EXO-200 as well as for the
next-generation, tonne-scale nEXO detector.Comment: 9 pages, 7 figures, 3 table
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