User guide : Aquifer Productivity (Scotland) GIS Datasets. Version 2

This report describes a revised version (Version 2) of the aquifer productivity (Scotland) datasets produced by the British Geological Survey (BGS). There are two maps: bedrock aquifer productivity and superficial deposits aquifer productivity. Version 1 of these datasets was produced in 2004. Version 2 uses updated geological linework and a slightly modified methodology. The aquifer productivity maps describe the potential of aquifers across Scotland to sustain various levels of borehole water supply, and the dominant groundwater flow types in each aquifer. The bedrock aquifer productivity map has five aquifer productivity classes (very high, high, moderate, low and very low); and three groundwater flow categories (significant intergranular flow; mixed fracture/intergranular flow; and fracture flow). The superficial deposits productivity map has four productivity classes (high; moderate to high; moderate; and a category to signify that a deposit is ‘not a significant aquifer’). All superficial deposits aquifers in Scotland are assumed to have primarily intergranular groundwater flow. The aquifer productivity maps are a tool to indicate the location and productivity of aquifers across Scotland. They have been used to help characterise groundwater bodies as required by the Water Framework Directive, and may have several other uses, including in policy analysis and development; to prioritise aquifer and site investigations; to inform planning decisions; and to improve awareness of groundwater in general. The complexity and heterogeneity of geological formations means that the maps are only a guide. They are designed to be used at a scale of 1:100,000, and not to assess aquifer conditions at a single point

Knowledge transfer and exchange: a look at the literature in relation to research and policy

Within the field of health policy, there have been widespread calls for the increased or improved use of evidence within policy making. This reflects an ambition to deliver better policy in terms of outcomes, resource efficiency and effectiveness, and a belief that this can be achieved through utilising the available evidence to inform and guide decision making. For those tasked with improving the uptake of a piece or body of evidence, for policy makers aiming to improve their evidence use, or for researches investigating this question, a number of conceptual questions remain on how to actually achieve this, such as: What should count as evidence for policy making? Who should govern (or steer) the use of research evidence for policy? What is ‘good evidence’ for decision making? What is the ‘good use’ of evidence from a governance perspective? How is research knowledge typically translated into policy? How can one ‘improve’ the use or uptake of evidence in policy making? The GRIP-Health Project is a 5 year, European Research Council supported programme of work that aims to improve the use of research evidence in health policy through undertaking research on the political aspects of health policy making and evidence use. The project has developed a number of working papers that engage with some of these topics.1 This current paper is concerned with the last two of the questions listed above, specifically reviewing key aspects of Knowledge Transfer and Exchange (KTE) related to getting research into policy and practice. While the health sector is increasingly motivated by a desire to get research evidence into policy, outside the field of health there is a much broader body of work that is specifically concerned with how evidence and knowledge are transferred, translated, or taken up by different policy actors. Various theories attempt to establish how KTE works, the contextual factors that influence the process, and how to achieve maximum impact for relevant bodies of evidence. Acronyms and terminology used in this field vary accordingly, and can include knowledge transfer, knowledge translation, knowledge management, and knowledge brokering. These various terms have been grouped together under the rubric ‘K*’ by some authors to reflect the multiple overlapping terms 2 Prior working papers in this series deal with aspects of: Stewardship of health evidence; hierarches and appropriateness of evidence; and institutional approaches to evidence uptake research. Working papers and other outputs of the programme are available at the GRIP-Health website http://www.lshtm.ac.uk/groups/griphealth/resources/index.html 3 (c.f. Shaxson et al., 2012). However, in this paper, we use the term KTE to refer to the general body of literature focused on issues of knowledge production, dissemination, uptake and use in policymaking. As the body of work on KTE is extensive, it was decided not to attempt a complete or systematic review of the literature. There are, however, several papers which attempt to synthesise the existing literature or systematically review elements of the KTE field. These reviews provide a starting point for mapping the field to help inform efforts to improve the use of research evidence in policy. The current paper therefore has two objectives. First, it summarises and synthesises a set of identified KTE review papers in order to undertake a comparison of their similarities and their differences on the main areas they cover, to provide a basic mapping of key KTE concepts. After this, it then explores some key themes that emerge from the KTE literature which are of particular relevance to the GRIP-Health programme and other researchers or stakeholders who are tasked with improving evidence uptake

Olanzapine Attenuates Cue-elicited Craving for Tobacco

Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures in cue-elicited craving for tobacco. Objective: If mesolimbic dopamine activity is associated with cue-elicited craving for tobacco, a dopamine antagonist should attenuate cueelicited craving for tobacco. Thus, the aim of the present study was to determine whether an atypical antipsychotic (olanzapine, 5 mg) decreased cue-elicited craving for tobacco. Method: Participants were randomly assigned to 5 days of pretreatment with olanzapine (5 mg; n=31) or were randomly assigned to 5 days of a matching placebo (n=28). Approximately 8 h after the last dose, participants were exposed to a control cue (pencil) followed by exposure to smoking cues. Participants subsequently smoked either nicotine cigarettes or de-nicotinized cigarettes. Results: Olanzapine attenuated cue-elicited craving for tobacco but did not moderate the subjective effects of smoking. Discussion: This study represents one of the first investigations of the effect of atypical antipsychotics on cue-elicited craving for tobacco. The results suggest that medications with similar profiles may reduce cue-elicited craving, which in turn, may partially explain recent observations that atypical antipsychotics may reduce substance use

A systems approach to the development and use of FMEA in complex automotive applications

YesThe effective deployment of FMEAs within complex automotive applications faces a number of challenges, including the complexity of the system being analysed, the need to develop a series of coherently linked FMEAs at different levels within the systems hierarchy and across intrinsically interlinked engineering disciplines, and the need for coherent linkage between critical design characteristics cascaded through the systems levels with their counterparts in manufacturing. The approach presented in this paper to address these challenges is based on a structured Failure Mode Avoidance (FMA) framework which promotes the development of FMEAs within an integrated Systems Engineering approach. The effectiveness of the framework is illustrated through a case study, centred on the development of a diesel exhaust aftertreatment system. This case study demonstrates that the structured FMA framework for function analysis supports an effective decomposition of complex interdisciplinary systems facilitating the DFMEA deployment through a series of containable, structured DFMEAs developed at successive system levels, with clear vertical integration of functional requirements and critical parameters cascade. The paper also discusses the way in which the approach supports deployment across engineering disciplines and domains, ensuring the integrity of information flow between the design and manufacturing activities

Stability of hexagonal solidification patterns

We investigate the dynamics of cellular solidification patterns using three-dimensional phase-field simulations. The cells can organize into stable hexagonal patterns or exhibit unsteady evolutions. We identify the relevant secondary instabilities of regular hexagonal arrays and find that the stability boundaries depend significantly on the strength of crystalline anisotropy. We also find multiplet states that can be reached by applying well-defined perturbations to a pre-existing hexagonal array.Comment: Minor changes, mainly in introduction and conclusion, one reference adde

Meteoroid hazards in deep space Final report

Design and development of Sisyphus meteoroid detection system for interplanetary spacecraf

Assessment of the benefits of user involvement in health research from the Warwick Diabetes Care Research User Group : a qualitative case study

Objective  To assess the benefits of involving health-care users in diabetes research. Design and participants  For this qualitative case study, semi-structured interviews were conducted with researchers who had worked extensively with the group. During regular meetings of the Research User Group, members discussed their views of the group's effectiveness as part of the meeting's agenda. Interviews and discussions were transcribed, coded using N-Vivo software and analysed using constant comparative methods. Results  Involvement of users in research was generally seen as contributing to effective and meaningful research. However, the group should not be considered to be representative of the patient population or participants of future trials. An important contributor to the group's success was its longstanding nature, enabling users to gain more insight into research and form constructive working relationships with researchers. The user-led nature of the group asserted itself, especially, in the language used during group meetings. A partial shift of power from researchers to users was generally acknowledged. Users' main contribution was their practical expertise in living with diabetes, but their involvement also helped researchers to remain connected to the `real world' in which research would be applied. While the group's work fulfilled established principles of consumer involvement in research, important contributions relying on personal interaction between users and researchers were hard to evaluate by process measures alone. Conclusions  We demonstrated the feasibility, acceptability and effectiveness of this longstanding, experienced, lay-led research advisory group. Its impact on research stems from the continuing interaction between researchers and users, and the general ethos of learning from each other in an on-going process. Both process measures and qualitative interviews with stakeholders are needed to evaluate the contributions of service users to health research

Complex search task: how to make a phone safe for a child

There are many factors in task design that might make it ‘complex’: having multiple components, having multiple cross-dependent components, tasks that involve comparison, evaluation, estimation, or learning. In this paper, we discuss a case study of a complex task we may consider to be highly natural, a common concern for many people, and one that ‘should’ have a clear answer, but doesn’t: how do you make a phone safe for a child. For this question, there is a lot of opinion online, many possibilities for actions, many variations in hardware and software, but ultimately no one clear and correct answer for everyday phone users. We found very little objective behaviours that separated people in terms of performance but instead have begun to identify some successful tactics that are not directly linked to domain knowledge

The Effects of Negative Legacies on the Adjustment of Parentally Bereaved Children and Adolescents

This is a report of a qualitative analysis of a sample of bereaved families in which one parent died and in which children scored in the clinical range on the Child Behavior Check List. The purpose of this analysis was to learn more about the lives of these children. They were considered to be at risk of developing emotional and behavioral problems associated with the death. We discovered that many of these “high risk” children had a continuing bond with the deceased that was primarily negative and troubling for them in contrast to a comparison group of children not at risk from the same study. Five types of legacies, not mutually exclusive, were identified: health related, role related, personal qualities, legacy of blame, and an emotional legacy. Coping behavior on the part of the surviving parent seemed to make a difference in whether or not a legacy was experienced as negative