An Integrative Review of Web 3.0 in Academic Libraries

Purpose – The aim of this paper is to present an integrated literature review exploring the nature of responsive, semantic and interactive Web 3.0 technologies applicable for academic libraries. Design/methodology/approach – We conducted an integrated review of the literature combining a strategy of automated and keywords search. The main source for identifying the studies are Emerald Library Studies and Information & Knowledge Management eJournals, Web of Knowledge, and Library, Information Science & Technology Abstracts (EBSCO) databases. To this end, a sample of (n= 140) studies were analyzed to characterize the Web 3.0 trends and its applications based on theme, years and document types. Findings – A review of literature reveals that Web 3. needs evaluation as to what extent they are integrated, deployed and mainstreamed into library services and in information management practices. It is important to develop a conceptual framework that explores the linkages of Web 3.0 technologies and their applications in academic libraries. Originality/value –This review shows how Web 3.0 technologies enhance library services in its holistic conceptualization and how academic libraries are moving into a more robust, inclusive and adaptable phase in their service values and innovation

Importance of Dietary Carotenoid Pigment (Astaxanthin) in aquaculture

India is bestowed with rich aquatic resources, both marine and freshwater. These provide an increasing scope for stepping up fish production. So much so, Indian seafood industry achieved a remarkable place in the world seafood trade (Rs.6300 crores, MPEDA, 2001)

Successful orthotopic liver transplantation in an adult patient with sickle cell disease and review of the literature

Sickle cell disease can lead to hepatic complications ranging from acute hepatic crises to chronic liver disease including intrahepatic cholestasis, and iron overload. Although uncommon, intrahepatic cholestasis may be severe and medical treatment of this complication is often ineffective. We report a case of a 37 year-old male patient with sickle cell anemia, who developed liver failure and underwent successful orthotopic liver transplantation. Both pre and post-operatively, he was maintained on red cell transfusions. He remains stable with improved liver function 42 months post transplant. The role for orthotopic liver transplantation is not well defined in patients with sickle cell disease, and the experience remains limited. Although considerable challenges of post-transplant graft complications remain, orthotopic liver transplantation should be considered as a treatment option for sickle cell disease patients with end-stage liver disease who have progressed despite conventional medical therapy. An extended period of red cell transfusion support may lessen the post-operative complications

Unified Angular Momentum of Dyons

Unified quaternionic angular momentum for the fields of dyons and gravito-dyons has been developed and the commutation relations for dynamical variables are obtained in compact and consistent manner. Demonstrating the quaternion forms of unified fields of dyons (electromagnetic fields) and gravito-dyons (gravito-Heavisidian fields of linear gravity), corresponding quantum equations are reformulated in compact, simpler and manifestly covariant way

A review of segmentation and deformable registration methods applied to adaptive cervical cancer radiation therapy treatment planning

Objective: Manual contouring and registration for radiotherapy treatment planning and online adaptation for cervical cancer radiation therapy in computed tomography (CT) and magnetic resonance images (MRI) are often necessary. However manual intervention is time consuming and may suffer from inter or intra-rater variability. In recent years a number of computer-guided automatic or semi-automatic segmentation and registration methods have been proposed. Segmentation and registration in CT and MRI for this purpose is a challenging task due to soft tissue deformation, inter-patient shape and appearance variation and anatomical changes over the course of treatment. The objective of this work is to provide a state-of-the-art review of computer-aided methods developed for adaptive treatment planning and radiation therapy planning for cervical cancer radiation therapy. Methods: Segmentation and registration methods published with the goal of cervical cancer treatment planning and adaptation have been identified from the literature (PubMed and Google Scholar). A comprehensive description of each method is provided. Similarities and differences of these methods are highlighted and the strengths and weaknesses of these methods are discussed. A discussion about choice of an appropriate method for a given modality is provided. Results: In the reviewed papers a Dice similarity coefficient of around 0.85 along with mean absolute surface distance of 2-4. mm for the clinically treated volume were reported for transfer of contours from planning day to the treatment day. Conclusions: Most segmentation and non-rigid registration methods have been primarily designed for adaptive re-planning for the transfer of contours from planning day to the treatment day. The use of shape priors significantly improved segmentation and registration accuracy compared to other models

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis.

Progressive liver fibrosis is characterized by the deposition of collagen by activated hepatic stellate cells (HSCs). Activation of HSCs is a multiple receptor-driven process in which profibrotic signals are enhanced and antifibrotic pathways are suppressed. Here we report the discovery of a signalling platform comprising G protein subunit, Gαi and GIV, its guanine exchange factor (GEF), which serves as a central hub within the fibrogenic signalling network initiated by diverse classes of receptors. GIV is expressed in the liver after fibrogenic injury and is required for HSC activation. Once expressed, GIV enhances the profibrotic (PI3K-Akt-FoxO1 and TGFβ-SMAD) and inhibits the antifibrotic (cAMP-PKA-pCREB) pathways to skew the signalling network in favour of fibrosis, all via activation of Gαi. We also provide evidence that GIV may serve as a biomarker for progression of fibrosis after liver injury and a therapeutic target for arresting and/or reversing HSC activation during liver fibrosis

Sleep During Pregnancy: The nuMoM2b Pregnancy and Sleep Duration and Continuity Study

Study Objectives: To characterize sleep duration, timing and continuity measures in pregnancy and their association with key demographic variables. Methods: Multisite prospective cohort study. Women enrolled in the nuMoM2b study (nulliparous women with a singleton gestation) were recruited at the second study visit (16-21 weeks of gestation) to participate in the Sleep Duration and Continuity substudy. Women <18 years of age or with pregestational diabetes or chronic hypertension were excluded from participation. Women wore a wrist activity monitor and completed a sleep log for 7 consecutive days. Time in bed, sleep duration, fragmentation index, sleep efficiency, wake after sleep onset, and sleep midpoint were averaged across valid primary sleep periods for each participant. Results: Valid data were available from 782 women with mean age of 27.3 (5.5) years. Median sleep duration was 7.4 hours. Approximately 27.9% of women had a sleep duration of 9 hours. In multivariable models including age, race/ethnicity, body mass index, insurance status, and recent smoking history, sleep duration was significantly associated with race/ethnicity and insurance status, while time in bed was only associated with insurance status. Sleep continuity measures and sleep midpoint were significantly associated with all covariates in the model, with the exception of age for fragmentation index and smoking for wake after sleep onset. Conclusions: Our results demonstrate the relationship between sleep and important demographic characteristics during pregnancy

Quaternion Gravi-Electromagnetism

Defining the generalized charge, potential, current and generalized fields as complex quantities where real and imaginary parts represent gravitation and electromagnetism respectively, corresponding field equation, equation of motion and other quantum equations are derived in manifestly covariant manner. It has been shown that the field equations are invariant under Lorentz as well as duality transformations. It has been shown that the quaternionic formulation presented here remains invariant under quaternion transformations.Comment: Key Words: Quaternion, dyons, gravito-dyons, gravi-electromagnetism. PACS No.: 04.90. +e ; 14.80. H

A community-based study on reproductive empowerment of women aged 15-49 years and associated factors in a rural area of Delhi

Background: Reproductive health disparities persist globally, with a significant proportion of women lacking access to modern contraception despite desiring to control their fertility, leading to a substantial number of unintended pregnancies. This study aimed to assess the level of reproductive empowerment among married women in rural areas, specifically focusing on communication, decision-making, social support, and norms related to reproductive health. Methods: A cross-sectional study was conducted in the rural areas of south Delhi, with a sample size of 215 married women aged 15-49 years. Systematic random sampling was employed, and data was collected using a semi-structured questionnaire validated in Hindi. The reproductive empowerment (RE) scale was utilized, comprising sub-scales related to healthcare provider communication, partner communication, decision-making, social support, and social norms. Data analysis was performed using SPSS software, with a significance level set at p&lt;0.05. Results: The study reveals that 54.8% of the participants exhibited high levels of reproductive empowerment. The mean RE score was 3.09±0.39 out of 4, indicating moderate to high levels of empowerment. Sub-scale analysis showed higher scores in healthcare provider communication (3.91±0.28) compared to decision-making (2.93±0.65), partner communication (3.53±0.69), social support (2.19±0.89), and social norms (2.13±0.69). Conclusions: This study underscores the importance of exploring reproductive empowerment as a specific entity and advocates for further research and interventions to promote women’s agency and decision-making autonomy in matters of reproductive health

A prospective study on the role of Hysterolaparoscopy in the evaluation of infertility

Background: Infertility affects about 10-15% of couples of reproductive age groups. The current evidence indicates a 9% prevalence of infertility with 56% of couples seeking medical care. Hysterolaparoscopy provides a comprehensive investigative procedure in which various factors causing female infertility can be assessed at one sitting.Methods: A total 100 infertile women between 20-40 years of age including primary and secondary infertility were evaluated. Patients would be investigated thoroughly for infertility and in preparation for anaesthesia. Tests include follicular study, Ultrasound pelvis. Hysterolaparoscopy was performed in the pre ovulatory period between days 6-10 of the cycle for infertility evaluation.Results: In the present study out of 100 cases for infertility evaluated, primary infertility were 57(57%) and secondary infertility were 43(43%). In our study out of 100 patients, Hysterolaparoscopy showed tuberculosis in 24 (24%) patients, remaining were endometriosis, polycystic ovarian syndrome, congestion, intra-pelvic adhesions, hydro-salpinx.Conclusions: It is concluded that while treating the causes of female infertility combined simultaneous diagnostic laparoscopy and hysteroscopy should be performed in all infertile patients as” seeing is believing” and if any pathologies found to be operable the gynaecologist can perform operative hystero-laparoscopy at that time, hence anticipating the pathologies after pre-operative work up is very important